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Journal of Xenobiotics, Volume 15, Issue 2

April 2025 - 27 articles

Cover Story: We here present an important study that highlights the prevalence of environmental metal exposure among pregnant women, a critical issue that can have significant implications for maternal and fetal health. Understanding this exposure allows individuals to recognize potential health risks for both mothers and their babies. This information is valuable for anyone interested in maternal and child health, as it raises awareness about the necessity of being mindful of environmental factors during pregnancy. View this paper
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Articles (27)

  • Article
  • Open Access
923 Views
23 Pages

Genetic Interactions of Phase II Xenobiotic-Metabolizing Enzymes GSTO1 and GCLC in Relation to Alcohol Abuse and Psoriasis Risk

  • Roman Saranyuk,
  • Olga Bushueva,
  • Ekaterina Efanova,
  • Maria Solodilova,
  • Mikhail Churnosov and
  • Alexey Polonikov

20 April 2025

The present pilot study aimed to investigate whether common single nucleotide polymorphisms (SNPs) in the gene encoding glutathione S-transferase omega 1 (GSTO1), both individually and in combination with variants of the catalytic subunit of the glut...

  • Review
  • Open Access
37 Citations
9,913 Views
38 Pages

18 April 2025

Heavy metal contamination in marine ecosystems poses a critical environmental challenge, with significant implications for biodiversity, trophic dynamics, and human health. Marine fish are key bioindicators of heavy metal pollution because of their r...

  • Article
  • Open Access
15 Citations
2,261 Views
19 Pages

18 April 2025

Fluorinated pyrethroids, such as cyfluthrin and cyhalothrin, are more effective insecticides due to their enhanced stability and lipophilicity. However, they pose greater risks to non-target organisms. Their persistence in the environment and accumul...

  • Article
  • Open Access
2 Citations
1,215 Views
12 Pages

16 April 2025

Background: Heavy metal interactions within aquatic ecosystems significantly affect fish physiology. This study evaluated the protective role of selenium against cadmium-induced hematological, biochemical, and electrophoretic alterations in goldfish....

  • Article
  • Open Access
1,613 Views
19 Pages

15 April 2025

We investigated the relationship between antibiotic-resistance genes and the antimicrobial agents, triclosan (TCS) and propylparaben (PPB). The greywater microbiome was repeatedly exposed to triclosan and propylparaben and the effect was analyzed usi...

  • Review
  • Open Access
3 Citations
5,321 Views
35 Pages

Stability Dynamics of Plant-Based Extracellular Vesicles Drug Delivery

  • Satyavati Rawat,
  • Sanchit Arora,
  • Madhukiran R. Dhondale,
  • Mansi Khadilkar,
  • Sanjeev Kumar and
  • Ashish Kumar Agrawal

13 April 2025

Plant-based extracellular vesicles (PBEVs) have been recognized for their wide range of applications in drug delivery however, the extent of their medicinal applicability depends on how well they are preserved and stored. Assessing their physicochemi...

  • Review
  • Open Access
8 Citations
5,425 Views
18 Pages

Manganese (Mn) is an essential trace element and a cofactor for several key enzymes, such as mitochondrial superoxide dismutase. Consequently, it plays an important defense role against reactive oxygen species. Despite this, Mn chronic overexposure c...

  • Article
  • Open Access
2 Citations
4,806 Views
13 Pages

While cigarette smoking has declined, e-cigarette use among young adults has increased in the USA. This cross-sectional study compared complete blood counts, C-reactive protein, and select blood metals (lead, cadmium, mercury, selenium, manganese) am...

  • Article
  • Open Access
1 Citations
3,115 Views
18 Pages

A Novel Protocol for Culturing Polarized Proximal Tubular Epithelial Cells from Kidney Biopsies: Enhancing Platforms for Drug Excretion and Nephrotoxicity Studies

  • Tadej Petreski,
  • Lidija Gradišnik,
  • Luka Varda,
  • Polona Kovačič,
  • Jurij Dolenšek,
  • Andraž Stožer,
  • Sebastjan Bevc and
  • Uroš Maver

The kidneys are integral to homeostasis but are susceptible to nephrotoxic compounds. Proximal tubular epithelial cells (PTECs) mediate drug metabolism and transport and are widely used in preclinical studies. However, commercial PTECs are limited in...

  • Review
  • Open Access
5 Citations
6,606 Views
29 Pages

31 March 2025

Cardiovascular diseases (CVDs) represent a leading cause of premature mortality and disability worldwide, with their incidence expected to rise, potentially reaching 24 million deaths per year by 2030. These multifactorial diseases, including hyperte...

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J. Xenobiot. - ISSN 2039-4713