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Open AccessPerspective

Perspective of Molecular Diagnosis in Healthcare: From Barcode to Pattern Recognition

1
Department of Mechanical Engineering, Rochester Institute of Technology, Rochester, NY 14623, USA
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Precision Medicine and Public Healthcare Research Center, Tsinghua-Berkeley Shenzhen Institute, Shenzhen 518057, China
3
Department of QB3, University of California, Berkeley, CA 94720, USA
4
Department of Microsystems Engineering, Rochester Institute of Technology, NY 14623, USA
*
Authors to whom correspondence should be addressed.
Diagnostics 2019, 9(3), 75; https://doi.org/10.3390/diagnostics9030075
Received: 10 May 2019 / Revised: 8 July 2019 / Accepted: 10 July 2019 / Published: 13 July 2019
(This article belongs to the Section Novel Diagnostic Technologies and Devices)
Barcode technology has a broad spectrum of applications including healthcare, food security, and environmental monitoring, due to its ability to encode large amounts of information. With the rapid development of modern molecular research, barcodes are utilized as a reporter with different molecular combinations to label many biomolecular targets, including genomic and metabolic elements, even with multiplex targeting. Along with the advancements in barcoded bioassay, the improvements of various designs of barcode components, encoding and decoding strategies, and their portable adoption are indispensable in satisfying multiple purposes, such as medical confirmation and point-of-care (POC) testing. This perspective briefly discusses the current direction and progress of barcodes development and provides a hypothesis for barcoded bioassay in the near future. View Full-Text
Keywords: bioassay; barcode; fluorescence; DNA; RNA; gold nanoparticle; point-of-care (POC) bioassay; barcode; fluorescence; DNA; RNA; gold nanoparticle; point-of-care (POC)
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MDPI and ACS Style

He, Q.; Bao, M.; Hass, K.; Lin, W.; Qin, P.; Du, K. Perspective of Molecular Diagnosis in Healthcare: From Barcode to Pattern Recognition. Diagnostics 2019, 9, 75.

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