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Pathophysiology, Volume 31, Issue 4

December 2024 - 15 articles

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Articles (15)

  • Review
  • Open Access
6 Citations
2,793 Views
12 Pages

Flavonoid-Mediated Suppression of Tumor Angiogenesis: Roles of Ang-Tie/PI3K/AKT

  • Shallu Saini,
  • Hardeep Singh Tuli,
  • Reena V. Saini,
  • Adesh K. Saini,
  • Katrin Sak,
  • Damandeep Kaur,
  • Moyad Shahwan,
  • Ritu Chauhan and
  • Abhishek Chauhan

Angiogenesis is a process involved in the formation of new blood capillaries from pre-existing ones. It is regulated by several anti-angiogenic molecules involved in tumor growth and metastasis. The endothelial angiopoietin Ang-Tie/PI3K/AKT growth re...

  • Review
  • Open Access
1 Citations
6,799 Views
13 Pages

Pathophysiology and Prevention of Manual-Ventilation-Induced Lung Injury (MVILI)

  • Luke A. White,
  • Steven A. Conrad and
  • Jonathan Steven Alexander

Manual ventilation, most commonly with a bag-valve mask, is a form of short-term ventilation used during resuscitative efforts in emergent and out-of-hospital scenarios. However, compared to mechanical ventilation, manual ventilation is an operator-d...

  • Article
  • Open Access
3 Citations
3,076 Views
24 Pages

Multiple Benefits of Empagliflozin in PCOS: Evidence from a Preclinical Rat Model

  • Dejana Rakic,
  • Vladimir Jakovljevic,
  • Vladimir Zivkovic,
  • Jovana Jakovljevic Uzelac,
  • Nikola Jovic,
  • Maja Muric,
  • Bozidar Pindovic,
  • Aleksandra Dimitrijevic,
  • Petar Arsenijevic and
  • Jovan Rakic
  • + 3 authors

Polycystic ovary syndrome (PCOS) is the most common complex endocrinological condition of women that is associated with infertility and metabolic disorders during the reproductive period. Recently, a great deal of research has focused on the etiopath...

  • Review
  • Open Access
8 Citations
3,543 Views
14 Pages

Pathways to Alzheimer’s Disease: The Intersecting Roles of Clusterin and Apolipoprotein E in Amyloid-β Regulation and Neuronal Health

  • Alexandru Laslo,
  • Laura Laslo,
  • Eliza-Mihaela Arbănași,
  • Alexandru-Andrei Ujlaki-Nagi,
  • Laura Chinezu,
  • Adrian Dumitru Ivănescu,
  • Emil-Marian Arbănași,
  • Roxana Octavia Cărare,
  • Bogdan Andrei Cordoș and
  • Ioana Adriana Popa
  • + 1 author

One of the hallmarks of Alzheimer’s disease (AD) is the deposition of amyloid-β (Aβ) within the extracellular spaces of the brain as plaques and along the blood vessels in the brain, a condition also known as cerebral amyloid angiopat...

  • Article
  • Open Access
1,697 Views
15 Pages

Early Radiation-Induced Changes in Lung Tissue and Intercellular Junctions: Implications for Tissue Repair and Fibrosis

  • Ekaterina S. Karetnikova,
  • Alexandra A. Livanova,
  • Arina A. Fedorova and
  • Alexander G. Markov

Early changes in lung tissue following ionizing radiation (IR) initiate processes that may lead to either regeneration or fibrosis. Intercellular junction proteins play a crucial role in the organization and function of epithelial tissues, both under...

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Pathophysiology - ISSN 1873-149X