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Pathogens, Volume 6, Issue 2

2017 June - 13 articles

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Articles (13)

  • Article
  • Open Access
14 Citations
7,391 Views
11 Pages

IgG Avidity Test in Congenital Toxoplasmosis Diagnoses in Newborns

  • Zulmirene Cardoso Fonseca,
  • Isolina Maria Xavier Rodrigues,
  • Natália Cruz e Melo,
  • Juliana Boaventura Avelar and ,
  • Ana Maria Castro and
  • Mariza Martins Avelino
  • + 1 author+ 0 author

The goal of this study was to investigate the importance of IgG avidity testing in newborns (NBs) diagnosed with early congenital toxoplasmosis. We collected samples from 88 puerperae infected by Toxoplasma gondii (T. gondii) and their NBs (48 acutel...

(This article belongs to the Special Issue Toxoplasma gondii Infection)
  • Review
  • Open Access
13 Citations
7,326 Views
13 Pages

Influenza A viruses (IAV) continually evolve and have the capacity to cause global pandemics. Because IAV represents an ongoing threat, identifying novel therapies and host innate immune factors that contribute to IAV pathogenesis is of considerable...

  • Feature Paper
  • Article
  • Open Access
  • Best Paper Award
47 Citations
8,994 Views
15 Pages

Modeling HSV-1 Latency in Human Embryonic Stem Cell-Derived Neurons

  • Aldo Pourchet,
  • Aram S. Modrek,
  • Dimitris G. Placantonakis,
  • Ian Mohr and
  • Angus C. Wilson

Herpes simplex virus 1 (HSV-1) uses latency in peripheral ganglia to persist in its human host, however, recurrent reactivation from this reservoir can cause debilitating and potentially life-threatening disease. Most studies of latency use live-anim...

(This article belongs to the Special Issue Herpesviruses)
  • Article
  • Open Access
10 Citations
7,025 Views
10 Pages

Molecular Typing of Staphylococcus aureus Isolated from Patients with Autosomal Dominant Hyper IgE Syndrome

  • Inka Sastalla,
  • Kelli W. Williams,
  • Erik D. Anderson,
  • Ian A. Myles and ,
  • Jensen D. Reckhow,
  • Marlene Espinoza-Moraga,
  • Alexandra F. Freeman and
  • Sandip K. Datta
  • + 3 authors+ 0 author

Autosomal dominant hyper IgE syndrome (AD-HIES) is a primary immunodeficiency caused by a loss-of-function mutation in the Signal Transducer and Activator of Transcription 3 (STAT3). This immune disorder is clinically characterized by increased susce...

  • Feature Paper
  • Article
  • Open Access
27 Citations
7,187 Views
12 Pages

Antibiotic Resistance and Virulence Phenotypes of Recent Bacterial Strains Isolated from Urinary Tract Infections in Elderly Patients with Prostatic Disease

  • Cristina Delcaru,
  • Paulina Podgoreanu,
  • Ionela Alexandru,
  • Nela Popescu and ,
  • Luminiţa Măruţescu,
  • Coralia Bleotu,
  • George Dan Mogoşanu,
  • Mariana Carmen Chifiriuc,
  • Marinela Gluck and
  • Veronica Lazăr
  • + 5 authors+ 0 author

Acute bacterial prostatitis is one of the frequent complications of urinary tract infection (UTI). From the approximately 10% of men having prostatitis, 7% experience a bacterial prostatitis. The purpose of this study was to investigate the prevalenc...

  • Communication
  • Open Access
74 Citations
13,403 Views
7 Pages

Toxoplasma gondii in the Food Supply

  • Malik A. Hussain,
  • Victoria Stitt,
  • Elizabeth A. Szabo and
  • Bruce Nelan

Toxoplasmosis is caused by infection with the protozoan parasite Toxoplasma gondii. Infections are usually either asymptomatic or develop mild symptoms that are self-limited, but infections in immunosuppressed persons can be severe. Infections in pre...

