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Isolation of C11 Cyclopentenones from Two Didemnid Species, Lissoclinum sp. and Diplosoma sp.

1
Department of Chemistry, Biology and Marine Science, University of the Ryukyus, 1 Senbaru, Nishihara, Okinawa 903-0213, Japan
2
Okinawa Industrial Technology Center, 12-2 Suzaki, Uruma, Okinawa 904-2234, Japan
3
Faculty of Education, University of the Ryukyus, 1 Senbaru, Nishihara, Okinawa 903-0213, Japan
4
Department of Bioresources Engineering, Okinawa National College of Technology, 905 Henoko, Nago, Okinawa 905-2192, Japan
5
Department of Chemistry, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama, Kanagawa 223-8522, Japan
*
Author to whom correspondence should be addressed.
Mar. Drugs 2009, 7(4), 816-832; https://doi.org/10.3390/md7040816
Received: 19 November 2009 / Revised: 14 December 2009 / Accepted: 16 December 2009 / Published: 17 December 2009
A series of new C11 cyclopentenones 1-7 was isolated, together with four known metabolites 9/10, 12 and 13, from the extract of the didemnid ascidian Lissoclinum sp. The other didemnid ascidian Diplosoma sp. contained didemnenones 1, 2 and 5, and five known metabolites 8-12. The structures of 1-7 were elucidated by spectroscopic analyses. Cytotoxicity of the isolated compounds was evaluated against three human cancer cell lines (HCT116, A431 and A549). View Full-Text
Keywords: Lissoclinum; Diplosoma; cyclopentenone; didemnenone; cytotoxicity Lissoclinum; Diplosoma; cyclopentenone; didemnenone; cytotoxicity
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MDPI and ACS Style

Ogi, T.; Margiastuti, P.; Teruya, T.; Taira, J.; Suenaga, K.; Ueda, K. Isolation of C11 Cyclopentenones from Two Didemnid Species, Lissoclinum sp. and Diplosoma sp. Mar. Drugs 2009, 7, 816-832. https://doi.org/10.3390/md7040816

AMA Style

Ogi T, Margiastuti P, Teruya T, Taira J, Suenaga K, Ueda K. Isolation of C11 Cyclopentenones from Two Didemnid Species, Lissoclinum sp. and Diplosoma sp. Marine Drugs. 2009; 7(4):816-832. https://doi.org/10.3390/md7040816

Chicago/Turabian Style

Ogi, Takayuki; Margiastuti, Palupi; Teruya, Toshiaki; Taira, Junsei; Suenaga, Kiyotake; Ueda, Katsuhiro. 2009. "Isolation of C11 Cyclopentenones from Two Didemnid Species, Lissoclinum sp. and Diplosoma sp." Mar. Drugs 7, no. 4: 816-832. https://doi.org/10.3390/md7040816

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