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Clinics and Practice, Volume 13, Issue 6

2023 December - 27 articles

Cover Story: Type 2 sodium-glucose cotransporter inhibitors (SGLT2i) are among the main therapeutic options for patients with chronic heart failure with reduced ejection fraction (HFrEF). The aim of this study was to evaluate the effects of SGLT2i on the echocardiographic parameters of left (LV) and right (RV) ventricular function among outpatients with a long history of HFrEF in optimized therapy. Our study shows that the addition of SGLT2i to the optimized therapy for HFrEF was associated with a significant improvement in both LV and RV function, thus highlighting a possible mechanism responsible for the benefit obtained with this class of drugs. View this paper
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Articles (27)

  • Article
  • Open Access
7 Citations
8,700 Views
12 Pages

Early Ambulation Shortened the Length of Hospital Stay in ICU Patients after Abdominal Surgery

  • Takashi Amari,
  • Daiki Matta,
  • Yukiho Makita,
  • Kyosuke Fukuda,
  • Hiroki Miyasaka,
  • Masami Kimura,
  • Yuta Sakamoto,
  • Satoshi Shimo and
  • Kenichiro Yamaguchi

18 December 2023

The optimal time to ambulation remains unclear for intensive care unit (ICU) patients following abdominal surgery. While previous studies have explored various mobilization techniques, a direct comparison between ambulation and other early mobilizati...

  • Article
  • Open Access
3,935 Views
9 Pages

Inducing Cough Reflex by Capsaicin Spray Stimulation in Patients with Acquired Brain Injury: A Preliminary Test and Proof of Concept

  • Luisa Spezzano,
  • Maria Daniela Cortese,
  • Maria Quintieri,
  • Loris Pignolo,
  • Paolo Tonin,
  • Francesca Lucia Lucca,
  • Francesco Tomaiuolo,
  • Rocco Salvatore Calabrò,
  • Giovanni Morone and
  • Antonio Cerasa

15 December 2023

Individuals with acquired brain injuries (ABIs) may experience various complications related to poor coughing or impaired cough reflex (including risk of aspiration pneumonia or respiratory infections). For this reason, cough assessment is an importa...

  • Case Report
  • Open Access
2 Citations
3,641 Views
10 Pages

Patient Presentations in a Community Pain Clinic after COVID-19 Infection or Vaccination: A Case-Series Approach

  • Angela Mailis,
  • Naomi Kupferstein,
  • Demetry Assimakopoulos,
  • Alex C. Mailis,
  • Sean Sutton and
  • Shehnaz Fatima Lakha

11 December 2023

Objectives: Early case report studies and anecdotes from patients, medical colleagues, and social media suggest that patients may present to chronic pain clinics with a number of complaints post COVID-19 infection or vaccination. The aim of this stud...

  • Review
  • Open Access
7 Citations
4,924 Views
16 Pages

Evaluating Nutritional Risk Factors for Delirium in Intensive-Care-Unit Patients: Present Insights and Prospects for Future Research

  • Arianna Piccirillo,
  • Francesco Perri,
  • Alessandro Vittori,
  • Franco Ionna,
  • Francesco Sabbatino,
  • Alessandro Ottaiano and
  • Marco Cascella

7 December 2023

Malnutrition, hypercatabolism, and metabolic changes are well-established risk factors for delirium in critically ill patients. Although the exact mechanisms are not fully understood, there is mounting evidence suggesting that malnutrition can cause...

  • Article
  • Open Access
3 Citations
2,075 Views
16 Pages

The Translation, Validation and Cultural Adaptation of Questionnaires Assessing the Quality of Life and Fatigue among Patients with Sjogren’s Syndrome for the Romanian Context

  • Denise-Ani Mardale,
  • Daniela Opriș-Belinski,
  • Violeta Bojincă,
  • Mihai Bojincă,
  • Emilia Păsăran,
  • Ioana Săulescu,
  • Florian Berghea and
  • Andra Bălănescu

5 December 2023

About 70% of patients with Sjogren’s syndrome suffer from fatigue, and for a large proportion of patients, it is one of the most noticeable manifestations leading to disability. To date, no study has been conducted in Romania to determine the q...

