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Metabolites, Volume 6, Issue 2

2016 June - 8 articles

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Articles (8)

  • Article
  • Open Access
23 Citations
10,617 Views
11 Pages

Complex Mixture Analysis of Organic Compounds in Yogurt by NMR Spectroscopy

  • Yi Lu,
  • Fangyu Hu,
  • Takuya Miyakawa and
  • Masaru Tanokura

NMR measurements do not require separation and chemical modification of samples and therefore rapidly and directly provide non-targeted information on chemical components in complex mixtures. In this study, one-dimensional (1H, 13C, and 31P) and two-...

  • Article
  • Open Access
44 Citations
16,055 Views
24 Pages

Detection of Volatile Metabolites of Garlic in Human Breast Milk

  • Laura Scheffler,
  • Yvonne Sauermann,
  • Gina Zeh,
  • Katharina Hauf,
  • Anja Heinlein,
  • Constanze Sharapa and
  • Andrea Buettner

The odor of human breast milk after ingestion of raw garlic at food-relevant concentrations by breastfeeding mothers was investigated for the first time chemo-analytically using gas chromatography−mass spectrometry/olfactometry (GC-MS/O), as well as...

  • Article
  • Open Access
6 Citations
6,448 Views
15 Pages

Development of Database Assisted Structure Identification (DASI) Methods for Nontargeted Metabolomics

  • Lochana C. Menikarachchi,
  • Ritvik Dubey,
  • Dennis W. Hill,
  • Daniel N. Brush and
  • David F. Grant

Metabolite structure identification remains a significant challenge in nontargeted metabolomics research. One commonly used strategy relies on searching biochemical databases using exact mass. However, this approach fails when the database does not c...

  • Feature Paper
  • Article
  • Open Access
9 Citations
7,984 Views
15 Pages

Metabolic Effect of Estrogen Receptor Agonists on Breast Cancer Cells in the Presence or Absence of Carbonic Anhydrase Inhibitors

  • Anissa Belkaid,
  • Miroslava Čuperlović-Culf,
  • Mohamed Touaibia,
  • Rodney J. Ouellette and
  • Marc E. Surette

Metabolic shift is one of the major hallmarks of cancer development. Estrogen receptor (ER) activity has a profound effect on breast cancer cell growth through a number of metabolic changes driven by its effect on transcription of several enzymes, in...

  • Review
  • Open Access
9 Citations
7,041 Views
9 Pages

Muscle weakness in corticosteroid myopathy is mainly the result of the destruction and atrophy of the myofibrillar compartment of fast-twitch muscle fibers. Decrease of titin and myosin, and the ratio of nebulin and MyHC in myopathic muscle, shows th...

  • Article
  • Open Access
11 Citations
6,151 Views
17 Pages

Sexual Dimorphism in the Response of Mercurialis annua to Stress

  • Ezra M. Orlofsky,
  • Giorgi Kozhoridze,
  • Lyudmila Lyubenova,
  • Elena Ostrozhenkova,
  • J. Barbro Winkler,
  • Peter Schröder,
  • Adelbert Bacher,
  • Wolfgang Eisenreich,
  • Micha Guy and
  • Avi Golan-Goldhirsh

The research presented stemmed from the observations that female plants of the annual dioecious Mercurialis annua outlive male plants. This led to the hypothesis that female plants of M. annua would be more tolerant to stress than male plants. This h...

  • Article
  • Open Access
3 Citations
7,044 Views
14 Pages

Pseudomonas putida strains can adapt and overcome the activity of toxic organic solvents by the employment of several resistant mechanisms including efflux pumps and modification to lipopolysaccharides (LPS) in their membranes. Divalent cations such...

  • Article
  • Open Access
7 Citations
5,245 Views
12 Pages

Accurate Measurement of the in vivo Ammonium Concentration in Saccharomyces cerevisiae

  • Hugo F. Cueto-Rojas,
  • Reza Maleki Seifar,
  • Angela Ten Pierick,
  • Sef J. Heijnen and
  • Aljoscha Wahl

Ammonium (NH4+) is the most common N-source for yeast fermentations, and N-limitation is frequently applied to reduce growth and increase product yields. While there is significant molecular knowledge on NH4+ transport and assimilation, there have be...

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Metabolites - ISSN 2218-1989