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6 Results Found

  • Review
  • Open Access
14 Citations
3,594 Views
15 Pages

Smart Nucleic Acid Hydrogels with High Stimuli-Responsiveness in Biomedical Fields

  • Jie Li,
  • Yangzi Zhang,
  • Longjiao Zhu,
  • Keren Chen,
  • Xiangyang Li and
  • Wentao Xu

19 January 2022

Due to their hydrophilic, biocompatible and adjustability properties, hydrogels have received a lot of attention. The introduction of nucleic acids has made hydrogels highly stimuli-responsiveness and they have become a new generation of intelligent...

  • Review
  • Open Access
1,072 Views
34 Pages

Smart Nucleic Acid Hydrogel-Based Biosensors: From Molecular Recognition and Responsive Mechanisms to Applications

  • Lu Xu,
  • Longjiao Zhu,
  • Xiaoyu Wang,
  • Wenqiang Zhang,
  • Xiaoyun He,
  • Yangzi Zhang and
  • Wentao Xu

5 December 2025

Smart nucleic acid hydrogels (SNAHs), endowed with stimulus responsiveness, function as programmable molecular switches that can perceive diverse external stimuli and undergo rapid, reversible, and highly specific conformational or performance change...

  • Review
  • Open Access
32 Citations
5,446 Views
30 Pages

Stimulus-Responsive DNA Hydrogel Biosensors for Food Safety Detection

  • Huiyuan Wang,
  • Xinyu Wang,
  • Keqiang Lai and
  • Juan Yan

24 February 2023

Food safety has always been a major global challenge to human health and the effective detection of harmful substances in food can reduce the risk to human health. However, the food industry has been plagued by a lack of effective and sensitive safet...

  • Review
  • Open Access
2 Citations
3,259 Views
52 Pages

Gene therapy is a groundbreaking strategy in regenerative medicine, enabling precise cellular behavior modulation for tissue repair. In situ nucleic acid delivery systems aim to directly deliver nucleic acids to target cells or tissues to realize loc...

  • Review
  • Open Access
9 Citations
5,521 Views
33 Pages

Hydrogels are hydrophilic polymer materials that provide a wide range of physicochemical properties as well as are highly biocompatible. Biomedical researchers are adapting these materials for the ever-increasing range of design options and potential...

  • Review
  • Open Access
4 Citations
3,627 Views
35 Pages

21 July 2025

Hydrogels have emerged as multifunctional biomaterials in cardiac surgery, offering promising solutions for myocardial regeneration, adhesion prevention, valve engineering, and localized drug and gene delivery. Their high water content, biocompatibil...