  • Case Report
  • Open Access
1 Citations
2,371 Views
12 Pages

30 November 2023

Non-small cell lung cancer (NSCLC) is the second most common cancer worldwide, resulting in 1.8 million deaths per year. Most patients are diagnosed with a metastatic disease. Brain metastases are one of the most common metastatic sites and are assoc...

  • Brief Report
  • Open Access
6 Citations
3,783 Views
8 Pages

Stress, Professional Burnout, and Employee Efficiency in the Greek National Organization for the Provision of Health Services

  • Alexandra Vlassi,
  • Evangelos Vitkos,
  • Despoina Michailidou,
  • Panagis M. Lykoudis,
  • Lambrini Kioroglou,
  • Athanassios Kyrgidis,
  • Ioannis Tilaveridis and
  • Theodoros Dardavesis

25 November 2023

Background: Workplace stress and burnout in the Greek healthcare system had been considered severe even before the high pressure of the COVID-19 pandemic. We aimed to investigate occupational quality of life and burnout effects on workplace errors am...

  • Article
  • Open Access
2 Citations
2,691 Views
9 Pages

24 November 2023

Background: With the growing incidence of breast cancer, efficient and correct staging is essential for further treatment decisions. Axillary ultrasound (US) remains the most common method for regional nodal involvement assessment. The aim of this st...

  • Article
  • Open Access
2 Citations
1,989 Views
12 Pages

23 November 2023

Despite the motivation of oncology patients to take part in clinical trials, only a minority of them are enrolled in clinical trials. Implementation of new practical procedures can become a barrier that withholds patients from participating in clinic...

  • Article
  • Open Access
11 Citations
2,288 Views
19 Pages

Patient-Reported Outcome Measures of Flapless Corticotomy with Low-Level Laser Therapy in En Masse Retraction of Upper Anterior Teeth: A Three-Arm Randomized Controlled Trial

  • Mudar M. Mousa,
  • Mohammad Y. Hajeer,
  • Ahmad S. Burhan,
  • Khaldoun M. A. Darwich,
  • Wael H. Almahdi,
  • Ossama Aljabban,
  • Mohammed A. Awawdeh and
  • Imad Addin Almasri

22 November 2023

(1) Background: This study aimed to compare patient-reported outcome measures when accelerating en masse retraction between the piezocision procedure and the subsequent application of low-level laser therapy (FC+LLLT), with the piezocision alone (FC)...

  • Article
  • Open Access
3 Citations
3,150 Views
13 Pages

Characteristics of Tuberculous Meningitis in HIV-Positive Patients from Northeast Romania

  • Isabela Ioana Loghin,
  • Andrei Vâță,
  • Egidia Gabriela Miftode,
  • Mihaela Cobaschi,
  • Șerban Alin Rusu,
  • George Silvaș,
  • Otilia Elena Frăsinariu and
  • Carmen Mihaela Dorobăț

21 November 2023

Background and objectives: One of the most severe forms of extrapulmonary tuberculosis (EPTB) is tuberculous meningitis (TBM), which is linked to significant morbidity and high mortality. It is well recognized that human immunodeficiency virus (HIV)-...

  • Article
  • Open Access
51 Citations
9,040 Views
28 Pages

Evaluating the Efficacy of ChatGPT in Navigating the Spanish Medical Residency Entrance Examination (MIR): Promising Horizons for AI in Clinical Medicine

  • Francisco Guillen-Grima,
  • Sara Guillen-Aguinaga,
  • Laura Guillen-Aguinaga,
  • Rosa Alas-Brun,
  • Luc Onambele,
  • Wilfrido Ortega,
  • Rocio Montejo,
  • Enrique Aguinaga-Ontoso,
  • Paul Barach and
  • Ines Aguinaga-Ontoso

20 November 2023

The rapid progress in artificial intelligence, machine learning, and natural language processing has led to increasingly sophisticated large language models (LLMs) for use in healthcare. This study assesses the performance of two LLMs, the GPT-3.5 an...

  • Article
  • Open Access
2,519 Views
11 Pages

Parental Home Safety Practices for Domestic Accident Prevention: How Prepared Were Parents for COVID-19 Confinement? A Cross-Sectional Study

  • Eirini Papachristou,
  • Savas Deftereos,
  • Maria Asimakidou,
  • Konstantina Bekiaridou,
  • Soultana Foutzitzi,
  • Soteria Defteraiou,
  • Panagoula Oikonomou,
  • Ioannis Gogoulis,
  • Christina Nikolaou and
  • Katerina Kambouri
  • + 4 authors

15 November 2023

(1) Background: Children are susceptible to home injuries. How prepared parents were to protect their children from accidents before and during the COVID-19 quarantine is uncertain. (2) Methods: We conducted a community-based, cross-sectional study i...

