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Article

Biofilm Formation on Dental Implant Biomaterials by Staphylococcus aureus Strains Isolated from Patients with Cystic Fibrosis

1
Department of Medical Biology, Medical University of Warsaw, Litewska 14/16, 00-575 Warsaw, Poland
2
Department of Microbiology, National Tuberculosis and Lung Diseases Research Institute, Płocka 26, 01-138 Warsaw, Poland
3
The Chair and Department of Oral Surgery, Medical University of Lublin, Karmelicka 7, 20-081 Lublin, Poland
4
Department of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland
5
Department of Pharmaceutical Microbiology, Centre for Preclinical Research and Technology, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1B, 02-097 Warsaw, Poland
*
Author to whom correspondence should be addressed.
Academic Editor: Lucio Montanaro
Materials 2021, 14(8), 2030; https://doi.org/10.3390/ma14082030
Received: 6 March 2021 / Revised: 14 April 2021 / Accepted: 15 April 2021 / Published: 17 April 2021
(This article belongs to the Special Issue Properties of Dental Restorative Materials)
Implants made of ceramic and metallic elements, which are used in dentistry, may either promote or hinder the colonization and adhesion of bacteria to the surface of the biomaterial to varying degrees. The increased interest in the use of dental implants, especially in patients with chronic systemic diseases such as cystic fibrosis (CF), is caused by an increase in disease complications. In this study, we evaluated the differences in the in vitro biofilm formation on the surface of biomaterials commonly used in dentistry (Ti-6Al-4V, cobalt-chromium alloy (CoCr), and zirconia) by Staphylococcus aureus isolated from patients with CF. We demonstrated that S. aureus adherence and growth depends on the type of material used and its surface topography. Weaker bacterial biofilm formation was observed on zirconia surfaces compared to titanium and cobalt-chromium alloy surfaces. Moreover, scanning electron microscopy showed clear differences in bacterial aggregation, depending on the type of biomaterial used. Over the past several decades, S. aureus strains have developed several mechanisms of resistance, especially in patients on chronic antibiotic treatment such as CF. Therefore, the selection of an appropriate implant biomaterial with limited microorganism adhesion characteristics can affect the occurrence and progression of oral cavity infections, particularly in patients with chronic systemic diseases. View Full-Text
Keywords: biomaterials; Ti-6Al-4V; CoCr alloy; zirconia; biofilm; Staphylococcus aureus; cystic fibrosis; SEM; AFM biomaterials; Ti-6Al-4V; CoCr alloy; zirconia; biofilm; Staphylococcus aureus; cystic fibrosis; SEM; AFM
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MDPI and ACS Style

Minkiewicz-Zochniak, A.; Jarzynka, S.; Iwańska, A.; Strom, K.; Iwańczyk, B.; Bartel, M.; Mazur, M.; Pietruczuk-Padzik, A.; Konieczna, M.; Augustynowicz-Kopeć, E.; Olędzka, G. Biofilm Formation on Dental Implant Biomaterials by Staphylococcus aureus Strains Isolated from Patients with Cystic Fibrosis. Materials 2021, 14, 2030. https://doi.org/10.3390/ma14082030

AMA Style

Minkiewicz-Zochniak A, Jarzynka S, Iwańska A, Strom K, Iwańczyk B, Bartel M, Mazur M, Pietruczuk-Padzik A, Konieczna M, Augustynowicz-Kopeć E, Olędzka G. Biofilm Formation on Dental Implant Biomaterials by Staphylococcus aureus Strains Isolated from Patients with Cystic Fibrosis. Materials. 2021; 14(8):2030. https://doi.org/10.3390/ma14082030

Chicago/Turabian Style

Minkiewicz-Zochniak, Anna, Sylwia Jarzynka, Agnieszka Iwańska, Kamila Strom, Bartłomiej Iwańczyk, Marta Bartel, Maciej Mazur, Anna Pietruczuk-Padzik, Małgorzata Konieczna, Ewa Augustynowicz-Kopeć, and Gabriela Olędzka. 2021. "Biofilm Formation on Dental Implant Biomaterials by Staphylococcus aureus Strains Isolated from Patients with Cystic Fibrosis" Materials 14, no. 8: 2030. https://doi.org/10.3390/ma14082030

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