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Diseases, Volume 8, Issue 3

September 2020 - 11 articles

Cover Story: The attack of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) severely affected global public health resulting in the outbreak of the novel coronavirus disease (COVID-19) pandemic. Despite an enormous amount of scientific research, administrative strategies, and economic measurements, differences still exist in facts, opinions, and implementation methods creating additional layers of complexities and conflicts. In this timely review, we have systematically summarized recent, important, and overall inclusive progress amid controversies about epidemiological studies, biological properties, clinical features, diagnostic methods, treatment modalities, and preventive measurements of COVID-19. This review would illuminate the grey areas for further improvement in the battle for survival. View this paper.
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Articles (11)

  • Review
  • Open Access
19 Citations
6,945 Views
24 Pages

Glycoprotein G-protein Coupled Receptors in Disease: Luteinizing Hormone Receptors and Follicle Stimulating Hormone Receptors

  • Duaa Althumairy,
  • Xiaoping Zhang,
  • Nicholas Baez,
  • George Barisas,
  • Deborah A. Roess,
  • George R. Bousfield and
  • Debbie C. Crans

15 September 2020

Signal transduction by luteinizing hormone receptors (LHRs) and follicle-stimulating hormone receptors (FSHRs) is essential for the successful reproduction of human beings. Both receptors and the thyroid-stimulating hormone receptor are members of a...

  • Brief Report
  • Open Access
11 Citations
3,361 Views
11 Pages

Evaluation of Plasma Circulating Cell Free DNA Concentration and Integrity in Patients with Prostate Cancer in Jamaica: A Preliminary Study

  • Andrew Condappa,
  • Donovan McGrowder,
  • William Aiken,
  • Wayne McLaughlin and
  • Maxine Gossell-Williams

7 September 2020

Background: Cell free circulating DNA (cfcDNA) is a promising diagnostic tool for prostate cancer (PCa). This study aimed to measure the cfcDNA concentration and integrity in PCa patients using quantitative polymerase chain reaction (qPCR) analysis....

  • Review
  • Open Access
20 Citations
7,747 Views
26 Pages

30 August 2020

There is an increasing interest in the intestinal microbiota as a critical regulator of the development and function of the immune, nervous, and endocrine systems. Experimental work in animal models has provided the foundation for clinical studies to...

  • Review
  • Open Access
11 Citations
3,536 Views
9 Pages

Pulmonary Infectious Complications in Children with Hematologic Malignancies and Chemotherapy-Induced Neutropenia

  • Aikaterini Voulgaridou,
  • Kleoniki I. Athanasiadou,
  • Eftychia Athanasiadou,
  • Emmanuel Roilides and
  • Evgenia Papakonstantinou

19 August 2020

Infections frequently complicate the treatment course in children with hematologic malignancies undergoing chemotherapy. Febrile neutropenia (FN) remains a major cause of hospital admissions in this population, and respiratory tract is often proven t...

  • Article
  • Open Access
1 Citations
4,764 Views
8 Pages

Fosfomycin, Applying Known Methods and Remedies to A New Era

  • Viviana Albán M.,
  • Estefanía Mariño-Brito,
  • Fernando Villavicencio,
  • Carolina Satán,
  • José E. Villacís and
  • Mónica C. Gestal

The exponential increase in the numbers of isolates of Carbapenem-Resistant Enterobacteriaceae (CRE) creates the need for using novel therapeutic approaches to save the lives of patients. Fosfomycin has long been considered a rational option for the...

  • Article
  • Open Access
16 Citations
7,067 Views
16 Pages

Perceptions on Adherence to Dietary Prescriptions for Adults with Chronic Kidney Disease on Hemodialysis: A Qualitative Study

  • Rose Okoyo Opiyo,
  • Susan Akoth Nyawade,
  • Michael McCaul,
  • Peter Suwirakwenda Nyasulu,
  • Daniel Bolo Lango,
  • Anthony Jude Omolo Were,
  • Esther Clyde Nabakwe,
  • Zipporah Nekesa Bukania and
  • Joyce Muhenge Olenja

Diet is one of the modifiable lifestyle factors in management of kidney disease. We explored perceptions on adherence to dietary prescriptions for adults with chronic kidney disease on hemodialysis. This was a qualitative descriptive study. Participa...

  • Review
  • Open Access
20 Citations
12,429 Views
30 Pages

The outbreak of novel coronavirus disease (2019-nCoV or COVID-19) is responsible for severe health emergency throughout the world. The attack of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is found to be responsible for COVID-19. The...

  • Article
  • Open Access
38 Citations
4,772 Views
10 Pages

Impact of Acute Kidney Injury on Outcomes of Hospitalizations for Heat Stroke in the United States

  • Charat Thongprayoon,
  • Fawad Qureshi,
  • Tananchai Petnak,
  • Wisit Cheungpasitporn,
  • Api Chewcharat,
  • Liam D. Cato,
  • Boonphiphop Boonpheng,
  • Tarun Bathini,
  • Panupong Hansrivijit and
  • Saraschandra Vallabhajosyula
  • + 1 author

This study aims to evaluate the risk factors and the association of acute kidney injury with treatments, complications, outcomes, and resource utilization in patients hospitalized for heat stroke in the United States. Hospitalized patients from years...

  • Brief Report
  • Open Access
13 Citations
5,707 Views
5 Pages

Impact of Obesity on Ceftriaxone Efficacy

  • Katie E. Barber,
  • J. Taylor Loper,
  • Austin R. Morrison,
  • Kayla R. Stover and
  • Jamie L. Wagner

Background: Ceftriaxone has standard, set dosing regimens that may not achieve adequate serum concentrations in obese patients compared to non-obese patients. The purpose of this study was to evaluate the effect of obesity on ceftriaxone efficacy whe...

  • Feature Paper
  • Article
  • Open Access
11 Citations
16,358 Views
11 Pages

Short-Term Effect of a New Oral Sodium Hyaluronate Formulation on Knee Osteoarthritis: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial

  • Arrigo F. G. Cicero,
  • Nicolò Girolimetto,
  • Crescenzio Bentivenga,
  • Elisa Grandi,
  • Federica Fogacci and
  • Claudio Borghi

Objective: the aim of this pilot study was to test the short-term effect of oral supplementation with a sodium hyaluronate with a large spectrum of molecular weights (FS-HA®) on the symptoms and functionality of knee osteoarthritis (OA). Methods:...

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Diseases - ISSN 2079-9721