You are currently viewing a new version of our website. To view the old version click .

Pathogens, Volume 11, Issue 7

July 2022 - 109 articles

Cover Story: Bovine tuberculosis is a global infectious threat, with under-performance of current diagnostics being a huge challenge. After screening nine host proteins, we found that IL-2, CXCL-9, IP-10 and CCL4, like IFNγ, were significantly elevated in PPDb stimulated blood supernatants of M. bovis challenged cattle. Further assessment in various animal cohorts revealed that PPDb-specific IL-2 and IP-10, like IFNγ, could discriminate naive from M. bovis challenged cattle; and CCL4 showed a DIVA potential, i.e., differentiating Infected from BCG vaccinates. Combined analysis accurately identified M. bovis infection with strong correlations among PPDb-specific IFNγ, IL-2 and IP-10 levels. We provide proof of concept for utilizing multiple biomarker signatures for discriminating cattle based on M. bovis infection or BCG vaccination status. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (109)

  • Review
  • Open Access
21 Citations
5,524 Views
16 Pages

Clostridioides difficile (C. difficile) represents a major health burden with substantial economic and clinical impact. Patients with inflammatory bowel diseases (IBD) were identified as a risk category for Clostridioides difficile infection (CDI). I...

  • Article
  • Open Access
5 Citations
2,702 Views
11 Pages

Experimental Infection of Mice and Ticks with the Human Isolate of Anaplasma phagocytophilum NY-18

  • Veronika Urbanová,
  • Eliška Kalinová,
  • Petr Kopáček and
  • Radek Šíma

Anaplasma phagocytophilum is the causative agent of tick-borne fever (TBF) and human granulocytic anaplasmosis (HGA) and is currently considered an emerging disease in the USA, Europe, and Asia. The increased prevalence of A. phagocytophilum as a hum...

  • Review
  • Open Access
9 Citations
4,731 Views
17 Pages

SUMOylation and Viral Infections of the Brain

  • Fergan Imbert,
  • Gabrielle Leavitt and
  • Dianne Langford

The small ubiquitin-like modifier (SUMO) system regulates numerous biological processes, including protein localization, stability and/or activity, transcription, and DNA repair. SUMO also plays critical roles in innate immunity and antiviral defense...

  • Article
  • Open Access
1 Citations
2,399 Views
12 Pages

Broad bean mottle bromovirus infects legume plants and is transmissible by insects. Several broad bean mottle virus (BBMV) isolates have been identified, including one in England (isolate Ba) and five in the Mediterranean countries: Libya (LyV), Moro...

  • Review
  • Open Access
23 Citations
3,845 Views
10 Pages

COVID-19 as Another Trigger for HBV Reactivation: Clinical Case and Review of Literature

  • Caterina Sagnelli,
  • Laura Montella,
  • Pierantonio Grimaldi,
  • Mariantonietta Pisaturo,
  • Loredana Alessio,
  • Stefania De Pascalis,
  • Evangelista Sagnelli and
  • Nicola Coppola

Universal hepatitis B virus (HBV) vaccination has been applied for years in most countries, but HBV infection remains an unresolved public health problem worldwide, with over one-third of the world’s population infected during their lifetime an...

  • Case Report
  • Open Access
3 Citations
2,531 Views
9 Pages

A Ruptured Left Gastric Artery Aneurysm That Neoplasticized during the Course of Coronavirus Disease 2019: A Case Report

  • Satoshi Ano,
  • Yuto Shinkura,
  • Tsuneaki Kenzaka,
  • Naoaki Kusunoki,
  • Satoru Kawasaki and
  • Hogara Nishisaki

Coronavirus disease 2019 (COVID-19) is an acute respiratory syndrome caused by SARS-CoV-2 and is known to cause respiratory and systemic symptoms. A SARS-CoV-2 infection is involved in aneurysm formation, enlargement, and rupture in medium-sized vess...

  • Article
  • Open Access
1 Citations
2,193 Views
9 Pages

The Biological Properties of the SARS-CoV-2 Cameroon Variant Spike: An Intermediate between the Alpha and Delta Variants

  • Stefano Pascarella,
  • Martina Bianchi,
  • Marta Giovanetti,
  • Domenico Benvenuto,
  • Alessandra Borsetti,
  • Roberto Cauda,
  • Antonio Cassone and
  • Massimo Ciccozzi

An analysis of the structural effect of the mutations of the B.1.640.2 (IHU) Spike Receptor Binding Domain (RBD) and N-terminal Domain (NTD) is reported along with a comparison with the sister lineage B.1.640.1. and a selection of variants of concern...

  • Article
  • Open Access
7 Citations
3,868 Views
9 Pages

In the Department of Parasitology and Mycology of Toulouse University Hospitals, patients presenting with common/covert toxocariasis were treated either with albendazole (39 cases) or with diethylcarbamazine (32 cases). Albendazole (ABZ) was given at...

  • Article
  • Open Access
6 Citations
3,421 Views
12 Pages

Survival of Campylobacter jejuni Co-Cultured with Salmonella spp. in Aerobic Conditions

  • Nagham Anis,
  • Laetitia Bonifait,
  • Ségolène Quesne,
  • Louise Baugé,
  • Wissam Yassine,
  • Muriel Guyard-Nicodème and
  • Marianne Chemaly

Campylobacter and Salmonella are responsible for the two major foodborne zoonotic diseases in Europe; poultry is the main infection source. Campylobacter cannot grow under aerobic conditions, but can show aerobic survival when co-cultured with other...

of 11

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Pathogens - ISSN 2076-0817Creative Common CC BY license