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Diseases, Volume 8, Issue 4

December 2020 - 12 articles

Cover Story: Sickle cell disease (SCD) is a group of life-threatening inherited disorders with multiple aspects, such as public health and clinical aspects. Textual data structures (such as words, sentences, and data tables) in expert/evidence reports on SCD management present prospects for constructing qualitative and quantitative datasets. We have constructed datasets and associated interactive visualizations to conduct interactive analytics of textual data structures on public health and clinical aspects of sickle cell disease. Our report presents unique data products (https://bit.ly/scddata) that include landmark expert reports from the year 2020. Interactive analytics can support individual and team expertise for effective community-based research and practice on SCD. View this paper.
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Articles (12)

  • Communication
  • Open Access
6,015 Views
7 Pages

Use of Population-Based Health Informatics Research to Improve Care for Patients with Cardiovascular Diseases

  • Ify R. Mordi,
  • Magalie Guignard-Duff,
  • Christopher Hall,
  • Benjamin Jaa Ming New and
  • Chim C. Lang

17 December 2020

There are common clinical scenarios in chronic heart disease where no randomized controlled data exist to guide management, and it is likely that well-designed observational studies will have to be used to inform clinical practice. Showing the clinic...

  • Review
  • Open Access
16 Citations
6,923 Views
10 Pages

Fertility and Reproduction after Recovery from Anorexia Nervosa: A Systematic Review and Meta-Analysis of Long-Term Follow-Up Studies

  • Rayane Chaer,
  • Nour Nakouzi,
  • Leila Itani,
  • Hana Tannir,
  • Dima Kreidieh,
  • Dana El Masri and
  • Marwan El Ghoch

16 December 2020

Reproductive health is compromised during anorexia nervosa (AN). However, it is still unclear whether this medical complication is reversible after recovery from AN. The purpose of this paper was to conduct a systematic review of the major reproducti...

  • Communication
  • Open Access
2 Citations
3,428 Views
5 Pages

10 December 2020

Many Geriatric Health Services Facilities in Japan may have continued outpatient rehabilitation by taking measures against infection even during the state of emergency caused by Coronavirus disease 2019 (COVID-19). The present study aimed to determin...

  • Review
  • Open Access
60 Citations
37,176 Views
15 Pages

Can Melatonin Be a Potential “Silver Bullet” in Treating COVID-19 Patients?

  • Daniel P. Cardinali,
  • Gregory M. Brown and
  • Seithikurippu R. Pandi-Perumal

26 November 2020

The therapeutic potential of melatonin as a chronobiotic cytoprotective agent to counteract the consequences of COVID-19 infections has been advocated. Because of its wide-ranging effects as an antioxidant, anti-inflammatory, and immunomodulatory com...

  • Article
  • Open Access
3 Citations
3,255 Views
9 Pages

The Emotion of Disgust among Medical and Psychology Students

  • Artemios Pehlivanidis,
  • Niki Pehlivanidi,
  • Katerina Papanikolaou,
  • Vassileios Mantas,
  • Elpida Bertou,
  • Theodoros Chalimourdas,
  • Vana Sypsa and
  • Charalambos Papageorgiou

15 November 2020

The emotion of disgust evolved as a way to protect oneself from illness and is associated with aspects of disease avoidance. Disgust Scale–Revised (DS-R) (Olatunji et al., 2008) measures the disgust propensity of three kinds of disgust (core, a...

  • Feature Paper
  • Review
  • Open Access
24 Citations
7,441 Views
17 Pages

Precision Medicine in Rare Diseases

  • Irene Villalón-García,
  • Mónica Álvarez-Córdoba,
  • Juan Miguel Suárez-Rivero,
  • Suleva Povea-Cabello,
  • Marta Talaverón-Rey,
  • Alejandra Suárez-Carrillo,
  • Manuel Munuera-Cabeza and
  • José Antonio Sánchez-Alcázar

13 November 2020

Rare diseases are those that have a low prevalence in the population (less than 5 individuals per 10,000 inhabitants). However, infrequent pathologies affect a large number of people, since according to the World Health Organization (WHO), there are...

  • Review
  • Open Access
12 Citations
4,848 Views
22 Pages

10 November 2020

Background and Aim: Although constitutional and respiratory symptoms such as cough and fever are the most common symptoms in patients infected with COVID-19, gastrointestinal (GI) tract involvement has been observed by endoscopic biopsies. Multiple G...

  • Brief Report
  • Open Access
28 Citations
4,983 Views
8 Pages

Incidence of Myocardial Injury in COVID-19-Infected Patients: A Systematic Review and Meta-Analysis

  • Narut Prasitlumkum,
  • Ronpichai Chokesuwattanaskul,
  • Charat Thongprayoon,
  • Tarun Bathini,
  • Saraschandra Vallabhajosyula and
  • Wisit Cheungpasitporn

27 October 2020

Introduction: The incidence of acute myocardial injury (AMI) among Coronavirus Disease 19 (COVID-19)-infected patients remain unclear. We aimed to conduct a systematic review and meta-analysis to further explore the incidence AMI in these patients. M...

  • Article
  • Open Access
4 Citations
4,447 Views
22 Pages

Integrating Datasets on Public Health and Clinical Aspects of Sickle Cell Disease for Effective Community-Based Research and Practice

  • Raphael D. Isokpehi,
  • Chomel P. Johnson,
  • Ashley N. Tucker,
  • Aakriti Gautam,
  • Taylor J. Brooks,
  • Matilda O. Johnson,
  • Thometta Cozart and
  • Deanna J. Wathington

26 October 2020

Sickle cell disease (SCD) is a genetic disease that has multiple aspects including public health and clinical aspects. The goals of the research study were to (1) understand the public health aspects of sickle cell disease, and (2) understand the ove...

  • Article
  • Open Access
1 Citations
3,235 Views
11 Pages

20 October 2020

Ever since the index case of COVID-19 was announced in Nigeria, the number of confirmed cases has gradually increased to 46,140 (about 4.5% of total confirmed cases in Africa) as the time of writing this article. This seemingly low number of confirme...

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Diseases - ISSN 2079-9721