Table of Contents
Pharmaceutics, Volume 11, Issue 2 (February 2019)
- Issues are regarded as officially published after their release is announced to the table of contents alert mailing list.
- You may sign up for e-mail alerts to receive table of contents of newly released issues.
- PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.
Cover Story (view full-size image) Dr. Jong Oh Kim and his colleagues created transferrin-conjugated polymeric nanoparticles as [...] Read more. Dr. Jong Oh Kim and his colleagues created transferrin-conjugated polymeric nanoparticles as doxorubicin carriers to achieve maximum therapeutic efficacy of a chemotherapeutic drug, doxorubicin, in a resistant breast cancer cell line. After an in vitro cellular study, drug resistance was shown to be overcome by an accumulation of doxorubicin in the nuclear region of the cancer cell. In addition, the study showed that doxorubicin-loaded polymeric nanoparticles successfully accumulated with transferrin targeting ligands in xenograft mouse models bearing the doxorubicin-resistant cell line MDA-MB-231(R) with minimum toxicity in healthy organs. View this paper