Functional and Antiseptic Biomedical Surfaces and Interfaces

Topic Information

Dear Colleagues,

The use of materials for infection prevention and control plays a critical role in a world with a growing and closely interacting population. Pathogenic microorganisms may be rapidly transferred by direct contact or inhalation, and incautious use of antibiotics and antimicrobials is increasing the number of resistant species. Given these challenges, there is an urgent requirement to sense, actuate, and enable reactions on surfaces and interfaces. Examples here include nano- and micropatterned surfaces, adsorption films, and active combinations of chemical and microstructural compositions. Mechanisms of interest include molecular self-assembly, concentration gradients, electric fields, vibration, electromagnetism, and photoactive stimulation. These may activate beneficial effects at interfaces and surfaces to ensure they do not become sites for pathogen transmission. Ideally, these mechanisms will allow reactive and adaptive property changes to suit changes in circumstances. We invite original research articles and reviews covering novel materials; surface engineering techniques; nano- and micropatterns; surface and molecular interactions with cells and microorganisms; self-assembly; and applications in medical devices, implants, wound healing, infection control, industrial surfaces, and the control of the spread of infection in buildings with large numbers of people. A paradigm shift from current technologies with a focus on novel technologies such as surficial nano-robotics is strongly encouraged.

Prof. Dr. Annett Dorner-Reisel
Prof. Dr. Aneta Zima
Dr. Nick Tucker
Prof. Dr. Tao Wang
Topic Editors

Keywords

Participating Journals

Journal Name	Impact Factor	CiteScore	Launched Year	First Decision (median)	APC
Applied Nano applnano	-	5.9	2020	18.6 Days	CHF 1000
Bioengineering bioengineering	4.4	7.5	2014	16.9 Days	CHF 2700
Coatings coatings	3.4	6.1	2011	12.3 Days	CHF 2600
Journal of Functional Biomaterials jfb	5.9	9.7	2010	15.1 Days	CHF 2700
Materials materials	3.7	7.0	2008	14.4 Days	CHF 2600
Surfaces surfaces	2.7	4.2	2018	18.2 Days	CHF 1600

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All Applied Nano Bioengineering Coatings JFB Materials Surfaces

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Open AccessReview

Bacterial Biofilm and Titanium Implants: Mechanisms, Clinical Problems, and Surface Modification Strategies

by Julia Lisoń-Kubica

Materials 2026, 19(13), 2919; https://doi.org/10.3390/ma19132919 - 7 Jul 2026

Viewed by 1074

Abstract

Bacterial biofilms represent a major clinical challenge, being responsible for the majority of chronic infections and significantly reducing the effectiveness of antibiotic therapy. Their formation on implant surfaces, particularly those made of titanium and its alloys, is strongly associated not only with antimicrobial [...] Read more.

Bacterial biofilms represent a major clinical challenge, being responsible for the majority of chronic infections and significantly reducing the effectiveness of antibiotic therapy. Their formation on implant surfaces, particularly those made of titanium and its alloys, is strongly associated not only with antimicrobial tolerance but also with persistent, hard-to-eradicate infections, implant loosening or failure, repeated surgical interventions, prolonged hospitalization, and increased morbidity. These complications contribute substantially to the growing problem of antimicrobial resistance and impose significant economic burdens on healthcare systems. This review discusses the mechanisms of biofilm formation, factors influencing bacterial adhesion, and the clinical implications associated with implant-related infections. Special attention is given to titanium-based biomaterials, including conventional Ti–6Al–4V and next-generation alloys such as Ti–13Nb–13Zr, highlighting their advantages and limitations in the context of biocompatibility and susceptibility to biofilm formation. Various strategies for combating biofilms are presented, including physical, chemical, and biological approaches, with emphasis on surface modification techniques. Advanced methods, particularly atomic layer deposition (ALD), are identified as promising solutions for creating uniform, antibacterial coatings, including those based on tin dioxide (SnO₂). Such modifications offer potential for reducing bacterial adhesion, improving osseointegration, and enhancing long-term implant performance. Full article

(This article belongs to the Topic Functional and Antiseptic Biomedical Surfaces and Interfaces)

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