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Viruses, Volume 5, Issue 6

June 2013 - 12 articles

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Review

36 Citations

10,020 Views

19 Pages

Regulation of Human Cytomegalovirus Transcription in Latency: Beyond the Major Immediate-Early Promoter

Matthew Reeves and
John Sinclair

Viruses2013, 5(6), 1395-1413;https://doi.org/10.3390/v5061395

3 June 2013

Lytic infection of differentiated cell types with human cytomegalovirus (HCMV) results in the temporal expression of between 170–200 open reading frames (ORFs). A number of studies have demonstrated the temporal regulation of these ORFs and that this...

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Review

38 Citations

12,550 Views

21 Pages

Current Understanding of the Role of the Brd4 Protein in the Papillomavirus Lifecycle

Alison A. McBride and
Moon Kyoo Jang

Viruses2013, 5(6), 1374-1394;https://doi.org/10.3390/v5061374

30 May 2013

The Brd4 protein is an epigenetic reader that is central to regulation of cellular transcription and mitotic bookmarking. The transcription and replication proteins of many viruses interact with Brd4. We describe the multiple roles of Brd4 in the pa...

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Viruses - ISSN 1999-4915

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