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Journal of Functional Biomaterials, Volume 14, Issue 3

March 2023 - 56 articles

Cover Story: Light-cured dental composites are used to fill tooth decays in routine dental practice. This study demonstrated the following: 1) Increased cure time mitigates dental composite cytotoxicity only under certain conditions. 2) Nonetheless, the adverse effect of composites is significant to human gingival fibroblasts compared to that of pre-cured PMMA, regardless of the composite material being close to or far from the gingival tissue. 3) Under some conditions, the benefit of longer cure time is negated or reversed. These findings are valuable when performing dental restorative procedures and provide novel insights into understanding the polymerization behavior of composites and improving the material. View this paper
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Articles (56)

  • Article
  • Open Access
5 Citations
2,782 Views
13 Pages

Can Zeolite-Supporting Acridines Boost Their Anticancer Performance?

  • Maja Ranković,
  • Anka Jevremović,
  • Aleksandra Janošević Ležaić,
  • Aleksandar Arsenijević,
  • Jelena Rupar,
  • Vladimir Dobričić,
  • Bojana Nedić Vasiljević,
  • Nemanja Gavrilov,
  • Danica Bajuk-Bogdanović and
  • Maja Milojević-Rakić

Acridine and its derivatives (9-chloroacridine and 9-aminoacridine) are investigated here, supported on FAU type zeolite Y, as a delivery system of anticancer agents. FTIR/Raman spectroscopy and electron microscopy revealed successful drug loading on...

  • Article
  • Open Access
5 Citations
3,774 Views
17 Pages

A wide variety of titanium (Ti) alloy dental implant systems are available and as a result, choosing the correct system has become a challenge. Cleanliness of the dental implant surface affects osseointegration but surface cleanliness may be jeopardi...

  • Article
  • Open Access
5 Citations
2,496 Views
12 Pages

Fluoride Retention in Root Dentin following Surface Coating Material Application

  • Katsushi Okuyama,
  • Yasuhiro Matsuda,
  • Hiroko Yamamoto,
  • Kohtaku Suzuki,
  • Kohei Shintani,
  • Takashi Saito,
  • Mikako Hayashi and
  • Yukimichi Tamaki

This study aimed to use an in-air micro-particle-induced X-ray/gamma emission (in-air µPIXE/PIGE) system to evaluate tooth-bound fluoride (T-F) in dentin following the application of fluoride-containing tooth-coating materials. Three fluoride-c...

  • Article
  • Open Access
3 Citations
3,200 Views
14 Pages

Improving Bone Formation by Guided Bone Regeneration Using a Collagen Membrane with rhBMP-2: A Novel Concept

  • Narae Jung,
  • Jaehan Park,
  • Sang-Hyun Park,
  • Seunghan Oh,
  • Sungtae Kim,
  • Sung-Won Cho,
  • Jong-Eun Kim,
  • Hong Seok Moon and
  • Young-Bum Park

We examined whether recombinant human bone morphogenetic protein-2 (rhBMP-2) when applied to collagen membranes, would reinforce them during guided bone regeneration. Four critical cranial bone defects were created and treated in 30 New Zealand white...

  • Review
  • Open Access
9 Citations
3,494 Views
20 Pages

Physical stimuli play an important role in one tissue engineering. Mechanical stimuli, such as ultrasound with cyclic loading, are widely used to promote bone osteogenesis; however, the inflammatory response under physical stimuli has not been well s...

  • Article
  • Open Access
18 Citations
4,016 Views
16 Pages

Long-Term Degradation Assessment of a Polyurethane-Based Surgical Adhesive—Assessment and Critical Consideration of Preclinical In Vitro and In Vivo Testing

  • Lisanne Bremer,
  • Kerstin Hagemeister,
  • Michaela Moss,
  • Lisa Ernst,
  • René H. Tolba,
  • Stefan Jockenhoevel and
  • Christian Apel

Tissue adhesives constitute a great possibility to improve conventional wound closure. In contrast to sutures, they enable nearly immediate hemostasis and can prevent fluid or air leaks. In the present study, a poly(ester)urethane-based adhesive was...

  • Article
  • Open Access
11 Citations
2,765 Views
24 Pages

Functionalized Halloysite Nanotubes as Potential Drug Carriers

  • Ewa Stodolak-Zych,
  • Alicja Rapacz-Kmita,
  • Marcin Gajek,
  • Agnieszka Różycka,
  • Magdalena Dudek and
  • Stanisława Kluska

The aim of the work was to examine the possibility of using modified halloysite nanotubes as a gentamicin carrier and to determine the usefulness of the modification in terms of the effect on the amount of the drug attached, its release time, but als...

  • Review
  • Open Access
25 Citations
5,476 Views
25 Pages

Doped Carbon Quantum Dots Reinforced Hydrogels for Sustained Delivery of Molecular Cargo

  • Shweta Kanungo,
  • Neeta Gupta,
  • Reena Rawat,
  • Bhawana Jain,
  • Aruna Solanki,
  • Ashutosh Panday,
  • P. Das and
  • S. Ganguly

Hydrogels have emerged as important soft materials with numerous applications in fields including biomedicine, biomimetic smart materials, and electrochemistry. Because of their outstanding photo-physical properties and prolonged colloidal stability,...

  • Article
  • Open Access
15 Citations
3,763 Views
13 Pages

Intermittent Exposure to a 16 Hz Extremely Low Frequency Pulsed Electromagnetic Field Promotes Osteogenesis In Vitro through Activating Piezo 1-Induced Ca2+ Influx in Osteoprogenitor Cells

  • Yangmengfan Chen,
  • Benedikt J. Braun,
  • Maximilian M. Menger,
  • Michael Ronniger,
  • Karsten Falldorf,
  • Tina Histing,
  • Andreas K. Nussler and
  • Sabrina Ehnert

Exposure to extremely low frequency pulsed electromagnetic fields (ELF-PEMF) is supposed to simulate local EMF generated during mechanical stimulation of bone and may therefore be used to improve bone regeneration. This study aimed at optimizing the...

  • Article
  • Open Access
29 Citations
4,368 Views
16 Pages

The Use of Premixed Calcium Silicate Bioceramic Sealer with Warm Carrier-Based Technique: A 2-Year Study for Patients Treated in a Master Program

  • Fausto Zamparini,
  • Andrea Spinelli,
  • Filippo Cardinali,
  • Pietro Ausiello,
  • Maria Giovanna Gandolfi and
  • Carlo Prati

Background: Recently several calcium silicate flowable sealers have been introduced as endodontic materials for the root canal. This clinical study tested the use of a new premixed calcium silicate bioceramic sealer in association with the Thermafil...

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J. Funct. Biomater. - ISSN 2079-4983