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Medical Sciences, Volume 11, Issue 1

March 2023 - 24 articles

Cover Story: Artificial intelligence is developing at an astounding pace, with recent emerging technology such as ChatGPT opening a world of new possibilities. In healthcare, coronary artery disease remains the biggest killer worldwide and hence represents a critical field where AI can offer key solutions. Through its ability to process vast amounts of data and learn from algorithms, AI has the huge potential to improve risk prediction using cardiac imaging, reduce human error, and shorten patient waiting times. In this paper, we discuss the applications, implications, opportunities, and challenges that are likely to arise as a result of using AI in cardiology, focusing mainly on cardiac imaging. View this paper
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Articles (24)

  • Article
  • Open Access
2 Citations
3,258 Views
11 Pages

Thiotepa, Busulfan, Cyclophosphamide: Effective but Toxic Conditioning Regimen Prior to Autologous Hematopoietic Stem Cell Transplantation in Central Nervous System Lymphoma

  • Lebon Delphine,
  • Debureaux Pierre-Edouard,
  • Royer Bruno,
  • Gruson Bérengère,
  • Joris Magalie,
  • Votte Patrick,
  • Marolleau Jean-Pierre and
  • Morel Pierre

29 January 2023

In primary central nervous system lymphoma, two-year progression-free survival rates of up to 63 percent have been reported for first-line autologous stem cell transplantation after conditioning with the thiotepa busulfan cyclophosphamide regimen. Ho...

  • Article
  • Open Access
4 Citations
3,862 Views
12 Pages

The Importance of Mitral Valve Prolapse Doming Volume in the Assessment of Left Ventricular Stroke Volume with Cardiac MRI

  • Rui Li,
  • Hosamadin Assadi,
  • Gareth Matthews,
  • Zia Mehmood,
  • Ciaran Grafton-Clarke,
  • Bahman Kasmai,
  • David Hewson,
  • Richard Greenwood,
  • Hilmar Spohr and
  • Liang Zhong
  • + 13 authors

24 January 2023

There remains a debate whether the ventricular volume within prolapsing mitral valve (MV) leaflets should be included in the left ventricular (LV) end-systolic volume, and therefore factored in LV stroke volume (SV), in cardiac magnetic resonance (CM...

  • Article
  • Open Access
7 Citations
2,974 Views
9 Pages

Free Flaps for Skin and Soft Tissue Reconstruction in the Elderly Patient: Indication or Contraindication

  • Heiko Sorg,
  • Christian G. G. Sorg,
  • Daniel J. Tilkorn,
  • Simon Thönnes,
  • Rees Karimo and
  • Jörg Hauser

21 January 2023

Background: Increased lifespan and the improvement of medical treatment have given rise to research in reconstructive procedures in elderly patients. Higher postoperative complication rates, longer rehabilitation, and surgical difficulties remain a p...

  • Perspective
  • Open Access
46 Citations
8,881 Views
13 Pages

17 January 2023

Electrical stimulation of the cell can have a number of different effects depending on the type of cell being stimulated. In general, electrical stimulation can cause the cell to become more active, increase its metabolism, and change its gene expres...

  • Review
  • Open Access
10 Citations
3,996 Views
9 Pages

Melatonin as a Repurposed Drug for Melanoma Treatment

  • Rachana Pathipaka,
  • Anita Thyagarajan and
  • Ravi P. Sahu

14 January 2023

Melanoma is the most aggressive type of skin cancer, with a greater risk of metastasis and a higher prevalence and mortality rate. This cancer type has been demonstrated to develop resistance to the known treatment options such as conventional therap...

  • Review
  • Open Access
8 Citations
3,981 Views
12 Pages

4 January 2023

In the last ten years, liquid biopsy has been slowly joining the traditional invasive techniques for the diagnosis and monitoring of tumors. Liquid biopsies allow easy repeated sampling of blood, reflect the tumor scenario, and make personalized ther...

  • Article
  • Open Access
3 Citations
3,087 Views
14 Pages

29 December 2022

Background: Knowledge about the occurrence of processes such as proliferation, apoptosis and angiogenesis in healthy lung tissues with different bronchial epitheliums is limited, and further exploration can contribute to a better understanding of the...

  • Review
  • Open Access
3 Citations
3,786 Views
16 Pages

The Role of Extracellular Vesicles in Diseases of the Ear, Nose, and Throat

  • Jonathan M Carnino,
  • Steven Miyawaki and
  • Sanjeev Rampam

28 December 2022

Extracellular vesicles (EVs) are membranous nanoparticles produced by most cell types into the extracellular space and play an important role in cell-to-cell communication. Historically, EVs were categorized based on their methods of biogenesis and s...

  • Article
  • Open Access
1 Citations
2,700 Views
9 Pages

The ESCRT-III Protein Chmp1 Regulates Lipid Storage in the Drosophila Fat Body

  • Austin M. Fruin,
  • Kelly E. Leon and
  • Justin R. DiAngelo

26 December 2022

Defects in how excess nutrients are stored as triglycerides can result in several diseases including obesity, heart disease, and diabetes. Understanding the genes responsible for normal lipid homeostasis will help understand the pathogenesis of these...

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Med. Sci. - ISSN 2076-3271