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4 Results Found

  • Article
  • Open Access
1,348 Views
16 Pages

Production and Characterization of a Novel Glycolipid Biosurfactant from Bradyrhizobium sp.

  • Marcos André Moura Dias,
  • Eduardo Luiz Rossini,
  • Douglas de Britto and
  • Marcia Nitschke

Biosurfactants (BS) are surface-active compounds synthesized by microorganisms with broad industrial applications. Although BS-producing strains are widely reported, little is known about their production by diazotrophic bacteria. This study investig...

  • Article
  • Open Access
28 Citations
7,164 Views
31 Pages

Combining OSMAC Approach and Untargeted Metabolomics for the Identification of New Glycolipids with Potent Antiviral Activity Produced by a Marine Rhodococcus

  • Fortunato Palma Esposito,
  • Rosa Giugliano,
  • Gerardo Della Sala,
  • Giovanni Andrea Vitale,
  • Carmine Buonocore,
  • Janardhan Ausuri,
  • Christian Galasso,
  • Daniela Coppola,
  • Gianluigi Franci and
  • Donatella de Pascale

22 August 2021

Natural products of microbial origin have inspired most of the commercial pharmaceuticals, especially those from Actinobacteria. However, the redundancy of molecules in the discovery process represents a serious issue. The untargeted approach, One St...

  • Review
  • Open Access
2,176 Views
19 Pages

Pharmaceutical scientists have researched the potential of secondary metabolites biosynthesized by microorganisms as active pharmaceutical ingredients (APIs) for the treatment of cancer. Ideally, these APIs should possess anticancer bioactivity that...

  • Article
  • Open Access
28 Citations
6,572 Views
23 Pages

Effects of Dispersants and Biosurfactants on Crude-Oil Biodegradation and Bacterial Community Succession

  • Gareth E. Thomas,
  • Jan L. Brant,
  • Pablo Campo,
  • Dave R. Clark,
  • Frederic Coulon,
  • Benjamin H. Gregson,
  • Terry J. McGenity and
  • Boyd A. McKew

This study evaluated the effects of three commercial dispersants (Finasol OSR 52, Slickgone NS, Superdispersant 25) and three biosurfactants (rhamnolipid, trehalolipid, sophorolipid) in crude-oil seawater microcosms. We analysed the crucial early bac...