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Journal of Functional Biomaterials, Volume 14, Issue 2

February 2023 - 67 articles

Cover Story: Natural hydrogels have been a great matter of interest in recent years. Their biocompatibility, biodegradability, and low toxicity allow them to be used for different biomedical applications, including drug delivery systems, tissue regeneration, 3D printing, and recently, as systems for cancer prevention, diagnosis, and treatment. Polysaccharides represent the polymer group with the longest-standing as well as the widest-ranging experience in the biomedical field. The presence of multi-functional groups in their backbone permits easy chemical modifications to obtain polysaccharide derivatives with unique properties. This review explores different natural hydrogels based on polysaccharides and discusses their application as drug delivery systems with a special focus on cancer treatment. View this paper
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Articles (67)

  • Perspective
  • Open Access
17 Citations
6,676 Views
18 Pages

19 February 2023

Membrane fusion is one of the key phenomena in the living cell for maintaining the basic function of life. Extracellular vesicles (EVs) have the ability to transfer information between cells through plasma membrane fusion, making them a promising too...

  • Article
  • Open Access
15 Citations
3,695 Views
23 Pages

One-Piece Zirconia Oral Implants for Single Tooth Replacement: Five-Year Results from a Prospective Cohort Study

  • Ralf-Joachim Kohal,
  • Felix Burkhardt,
  • Jerome Chevalier,
  • Sebastian Berthold Maximilian Patzelt and
  • Frank Butz

19 February 2023

The intention of this 5-year prospective cohort investigation was to clinically and radiographically investigate the outcomes of a one-piece zirconia implant system for single tooth replacement. Sixty-five patients received a total of 66 single-tooth...

  • Review
  • Open Access
51 Citations
5,519 Views
26 Pages

Combinational System of Lipid-Based Nanocarriers and Biodegradable Polymers for Wound Healing: An Updated Review

  • Bahareh Farasati Far,
  • Mohammad Reza Naimi-Jamal,
  • Meysam Sedaghat,
  • Alireza Hoseini,
  • Negar Mohammadi and
  • Mahdi Bodaghi

18 February 2023

Skin wounds have imposed serious socioeconomic burdens on healthcare providers and patients. There are just more than 25,000 burn injury-related deaths reported each year. Conventional treatments do not often allow the re-establishment of the functio...

  • Article
  • Open Access
5 Citations
8,697 Views
15 Pages

Effectiveness of Hyaluronic Acid Gel Injection with and without PRGF for Management of Interdental Papillary Loss: A Randomized Clinical Trial

  • Aishwarya Bal,
  • Saurav Panda,
  • Rinkee Mohanty,
  • Anurag Satpathy,
  • Rashmita Nayak,
  • Margherita Tumedei,
  • Francesca Argenta,
  • Gianluca Colapinto,
  • Massimo Del Fabbro and
  • Marco Annunziata

18 February 2023

Background: To evaluate the effectiveness of hyaluronic acid (HA) gel injection with and without plasma rich in growth factors (PRGF) for the management of interdental papillary loss. Methods: A single blinded randomized clinical trial was carried ou...

  • Article
  • Open Access
6 Citations
2,756 Views
12 Pages

17 February 2023

Porous titanium interbody scaffolds are growing in popularity due to their appealing advantages for bone ingrowth. This study aimed to investigate the biomechanical effects of scaffold materials in both normal and osteoporotic lumbar spines using a f...

  • Article
  • Open Access
15 Citations
3,540 Views
19 Pages

Synthesis and Spectral Characterisation of Fabricated Cerium-Doped Magnesium Oxide Nanoparticles: Evaluation of the Antimicrobial Potential and Its Membranolytic Activity through Large Unilamellar Vesicles

  • Ashapurna Khatua,
  • Kajal Kumari,
  • Deepak Khatak,
  • Annesha Roy,
  • Neelima Bhatt,
  • Bernard Paul,
  • Aparupa Naik,
  • Amiya Kumar Patel,
  • Uttam Kumar Panigrahi and
  • Santosh Kumar Sahu
  • + 2 authors

17 February 2023

Considerable attention has been given to Magnesium oxide nanoparticles lately due to their antimicrobial potential, low toxicity to humans, high thermal stability, biocompatibility, and low cost of production. However, their successful transformation...

  • Article
  • Open Access
19 Citations
3,913 Views
20 Pages

Effectiveness of BMP-2 and PDGF-BB Adsorption onto a Collagen/Collagen-Magnesium-Hydroxyapatite Scaffold in Weight-Bearing and Non-Weight-Bearing Osteochondral Defect Bone Repair: In Vitro, Ex Vivo and In Vivo Evaluation

  • Jietao Xu,
  • Shorouk Fahmy-Garcia,
  • Marinus A. Wesdorp,
  • Nicole Kops,
  • Lucia Forte,
  • Claudio De Luca,
  • Massimiliano Maraglino Misciagna,
  • Laura Dolcini,
  • Giuseppe Filardo and
  • Margot Labberté
  • + 7 authors

16 February 2023

Despite promising clinical results in osteochondral defect repair, a recently developed bi-layered collagen/collagen-magnesium-hydroxyapatite scaffold has demonstrated less optimal subchondral bone repair. This study aimed to improve the bone repair...

  • Article
  • Open Access
5 Citations
3,568 Views
10 Pages

Evaluation of Enamel Surfaces after Different Techniques of Interproximal Enamel Reduction

  • Francesca Silvestrini Biavati,
  • Viola Schiaffino,
  • Antonio Signore,
  • Nicola De Angelis,
  • Valentina Lanteri and
  • Alessandro Ugolini

16 February 2023

According to the literature, interproximal enamel reduction (IER) has become a consolidated technique used in orthodontic treatments to gain space in particular situations such as dental crowding, non-extractive therapies, tooth-size discrepancies, a...

  • Article
  • Open Access
28 Citations
3,657 Views
11 Pages

Fluoride and Calcium Release from Alkasite and Glass Ionomer Restorative Dental Materials: In Vitro Study

  • Alessandro Di Lauro,
  • Fabiana Di Duca,
  • Paolo Montuori,
  • Amanda Maria de Oliveira Dal Piva,
  • João Paulo Mendes Tribst,
  • Alexandre Luiz Souto Borges and
  • Pietro Ausiello

15 February 2023

This study evaluated the effect of pH and temperature on the ion (F− and Ca2+) release of a resin-based material containing alkaline fillers and a self-setting high-viscous glass ionomer cement. Disks were prepared according to manufacturers&rs...

  • Article
  • Open Access
8 Citations
4,545 Views
16 Pages

Structural Integrity of Anterior Ceramic Resin-Bonded Fixed Partial Denture: A Finite Element Analysis Study

  • Mas Linda Mohd Osman,
  • Tong Wah Lim,
  • Hung-Chih Chang,
  • Amir Radzi Ab Ghani,
  • James Kit Hon Tsoi and
  • Siti Mariam Ab Ghani

15 February 2023

This study was conducted as a means to evaluate the stress distribution patterns of anterior ceramic resin-bonded fixed partial dentures derived from different materials and numerous connector designs that had various loading conditions imposed onto...

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J. Funct. Biomater. - ISSN 2079-4983Creative Common CC BY license