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Metabolic Flux Distribution during Defatting of Steatotic Human Hepatoma (HepG2) Cells
- Gabriel Yarmush,
- Lucas Santos,
- Joshua Yarmush,
- Srivathsan Koundinyan,
- Mubasher Saleem,
- Nir I. Nativ,
- Rene S. Schloss,
- Martin L. Yarmush,
- Timothy J. Maguire and
- Francois Berthiaume
Methods that rapidly decrease fat in steatotic hepatocytes may be helpful to recover severely fatty livers for transplantation. Defatting kinetics are highly dependent upon the extracellular medium composition; however, the pathways involved are poor...

