Challenges and Opportunities in Drug Delivery Research

Abstract submission deadline

31 December 2024

Manuscript submission deadline

31 March 2025

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Topic Information

Dear Colleagues,

The topic "Challenges and Opportunities in Drug Delivery Research" encompasses innovative drug delivery and release science research with significant implications in medical fields such as cancer therapy, neurology, and cardiovascular medicine. This pioneering research aims to transform treatment methods by developing advanced drug delivery systems that improve precision, reduce side effects, and enhance patient outcomes. The scope extends to gene therapies, personalized medicine, and novel approaches addressing complex health challenges, potentially reshaping healthcare by providing tailored and effective solutions for various diseases and conditions.

Key focus areas involve a mechanistic comprehension of drug delivery systems based on biological and physicochemical principles and mathematical modeling, predictive analytics, drug delivery systems, and cellular interactions tailored for particular therapeutic objectives.

Potential topics of interest for discussion cover various drug delivery technologies, nanomedicine, different entry pathways into the human body, technology evaluations, drug delivery strategies, precise delivery and targeting at various levels and disease indications, and preclinical and clinical findings data related to drug delivery systems. Additionally, in-depth discussions could be extended to detailed explorations of the methods involved in delivering and releasing genes, vaccines, and antibodies.

Prof. Dr. Lenuta Profire
Dr. Ioana Mirela Vasincu
Topic Editors

Keywords

Participating Journals

Journal Name	Impact Factor	CiteScore	Launched Year	First Decision (median)	APC
Current Issues in Molecular Biology cimb	3.1	2.4	1999	13.5 Days	CHF 2200	Submit
Molecules molecules	4.6	6.7	1996	14.6 Days	CHF 2700	Submit
Pharmaceuticals pharmaceuticals	4.6	4.7	2004	14.6 Days	CHF 2900	Submit
Pharmaceutics pharmaceutics	5.4	6.9	2009	14.2 Days	CHF 2900	Submit
Scientia Pharmaceutica scipharm	2.5	6.4	1930	22.7 Days	CHF 1000	Submit

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Published Papers (1 paper)

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All CIMB Molecules Pharmaceuticals Pharmaceutics Sci. Pharm.

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14 pages, 12746 KiB  

Open AccessArticle

Adenosine Encapsulation and Characterization through Layer-by-Layer Assembly of Hydroxypropyl-β-Cyclodextrin and Whey Protein Isolate as Wall Materials

by Yudie Jin and Suning Zhang

Molecules 2024, 29(9), 2046; https://doi.org/10.3390/molecules29092046 - 29 Apr 2024

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Abstract

Adenosine, as a water-soluble active substance, has various pharmacological effects. This study proposes a layer-by-layer assembly method of composite wall materials, using hydroxypropyl-$\beta$-cyclodextrin as the inner wall and whey protein isolate as the outer wall, to encapsulate adenosine within the core [...] Read more.

Adenosine, as a water-soluble active substance, has various pharmacological effects. This study proposes a layer-by-layer assembly method of composite wall materials, using hydroxypropyl-$\beta$-cyclodextrin as the inner wall and whey protein isolate as the outer wall, to encapsulate adenosine within the core material, aiming to enhance adenosine microcapsules’ stability through intermolecular interactions. By combining isothermal titration calorimetry with molecular modeling analysis, it was determined that the core material and the inner wall and the inner wall and the outer wall interact through intermolecular forces. Adenosine and hydroxypropyl-$\beta$-cyclodextrin form an optimal 1:1 complex through hydrophobic interactions, while hydroxypropyl-$\beta$-cyclodextrin and whey protein isolate interact through hydrogen bonds. The embedding rate of AD/Hp-$\beta$-CD/WPI microcapsules was 36.80%, and the 24 h retention rate under the release behavior test was 76.09%. The method of preparing adenosine microcapsules using composite wall materials is environmentally friendly and shows broad application prospects in storage and delivery systems with sustained release properties. Full article

(This article belongs to the Topic Challenges and Opportunities in Drug Delivery Research)

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