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Medicina, Volume 61, Issue 5

May 2025 - 173 articles

Cover Story: Despite the widespread success of total knee arthroplasty (TKA), 10–20% of patients are dissatisfied, often due to persistent pain, instability, or unnatural knee motion. Advancements in surgical techniques, alignment philosophies, and implant designs have been introduced to increase the satisfaction rate. Medial stabilized TKA have been developed to better replicate native knee kinematics and improve clinical and functional outcomes. This review provides an overview on the current clinical evidence on two types of medial stabilized TKA implants (medial congruent and medial pivot), focusing on different alignment and soft tissue balancing techniques. View this paper
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Articles (173)

  • Article
  • Open Access
1 Citations
873 Views
11 Pages

Background and Objectives: To examine individual-level sex differences in traditional and non-traditional risk factors and their potential effects on the severity of coronary artery disease (CAD). Materials and Methods: A cross-sectional analysis was...

  • Article
  • Open Access
1,644 Views
16 Pages

Integrating Brain-Computer Interface Systems into Occupational Therapy for Enhanced Independence of Stroke Patients: An Observational Study

  • Erika Endzelytė,
  • Daiva Petruševičienė,
  • Raimondas Kubilius,
  • Sigitas Mingaila,
  • Jolita Rapolienė and
  • Inesa Rimdeikienė

Background and Objectives: Brain-computer interface (BCI) technology is revolutionizing stroke rehabilitation by offering innovative neuroengineering solutions to address neurological deficits. By bypassing peripheral nerves and muscles, BCIs enable...

  • Article
  • Open Access
1,079 Views
13 Pages

Quality of Life, Caregiver Burden, and Symptoms of Depression and Anxiety in Parents of Children with Spinal Muscular Atrophy: A Comparison with Healthy Controls

  • Zehra Koyuncu,
  • Seda Sönmez Kurukaya,
  • Fitnat Uluğ,
  • Tuğçe Damla Dilek,
  • Yılmaz Zindar,
  • Büşra Arslan,
  • Berkay Tayşi,
  • Elif Anaç,
  • Mustafa Balkanas and
  • Sena Kesik
  • + 4 authors

Background: Spinal muscular atrophy (SMA) is a disease that leads to muscle weakness and significantly affects the lives of both patients and caregivers. This study aims to compare quality of life, caregiver burden, symptoms of depression and anxiety...

  • Article
  • Open Access
852 Views
16 Pages

Biomarker Patterns and Their Association with Lung Injury in COVID-19 Patients

  • Alexandru Constantin Sîrbu,
  • Anca Daniela Farcaș,
  • Ioana Corina Bocsan,
  • Maria Adriana Neag,
  • Ștefan Cristian Vesa,
  • Șoimița Mihaela Suciu and
  • Anca Dana Buzoianu

Background and Objectives: The study investigates the relationship between accessible biomarkers and the extent of lung damage, assessed with computed tomography (CT) imaging, in patients hospitalized for COVID-19. Materials and Methods: This retrosp...

  • Systematic Review
  • Open Access
2,959 Views
11 Pages

Efficacy and Safety of Nitrous Oxide (N2O) Inhalation Sedation Compared to Other Sedative Agents in Dental Procedures: A Systematic Review with Meta-Analysis

  • Francesca Piccialli,
  • Marco Fiore,
  • Roberto Giurazza,
  • Fabrizio Falso,
  • Vittorio Simeon,
  • Paolo Chiodini,
  • Diana Russo and
  • Luigi Laino

Background and Objectives: Dental procedures can be distressing, particularly for patients who are anxious or uncooperative. In such cases, effective sedation not only facilitates the clinician’s work but also enhances patient comfort and accep...

  • Article
  • Open Access
1,961 Views
10 Pages

Background: This retrospective study evaluated and compared oncological outcomes in patients with localized prostate cancer treated either by laparoscopic radical prostatectomy (LRP) or by external beam radiotherapy (EBRT) combined with androgen depr...

  • Article
  • Open Access
1,112 Views
19 Pages

Aim: This study aimed to investigate the effect of Euthyroid Sick Syndrome (ESS) on non-invasive mechanical ventilation (NIV) failure and in-hospital mortality. We also examined the impact of prolonged low fT3 levels before intensive care unit (ICU)...

  • Article
  • Open Access
1 Citations
1,152 Views
11 Pages

Clinical Effectiveness, Clinical Stability, and Effects on Serum Galectin-7 Levels of Dupilumab and JAK Inhibitors in Moderate-to-Severe Atopic Dermatitis: A Real-World, Single-Center Analysis

  • Akihiro Horie,
  • Tomomitsu Miyagaki,
  • Chikako Hiranuma,
  • Mami Iijima,
  • Yoshiaki Hara,
  • Shinya Oba,
  • Mina Hashimoto,
  • Reina Omori,
  • Tatsuro Okano and
  • Takafumi Kadono

Background and Objectives: Several biologics and oral Janus kinase (JAK) inhibitors have been developed and shown in clinical trials and real-world studies to be effective and safe in moderate-to-severe atopic dermatitis (AD). In this study, we aimed...

  • Article
  • Open Access
691 Views
12 Pages

Clinical and Sociodemographic Characteristics of Patients with Peripheral Facial Paralysis in Medical Rehabilitation: A Comprehensive Description

  • María Navarro-Martínez,
  • Paula Rodríguez-Fernández,
  • Sandra Núñez-Rodríguez and
  • Jerónimo Javier González-Bernal

Background and Objectives: Peripheral facial paralysis (PFP) is a condition with diverse etiologies, requiring multidisciplinary management. This study aimed to describe the sociodemographic, clinical, and functional characteristics of patients with...

  • Review
  • Open Access
1,116 Views
12 Pages

Prostate-Specific Membrane Antigen Positron Emission Tomography (PSMA-PET) in Initial Staging of Prostate Cancer Patients: The Beginning of a New Era

  • Juan Gómez Rivas,
  • Irene de la Parra,
  • Sarelis Infante,
  • Laura Ibañez,
  • Beatriz Gutierrez Hidalgo,
  • María Nieves Cabrera,
  • Javier Puente,
  • Noelia Sanmamed,
  • Luis Enrique Ortega Polledo and
  • María Isabel Galante
  • + 1 author

Background and Objectives: Prostate cancer (PCa) is a common disease, with a significant number of patients initially diagnosed with locoregional or distant metastases. This is why it is essential to have imaging tests with sufficient sensitivity and...

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Medicina - ISSN 1648-9144