  • Review
  • Open Access
10 Citations
5,526 Views
22 Pages

15 November 2023

Neuroimaging can provide significant benefits in evaluating patients with movement disorders associated with drugs. This literature review describes neuroimaging techniques performed to distinguish Parkinson’s disease from drug-induced parkinso...

  • Systematic Review
  • Open Access
19 Citations
7,789 Views
14 Pages

Breast Cancer and Fertility Preservation in Young Female Patients: A Systematic Review of the Literature

  • Ioannis Boutas,
  • Adamantia Kontogeorgi,
  • Nektarios Koufopoulos,
  • Dionysios T. Dimas,
  • Kyparissia Sitara,
  • Sophia N. Kalantaridou and
  • Constantine Dimitrakakis

13 November 2023

Introduction: Breast cancer affects almost 1.5 million women worldwide below the age of 45 years each year. Many of these women will be advised to undergo adjuvant chemotherapy to minimize the risk of death or recurrence of the tumor. For these patie...

  • Article
  • Open Access
3 Citations
2,647 Views
13 Pages

13 November 2023

The prevalence of diabetes mellitus (DM) is increasing rapidly worldwide. Without proper management, DM can have serious complications. We aimed to investigate the association between protection motivation theory (PMT) constructs, self-care behaviors...

  • Case Report
  • Open Access
3 Citations
4,522 Views
7 Pages

A Case Report: Idiopathic or Drug-Induced Autoimmune Hepatitis—Can We Draw a Line?

  • Dorotea Božić,
  • Ante Tonkić,
  • Katarina Vukojevic and
  • Maja Radman

13 November 2023

Idiosyncratic drug-induced liver injury (DILI) is an unpredictable reaction of individuals exposed to a certain drug, and drug-induced autoimmune hepatitis (DIAIH) presents a DILI phenotype that mimics idiopathic autoimmune hepatitis (AIH) when consi...

  • Article
  • Open Access
3 Citations
3,438 Views
10 Pages

Clinical Outcomes of COVID-19 Infection among Patients with Chronic Obstructive Pulmonary Disease: Findings from the Philippine CORONA Study

  • Roland Dominic G. Jamora,
  • Albert B. Albay,
  • Mary Bianca Doreen F. Ditching,
  • Marie Charmaine C. Sy,
  • Emilio Q. Villanueva,
  • Adrian I. Espiritu and
  • Veeda Michelle M. Anlacan

10 November 2023

Background: The global pandemic caused by the coronavirus disease 2019 (COVID-19) resulted in many deaths from fulminant respiratory failure. Chronic obstructive pulmonary disease (COPD) is the leading cause of morbidity and mortality worldwide. Ther...

  • Article
  • Open Access
11 Citations
3,673 Views
14 Pages

Imaging Features of Alveolar Soft Part Sarcoma: Single Institution Experience and Literature Review

  • Paolo Spinnato,
  • Nicolas Papalexis,
  • Marco Colangeli,
  • Marco Miceli,
  • Amandine Crombé,
  • Anna Parmeggiani,
  • Emanuela Palmerini,
  • Alberto Righi and
  • Giuseppe Bianchi

1 November 2023

Alveolar soft part sarcoma (ASPS) is an extremely rare and aggressive soft-tissue sarcoma (STS) subtype with poor prognosis and limited response to radiation therapy and chemotherapy. Prompt recognition and referral to sarcoma centers for appropriate...

  • Review
  • Open Access
32 Citations
5,629 Views
9 Pages

Gender-Related Issues in the Management of Low-Back Pain: A Current Concepts Review

  • Davide Bizzoca,
  • Giuseppe Solarino,
  • Alessandro Pulcrano,
  • Giovanni Brunetti,
  • Anna Maria Moretti,
  • Lorenzo Moretti,
  • Andrea Piazzolla and
  • Biagio Moretti

30 October 2023

Background: Low back pain (LBP) is an emerging disease. This review aims to investigate the role of gender-related factors in the diagnosis, clinical, and surgical management of LBP. Methods: From January 2002 to March 2023, EMBASE, SCOPUS, OVID-MEDL...

