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Article

Chromosomal Signatures Corroborate the Phylogenetic Relationships within Akodontini (Rodentia, Sigmodontinae)

1
Laboratório de Citogenética, Centro de Estudos Avançados da Biodiversidade, Instituto de Ciências Biológicas, Universidade Federal do Pará (UFPA), Belém, Pará, 66075-750, Brazil
2
Cambridge Resource Centre for Comparative Genomics, Department of Veterinary Medicine, University of Cambridge, Cambridge 01223, UK
3
Laboratório de Zoologia e Ecologia de Vertebrados, ICB, Universidade Federal do Pará (UFPA), Belém, Pará, 66075-110, Brazil
4
Departamento de Zoologia, Laboratório de Mastozoologia, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, 20550-170, Brazil
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Int. J. Mol. Sci. 2020, 21(7), 2415; https://doi.org/10.3390/ijms21072415
Received: 2 March 2020 / Revised: 28 March 2020 / Accepted: 28 March 2020 / Published: 31 March 2020
(This article belongs to the Section Molecular Genetics and Genomics)
Comparative chromosome-painting analysis among highly rearranged karyotypes of Sigmodontinae rodents (Rodentia, Cricetidae) detects conserved syntenic blocks, which are proposed as chromosomal signatures and can be used as phylogenetic markers. In the Akodontini tribe, the molecular topology (Cytb and/or IRBP) shows five low-supported clades (divisions: “Akodon”, “Bibimys”, “Blarinomys”, “Oxymycterus”, and “Scapteromys”) within two high-supported major clades (clade A: “Akodon”, “Bibimys”, and “Oxymycterus”; clade B: “Blarinomys” and “Scapteromys”). Here, we examine the chromosomal signatures of the Akodontini tribe by using Hylaeamys megacephalus (HME) probes to study the karyotypes of Oxymycterus amazonicus (2n = 54, FN = 64) and Blarinomys breviceps (2n = 28, FN = 50), and compare these data with those from other taxa investigated using the same set of probes. We strategically employ the chromosomal signatures to elucidate phylogenetic relationships among the Akodontini. When we follow the evolution of chromosomal signature states, we find that the cytogenetic data corroborate the current molecular relationships in clade A nodes. We discuss the distinct events that caused karyotypic variability in the Oxymycterus and Blarinomys genera. In addition, we propose that Blarinomys may constitute a species complex, and that the taxonomy should be revised to better delimit the geographical boundaries and their taxonomic status. View Full-Text
Keywords: conserved syntenic block; chromosome painting; rodents; FISH conserved syntenic block; chromosome painting; rodents; FISH
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MDPI and ACS Style

Oliveira da Silva, W.; Malcher, S.M.; Pereira, A.L.; Pieczarka, J.C.; Ferguson-Smith, M.A.; O’Brien, P.C.M.; Mendes-Oliveira, A.C.; Geise, L.; Nagamachi, C.Y. Chromosomal Signatures Corroborate the Phylogenetic Relationships within Akodontini (Rodentia, Sigmodontinae). Int. J. Mol. Sci. 2020, 21, 2415. https://doi.org/10.3390/ijms21072415

AMA Style

Oliveira da Silva W, Malcher SM, Pereira AL, Pieczarka JC, Ferguson-Smith MA, O’Brien PCM, Mendes-Oliveira AC, Geise L, Nagamachi CY. Chromosomal Signatures Corroborate the Phylogenetic Relationships within Akodontini (Rodentia, Sigmodontinae). International Journal of Molecular Sciences. 2020; 21(7):2415. https://doi.org/10.3390/ijms21072415

Chicago/Turabian Style

Oliveira da Silva, Willam, Stella M. Malcher, Adenilson L. Pereira, Julio C. Pieczarka, Malcolm A. Ferguson-Smith, Patricia C.M. O’Brien, Ana C. Mendes-Oliveira, Lena Geise, and Cleusa Y. Nagamachi 2020. "Chromosomal Signatures Corroborate the Phylogenetic Relationships within Akodontini (Rodentia, Sigmodontinae)" International Journal of Molecular Sciences 21, no. 7: 2415. https://doi.org/10.3390/ijms21072415

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