Animals, Volume 14, Issue 11
2024 June-1 - 198 articles
Cover Story: The use of saliva for the measurement of biomarkers is growing in pigs due to its ease of collection and non-invasive nature. Cystatin C, ammonia, and bicarbonate have been reported to be biomarkers of sepsis and inflammation in humans, but little is known about their role in pigs. The objective of the following report was to validate commercially available assays for the measurement of these three biomarkers in the saliva of pigs and study their variations in a septic disease such as Streptococcus suis (S. suis) infection. The assays showed adequate analytical precision and accuracy. Pigs with S. suis infection had higher mean concentrations of cystatin and ammonia and lower concentrations of bicarbonate in their saliva than healthy pigs. Based on the above results, cystatin C, ammonia, and bicarbonate can be noted as potential biomarkers in the saliva of pigs. View this paper - Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
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