  • Article
  • Open Access
2,107 Views
8 Pages

Cross-Cultural Adaptation, Reliability, and Validity of the Polish Version of the Neck Outcome Score

  • Nicola Dyrek,
  • Łukasz Pulik,
  • Aleksandra Piwowarczyk,
  • Wiktoria Skała,
  • Nina Grabowska-Mycko and
  • Paweł Łęgosz

30 October 2023

This study aimed to translate and psychometrically validate the Neck Outcome Score (NOOS) in the Polish population according to the recommendations of the American Academy of Orthopedic Surgeons Participants completed online version of the NOOS, Neck...

  • Article
  • Open Access
1 Citations
6,787 Views
17 Pages

Predicting Chronic Hyperplastic Candidiasis Retro-Angular Mucosa Using Machine Learning

  • Omid Moztarzadeh,
  • Jan Liska,
  • Veronika Liskova,
  • Alena Skalova,
  • Ondrej Topolcan,
  • Alireza Jamshidi and
  • Lukas Hauer

28 October 2023

Chronic hyperplastic candidiasis (CHC) presents a distinctive and relatively rare form of oral candidal infection characterized by the presence of white or white–red patches on the oral mucosa. Often mistaken for leukoplakia or erythroleukoplak...

  • Editorial
  • Open Access
4 Citations
5,266 Views
4 Pages

Use and Abuse of Digital Devices: Influencing Factors of Child and Adolescent Neuropsychology

  • Carola Costanza,
  • Luigi Vetri,
  • Marco Carotenuto and
  • Michele Roccella

27 October 2023

The impact of technology on human life is significant, touching various aspects such as communication, economy, education, medicine, industry, and even ecosystems [...]

  • Article
  • Open Access
2 Citations
2,189 Views
12 Pages

A Scientometric Evaluation of COVID-19 and Male Reproductive Research

  • Manesh Kumar Panner Selvam,
  • Anika Kapoor,
  • Saradha Baskaran,
  • Ajaya Kumar Moharana and
  • Suresh C. Sikka

26 October 2023

The COVID-19 pandemic due to the SARS-CoV-2 coronavirus showed acute and prolonged effects on human health. In addition, over the past four years, there has been a tremendous surge in COVID-19-related scientific publications, as shown by bibliometric...

  • Case Report
  • Open Access
2 Citations
4,129 Views
6 Pages

25 October 2023

Cardiovascular diseases (CVDs) are the leading cause of death globally. Morbidity and disability related to non-fatal events are increasing exponentially. There are several symptoms that may arise after invasive therapeutic approaches such as coronar...

  • Article
  • Open Access
8 Citations
2,780 Views
10 Pages

Improvement in Left and Right Ventricular Function after Introduction of SGLT2 Inhibitors in Heart Failure Outpatients with Reduced Ejection Fraction

  • Gianmarco Alcidi,
  • Rosanna Pugliese,
  • Sara Ioannoni,
  • Matteo Romano,
  • Gianpaolo Palmieri,
  • Erika Tabella,
  • Michele Correale,
  • Matteo Di Biase,
  • Natale Daniele Brunetti and
  • Massimo Iacoviello

25 October 2023

Background: Type 2 sodium-glucose cotransporter inhibitors (SGLT2i) are among the main therapeutic options for patients with chronic heart failure with reduced ejection fraction (HFrEF). The aim of this study was to evaluate the effects of SGLT2i on...

  • Article
  • Open Access
5 Citations
4,222 Views
17 Pages

Infection Risk, Mortality, and Hypogammaglobulinemia Prevalence and Associated Factors in Adults Treated with Rituximab: A Tertiary Care Center Experience

  • Moustafa S. Alhamadh,
  • Thamer S. Alhowaish,
  • Alaa Mathkour,
  • Bayan Altamimi,
  • Shahd Alheijani and
  • Abdulrahman Alrashid

25 October 2023

Background: Rituximab is a human monoclonal antibody directed against the B-cell transmembrane protein CD20. Although well-tolerated, given its mechanism of action, rituximab can induce a state of severe immunosuppression, increasing the risk of oppo...

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Clin. Pract. - ISSN 2039-7283