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Metabolites, Volume 7, Issue 1

March 2017 - 11 articles

Cover Story: Exercise plays a primary role in the treatment of the metabolic syndrome (MetS), a cluster of risk factors that raises morbidity. However, the optimal exercise parameters remain undetermined. Metabolomics can provide new insights into exercise metabolism. We investigated whether the response of the urinary metabolic fingerprint to exercise depends on the presence of MetS or exercise mode. Overall, men with MetS exhibited a blunted metabolic response to exercise compared to healthy men. The metabolic fingerprint responded diversely to three fundamentally different exercise modes, while the metabolic response to exercise gradually subsided to baseline on the following day. Further investigations may bring us closer to personalized exercise prescription for individuals with cardiometabolic risk factors. View the paper

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Communication

54 Citations

9,103 Views

13 Pages

Fully Automated Trimethylsilyl (TMS) Derivatisation Protocol for Metabolite Profiling by GC-MS

Erica Zarate,
Veronica Boyle,
Udo Rupprecht,
Saras Green,
Silas G. Villas-Boas,
Philip Baker and
Farhana R. Pinu

Metabolites2017, 7(1), 1;https://doi.org/10.3390/metabo7010001

29 December 2016

Gas Chromatography-Mass Spectrometry (GC-MS) has long been used for metabolite profiling of a wide range of biological samples. Many derivatisation protocols are already available and among these, trimethylsilyl (TMS) derivatisation is one of the mos...

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Metabolites - ISSN 2218-1989

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