2013 August - 18 articles
In this issue of Current Oncology, Qin and colleagues from the Sun Yat-sen University Cancer Centre in Guangzhou, China, report their experience using toremifene as adjuvant treatment for 396 premenopausal women with early endocrine-responsive breast...
Human papillomavirus (HPV) was first detected in head-and-neck cancers in the 1980s1.[...]
Background: Given the use of tamoxifen as standard treatment for hormone receptor–positive breast cancer, the use of toremifene as an adjuvant endocrine therapy has not been widely examined. The present retrospective study compared the efficacy and s...
Background: Node-negative breast cancers from 2 cm to 5 cm in size are classified as stage ii, and smaller cancers, as stage i. We sought to determine if the prognosis of women with a breast cancer exactly 2 cm in size more closely resembles that of...
Background: Sexually transmitted infection with the human papillomavirus (HPV) is responsible for a significant burden of human cancers involving the cervix, anogenital tract, and oropharynx. Studies in the United States and Europe have demonstrated...
This paper summarizes the practical impact of the College of American Pathologists, the International Association for the Study of Lung Cancer, and the Association for Molecular Pathology lung cancer biomarkers guidelines on the lung cancer approach...
Colorectal cancer is the second leading cause of cancer death and the third most commonly diagnosed cancer in Canada, with an estimated 9200 deaths and 23,300 new cases in 2012. [...]
Patients with lung cancer have a symptom burden— including fatigue, anorexia, and weight loss—that is among the highest for all types of cancer1.[...]
Increased insulin-like growth factor (IGF) signalling has been observed in breast cancer, including endocrine-responsive cancers, and has been linked to disease progression and recurrence. In particular, IGF-1 has the ability to induce and promote ly...
Background: In Canada, many diverse models of integrative oncology care have emerged in response to the growing number of cancer patients who combine complementary therapies with their conventional medical treatments. The increasing interest in integ...
Background: The prognosis of patients with brain metastases from non-small-cell lung cancer (NSCLC) is poor. However, some reports suggest that patients with brain metastases at the time of initial diagnosis have a more favourable survival than do pa...
Background: This observational study set out to evaluate the effectiveness of conscious sedation anesthesia for pain control during high-dose-rate (HDR) brachytherapy using a ring-and-tandem applicator system for patients with cervical cancer. Method...
Extramammary Paget disease (empd) is a rare, slow-growing neoplasm, considered to be an adenocarcinoma of the apocrine glands. In men, the penoscrotal region is the most commonly affected area. The disease can present as carcinoma in situ or as invas...
In this systematic review, we sought to evaluate the effect of physical activity or nutrition interventions (or both) in adults with advanced non-small-cell lung cancer (NSCLC). Methods: A systematic search for relevant clinical trials was conducted...
Background: Cancer can be a devastating diagnosis. In particular, malignancy and its indicated treatments have profoundly negative effects on the fertility of young cancer patients. Oncofertility has emerged as a new interdisciplinary field to addres...
To evaluate an Aloe vera lotion for prevention of radiation-induced dermatitis, all patients with a prescription of radiotherapy to a minimum dose of 40 Gy were eligible provided that their treatment area could be divided into two symmetrical halves....
Mastocytosis is an uncommon disorder defined by increased and abnormal mast cells in one or more tissues. Cutaneous mastocytosis (CM) is limited to the skin, with varying degrees of rash, pruritus, and disfigurement. Systemic mastocytosis (SM) typica...
Parotid metastases from non–head-and-neck cancers are rare and may represent a diagnostic and therapeutic challenge. A late metastasis to the parotid gland from a seminoma is an unusual manifestation of disease. A 45-year-old man with a history of te...
