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Proteomes, Volume 10, Issue 2

June 2022 - 13 articles

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Articles (13)

  • Article
  • Open Access
10 Citations
7,067 Views
16 Pages

Survey of Anti-Pathogen Antibody Levels in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

  • Adam J. O’Neal,
  • Katherine A. Glass,
  • Christopher J. Emig,
  • Adela A. Vitug,
  • Steven J. Henry,
  • Dikoma C. Shungu,
  • Xiangling Mao,
  • Susan M. Levine and
  • Maureen R. Hanson

Infectious pathogens are implicated in the etiology of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) because of the occurrence of outbreaks of the disease. While a number of different infectious agents have been associated with the onse...

  • Article
  • Open Access
3 Citations
3,846 Views
21 Pages

Dysregulated Gene Expression in Lymphoblasts from Parkinson’s Disease

  • Sarah Jane Annesley,
  • Claire Yvonne Allan,
  • Oana Sanislav,
  • Andrew Evans and
  • Paul Robert Fisher

Parkinson’s disease is the second largest neurodegenerative disease worldwide and is caused by a combination of genetics and environment. It is characterized by the death of neurons in the substantia nigra of the brain but is not solely a disea...

  • Article
  • Open Access
31 Citations
8,051 Views
23 Pages

A Comparison of Blood Plasma Small Extracellular Vesicle Enrichment Strategies for Proteomic Analysis

  • Natalie P. Turner,
  • Pevindu Abeysinghe,
  • Keith A. Kwan Cheung,
  • Kanchan Vaswani,
  • Jayden Logan,
  • Pawel Sadowski and
  • Murray D. Mitchell

Proteomic analysis of small extracellular vesicles (sEVs) poses a significant challenge. A ‘gold-standard’ method for plasma sEV enrichment for downstream proteomic analysis is yet to be established. Methods were evaluated for their capac...

  • Article
  • Open Access
11 Citations
4,790 Views
17 Pages

Pattern Analysis of Organellar Maps for Interpretation of Proteomic Data

  • Jordan B. Burton,
  • Nicholas J. Carruthers,
  • Zhanjun Hou,
  • Larry H. Matherly and
  • Paul M. Stemmer

Localization of organelle proteins by isotope tagging (LOPIT) maps are a coordinate-directed representation of proteome data that can aid in biological interpretation. Analysis of organellar association for proteins as displayed using LOPIT is evalua...

  • Review
  • Open Access
37 Citations
7,944 Views
36 Pages

Wheat Proteomics for Abiotic Stress Tolerance and Root System Architecture: Current Status and Future Prospects

  • Tanushree Halder,
  • Mukesh Choudhary,
  • Hui Liu,
  • Yinglong Chen,
  • Guijun Yan and
  • Kadambot H. M. Siddique

Wheat is an important staple cereal for global food security. However, climate change is hampering wheat production due to abiotic stresses, such as heat, salinity, and drought. Besides shoot architectural traits, improving root system architecture (...

  • Review
  • Open Access
106 Citations
8,985 Views
24 Pages

Applications of Proteomics in Ovarian Cancer: Dawn of a New Era

  • Aruni Ghose,
  • Sri Vidya Niharika Gullapalli,
  • Naila Chohan,
  • Anita Bolina,
  • Michele Moschetta,
  • Elie Rassy and
  • Stergios Boussios

The ability to identify ovarian cancer (OC) at its earliest stages remains a challenge. The patients present an advanced stage at diagnosis. This heterogeneous disease has distinguishable etiology and molecular biology. Next-generation sequencing cha...

  • Article
  • Open Access
7 Citations
4,941 Views
20 Pages

Proteomes of Uropathogenic Escherichia coli Growing in Human Urine and in J82 Urinary Bladder Cells

  • Sisse Andersen,
  • Arkadiusz Nawrocki,
  • Andreas Eske Johansen,
  • Ana Herrero-Fresno,
  • Vanesa García Menéndez,
  • Jakob Møller-Jensen and
  • John Elmerdahl Olsen

Uropathogenic Escherichia coli (UPEC) are the most common cause of urinary tract infection (UTI). UPEC normally reside in the intestine, and during establishment of UTI, they undergo metabolic adaptations, first to urine and then upon tissue invasion...

  • Article
  • Open Access
10 Citations
3,992 Views
26 Pages

Arteriovenous fistulas (AVFs), created for hemodialysis in end-stage renal disease patients, mature through the outward remodeling of the outflow vein. However, early thrombosis and chronic inflammation are detrimental to the process of AVF maturatio...

  • Review
  • Open Access
5 Citations
10,178 Views
21 Pages

Insights on Proteomics-Driven Body Fluid-Based Biomarkers of Cervical Cancer

  • Amrita Mukherjee,
  • Chinmayi Bhagwan Pednekar,
  • Siddhant Sujit Kolke,
  • Megha Kattimani,
  • Subhiksha Duraisamy,
  • Ananya Raghu Burli,
  • Sudeep Gupta and
  • Sanjeeva Srivastava

Cervical cancer is one of the top malignancies in women around the globe, which still holds its place despite being preventable at early stages. Gynecological conditions, even maladies like cervical cancer, still experience scrutiny from society owin...

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Proteomes - ISSN 2227-7382