You are currently viewing a new version of our website. To view the old version click .

Toxics, Volume 12, Issue 9

September 2024 - 68 articles

Cover Story: Per- and polyfluoroalkyl substances (PFAS) are a large chemical class with wide-ranging industrial applications for which only limited toxicity data are available for human health evaluation. To address the lack of TK data, a pooled primary human hepatocyte suspension model was used with targeted liquid chromatography–mass spectrometry to investigate substrate depletion for 54 PFAS. Of the 54 PFAS compounds in this study, 35 displayed no substrate depletion, while a median value of 4.5 μL/(min x million cells) was observed across PFAS compounds that showed appreciable clearance. This effort greatly expands the PFAS in vitro TK dataset, enabling refined TK modeling, in silico tool development, and NAM-based human health evaluations across this important set of emerging contaminants. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (68)

  • Article
  • Open Access
5 Citations
1,928 Views
15 Pages

Efficacy of Thymoquinone and Hesperidin in Attenuating Cardiotoxicity from 5-Fluorouracil: Insights from In Vivo and In Silico Studies

  • Juveriya Farooq,
  • Rokeya Sultana,
  • Jainey P. James,
  • Zakiya Fathima C,
  • Ali F. Almutairy and
  • Abubakar Siddique Mustafa Hussain

23 September 2024

5-Fluorouracil (5-FU) is widely used in chemotherapy but poses serious risks of cardiotoxicity, which can significantly affect treatment outcomes. Identifying interventions that can prevent these adverse effects without undermining anticancer efficac...

  • Article
  • Open Access
1 Citations
1,541 Views
15 Pages

Characteristics and Mechanism of Hematite Dissolution and Release on Arsenic Migration in Heterogeneous Materials

  • Zheying Li,
  • Huimei Shan,
  • Wanyue Rong,
  • Zhicheng Zhao,
  • Kexin Ma,
  • Sanxi Peng and
  • Song Wei

23 September 2024

The migration of arsenic in groundwater is influenced by the heterogeneity of the medium, and the presence of iron minerals adds complexity and uncertainty to this effect. In this study, a stratified heterogeneous sand column with an embedded hematit...

  • Review
  • Open Access
3 Citations
1,809 Views
12 Pages

Distribution Characteristics and Ecological Risk Assessment of Organophosphate Esters in Surface Soils of China

  • Guorui Zhou,
  • Yizhang Zhang,
  • Ziye Wang,
  • Mingrui Li,
  • Haiming Li and
  • Chen Shen

23 September 2024

The chemical flame retardants represented by organophosphate esters (OPEs) are widely used and have a serious impact on the environment. In this study, we collected data on the exposure levels of ten OPEs in Chinese soils in recent years and performe...

  • Article
  • Open Access
5 Citations
1,859 Views
15 Pages

22 September 2024

Tangshan, a major industrial and agricultural center in northern China, frequently experiences significant PM2.5 pollution events during winter, impacting its large population. These pollution episodes are influenced by multi–scale meteorologic...

  • Article
  • Open Access
5 Citations
2,229 Views
16 Pages

21 September 2024

The harmful algal bloom (HAB) liver toxin microcystin (MC) and trace element biomagnification were previously detected in organisms in the Indian River Lagoon (IRL), Florida. Since there are no routine screening programs for these contaminants, liver...

  • Article
  • Open Access
3 Citations
1,503 Views
22 Pages

20 September 2024

This study assessed the presence of potentially toxic elements (PTEs) in China’s northeastern black soil belt, an area with limited prior research. We collected 304 soil samples (0–20 cm) from Gonghe Town, Hailun City, and analyzed the PT...

  • Article
  • Open Access
3 Citations
1,636 Views
18 Pages

Health Risk Assessment of Residents’ Exposure to Air Pollutants around the Sinpyeong–Jangrim Industrial Complex in Busan

  • Ji-Yun Jung,
  • Jong-Won Kim,
  • Tae-Woo Koo,
  • Joon-Young Heo,
  • Ye-Seul Jeong and
  • Cheol-Min Lee

20 September 2024

In this study, we aimed to evaluate the health effects of heavy metals and volatile organic compounds (VOCs) in fine particulate matter (PM2.5) in the air around the Sinpyeong–Jangrim Industrial Complex, Busan, and the necessity of reduction me...

  • Article
  • Open Access
4 Citations
1,840 Views
21 Pages

20 September 2024

Catalytic ozone oxidation, which is characterized by strong oxidizing properties and environmental friendliness, has been widely used in organic wastewater treatments. However, problems such as a low organic pollutant removal efficiency and unstable...

  • Communication
  • Open Access
3 Citations
2,369 Views
11 Pages

Monitoring of Non-Maximum-Residue-Level Pesticides in Animal Feed: A Study from 2019 to 2023

  • Roberta Giugliano,
  • Vittoria Armenio,
  • Valentina Savio,
  • Erica Vaccaro,
  • Valentina Ciccotelli and
  • Barbara Vivaldi

19 September 2024

Pesticides play a critical role in modern agriculture by protecting crops and ensuring higher yields, but their widespread use raises concerns about human health and environmental impact. Regulatory agencies impose Maximum Residue Levels (MRLs) to en...

  • Article
  • Open Access
3 Citations
2,935 Views
14 Pages

Fluoride Exposure from Drinking Water Increases the Risk of Stroke: An Ecological Study in Changwu Town, China

  • Lin Yuan,
  • Hongna Sun,
  • Yue Li,
  • Zhifeng Xing,
  • Shihui Yin,
  • Fengyu Xie,
  • Jing Zhou,
  • Shuang Li,
  • Liaowei Wu and
  • Wei Huang
  • + 4 authors

18 September 2024

Background: Stroke is a major cause of death globally and the leading cause in China. Excessive fluoride exposure has been linked to cardiovascular conditions related to stroke risk factors such as hypertension, atherosclerosis, dyslipidemia, and car...

of 7

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Toxics - ISSN 2305-6304