(This article belongs to the Special Issue Toxoplasma gondii Infection)
  • Article
  • Open Access
13 Citations
5,321 Views
10 Pages

Bacteria of genus Achromobacter are emerging pathogens in cystic fibrosis (CF) capable of biofilm formation and development of antimicrobial resistance. Evolutionary adaptions in the transition from primary to chronic infection were assessed by trans...

  • Feature Paper
  • Article
  • Open Access
9 Citations
5,387 Views
11 Pages

Enterotoxigenic Escherichia coli Flagellin Inhibits TNF-Induced NF-κB Activation in Intestinal Epithelial Cells

  • Gaochan Wang,
  • Brian V. Geisbrecht,
  • Christian Rueter and
  • Philip R. Hardwidge

Enterotoxigenic Escherichia coli (ETEC) causes childhood diarrhea in developing countries. ETEC strains produce the heat-labile enterotoxin (LT) and/or heat-stable enterotoxins (ST) and encode a diverse set of colonization factors used for adherence...

  • Review
  • Open Access
72 Citations
17,992 Views
13 Pages

Although the parasite Toxoplasma gondii is one of the most pervasive neurotropic pathogens in the world, the host-parasite interactions during CNS infection and the consequences of neurological infection are just beginning to be unraveled. The chroni...

(This article belongs to the Special Issue Toxoplasma gondii Infection)
  • Review
  • Open Access
11 Citations
7,439 Views
24 Pages

Subverting Host Cell P21-Activated Kinase: A Case of Convergent Evolution across Pathogens

  • Simona John Von Freyend,
  • Terry Kwok-Schuelein,
  • Hans J. Netter,
  • Gholamreza Haqshenas and ,
  • Jean-Philippe Semblat and
  • Christian Doerig
  • + 1 author+ 0 author

Intracellular pathogens have evolved a wide range of strategies to not only escape from the immune systems of their hosts, but also to directly exploit a variety of host factors to facilitate the infection process. One such strategy is to subvert hos...

  • Article
  • Open Access
12 Citations
5,714 Views
22 Pages

Evaluation of the Immunomodulatory Properties of Streptococcus suis and Group B Streptococcus Capsular Polysaccharides on the Humoral Response

  • Cynthia Calzas,
  • Morgan Taillardet,
  • Insaf Salem Fourati,
  • David Roy and ,
  • Marcelo Gottschalk,
  • Hugo Soudeyns,
  • Thierry Defrance and
  • Mariela Segura
  • + 3 authors+ 0 author

Streptococcus suis and group B Streptococcus (GBS) are encapsulated streptococci causing septicemia and meningitis. Antibodies (Abs) against capsular polysaccharides (CPSs) have a crucial protective role, but the structure/composition of the CPS, inc...

(This article belongs to the Special Issue Streptococcus suis)
  • Article
  • Open Access
30 Citations
7,677 Views
12 Pages

Application of Hydrogen Peroxide as an Innovative Method of Treatment for Legionella Control in a Hospital Water Network

  • Beatrice Casini,
  • Francesco Aquino,
  • Michele Totaro,
  • Mario Miccoli and ,
  • Irio Galli,
  • Laura Manfredini,
  • Carlo Giustarini,
  • Anna Laura Costa,
  • Benedetta Tuvo and
  • Angelo Baggiani
  • + 7 authors+ 2 authors

Objectives: To evaluate the effectiveness of hydrogen peroxide (HP) use as a disinfectant in the hospital water network for the control of Legionella spp. colonization. Methods: Following the detection of high levels of Legionella contamination in a...

  • Review
  • Open Access
17 Citations
10,957 Views
15 Pages

Application of toxic antibacterial agents is considered necessary to control prevalent fresh water microorganisms that grow in evaporative cooling water systems, but can adversely affect the environment and human health. However, natural antibacteria...

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Pathogens - ISSN 2076-0817