Next Article in Journal
Increased Angiogenesis and Lymphangiogenesis in the Placental Villi of Women with Chronic Venous Disease during Pregnancy
Next Article in Special Issue
Plant Cell Wall Proteins and Development
Previous Article in Journal
Female AhR Knockout Mice Develop a Minor Renal Insufficiency in an Adenine-Diet Model of Chronic Kidney Disease
Previous Article in Special Issue
Correction: Cherkaoui, M., Lollier, V., Geairon, A., Bouder, A., Larré, C., Rogniaux, H., Jamet, E., Guillon, F. and Francin-Allami, M. Cell Wall Proteome of Wheat Grain Endosperm and Outer Layers at Two Key Stages of Early Development. Int. J. Mol. Sci. 2020, 21, 239
Open AccessArticle

The Cell Wall PAC (Proline-Rich, Arabinogalactan Proteins, Conserved Cysteines) Domain-Proteins Are Conserved in the Green Lineage

1
Laboratoire de Recherche en Sciences Végétales, Université de Toulouse, CNRS, UPS, 31320 Auzeville Tolosane, France
2
Paris-Lodron-University of Salzburg, Department of Biosciences, Salzburg 5020, Austria
*
Author to whom correspondence should be addressed.
These two authors equally contributed to the work.
Int. J. Mol. Sci. 2020, 21(7), 2488; https://doi.org/10.3390/ijms21072488
Received: 17 January 2020 / Revised: 25 March 2020 / Accepted: 1 April 2020 / Published: 3 April 2020
(This article belongs to the Special Issue Plant Cell Wall Proteins and Development)
Plant cell wall proteins play major roles during plant development and in response to environmental cues. A bioinformatic search for functional domains has allowed identifying the PAC domain (Proline-rich, Arabinogalactan proteins, conserved Cysteines) in several proteins (PDPs) identified in cell wall proteomes. This domain is assumed to interact with pectic polysaccharides and O-glycans and to contribute to non-covalent molecular scaffolds facilitating the remodeling of polysaccharidic networks during rapid cell expansion. In this work, the characteristics of the PAC domain are described in detail, including six conserved Cys residues, their spacing, and the predicted secondary structures. Modeling has been performed based on the crystal structure of a Plantago lanceolata PAC domain. The presence of β-sheets is assumed to ensure the correct folding of the PAC domain as a β-barrel with loop regions. We show that PDPs are present in early divergent organisms from the green lineage and in all land plants. PAC domains are associated with other types of domains: Histidine-rich, extensin, Proline-rich, or yet uncharacterized. The earliest divergent organisms having PDPs are Bryophytes. Like the complexity of the cell walls, the number and complexity of PDPs steadily increase during the evolution of the green lineage. The association of PAC domains with other domains suggests a neo-functionalization and different types of interactions with cell wall polymers View Full-Text
Keywords: cell wall; evolution; green lineage; modeling; PAC domain; phylogeny; plant cell wall; evolution; green lineage; modeling; PAC domain; phylogeny; plant
Show Figures

Figure 1

MDPI and ACS Style

Nguyen-Kim, H.; San Clemente, H.; Laimer, J.; Lackner, P.; Gadermaier, G.; Dunand, C.; Jamet, E. The Cell Wall PAC (Proline-Rich, Arabinogalactan Proteins, Conserved Cysteines) Domain-Proteins Are Conserved in the Green Lineage. Int. J. Mol. Sci. 2020, 21, 2488.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop