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1,302 Results Found

  • Article
  • Open Access
8 Citations
8,965 Views
26 Pages

Moles and Mole Control on British Farms, Amenities and Gardens after Strychnine Withdrawal

  • Sandra E. Baker,
  • Stephen A. Ellwood,
  • Paul J. Johnson and
  • David W. Macdonald

8 June 2016

Moles are considered pests in Britain, but this issue has been little studied. Lower welfare standards have been tolerated for moles than for most other managed wild mammal species, as use of both the controversial poison, strychnine, and unregulated...

(This article belongs to the Special Issue Ethical and Welfare Dimensions of the Management of Unwanted Wildlife)
  • Article
  • Open Access
4 Citations
3,424 Views
14 Pages

Diagnostic Utility of TSSC3 and RB1 Immunohistochemistry in Hydatidiform Mole

  • Wai Kit Chia,
  • Pik Yuen Chia,
  • Nor Haslinda Abdul Aziz,
  • Salwati Shuib and ,
  • Muaatamarulain Mustangin,
  • Yoke Kqueen Cheah,
  • Teck Yee Khong,
  • Yin Ping Wong and
  • Geok Chin Tan
  • + 4 authors+ 0 author

The general notion of complete hydatidiform moles is that most of them consist entirely of paternal DNA; hence, they do not express p57, a paternally imprinted gene. This forms the basis for the diagnosis of hydatidiform moles. There are about 38 pat...

(This article belongs to the Special Issue Reproductive Immunology and Pregnancy 3.0)
  • Article
  • Open Access
5 Citations
5,787 Views
13 Pages

Nutritional and Nutraceutical Properties of Mexican Traditional Mole Sauce

  • Rafael Campos-Montiel,
  • Gabriela Medina-Pérez,
  • Edgar Vázquez-Nuñez,
  • Laura Afanador-Barajas and ,
  • Iridiam Hernández-Soto,
  • Gulzar Ahmad Nayik,
  • Lucio González-Montiel and
  • Mohamed Alkafafy
  • + 3 authors+ 0 author

31 January 2022

Mole sauce is one of the traditional Mexican foods; it is a complex mixture of ingredients of diverse origins that directly influence its nutritional value. The objective of this study was to investigate the antioxidant properties and nutritional com...

(This article belongs to the Special Issue Bioactive Compounds and Antioxidant Activity of Extracts from Different Natural Plants)
  • Review
  • Open Access
4 Citations
30,381 Views
21 Pages

Diagnosis and Surgical Treatment of Hydatidiform Mole

  • Antônio Braga,
  • Marcela Chagas,
  • Manisha Asrani,
  • Juliana Pereira Soares and ,
  • Sue Yazaki Sun,
  • Edward Araujo Júnior,
  • Rosiane Mattar,
  • Joffre Amim Junior,
  • Jorge Rezende-Filho and
  • Ross S. Berkowitz
  • + 6 authors+ 1 author

18 August 2025

Hydatidiform mole is a trophoblastic disorder resulting from abnormal fertilization. Diagnosis is established through a combination of clinical findings, elevated serum human chorionic gonadotropin (hCG) levels, and characteristic features on transva...

(This article belongs to the Special Issue Diagnostic Advances in Obstetrics and Gynecology, Breast Disease and Women’s Health)
  • Article
  • Open Access
913 Views
12 Pages

Tactile Sensing During Backward Locomotion in the Mole Cricket

  • Avi Amir,
  • Omer Yuval,
  • Kobi Fuxman,
  • Dafna Cohen and
  • Amir Ayali

29 May 2026

Subterranean locomotion challenges animals to maintain orientation and efficiently navigate confined spaces where vision is limited and local geometry is uncertain. Mole crickets (Gryllotalpidae), which regularly travel through self-excavated tunnels...

(This article belongs to the Special Issue Insects Sensory Ecology: From Natural Environments to Neural Mechanisms)
  • Article
  • Open Access
8 Citations
3,217 Views
15 Pages

10 February 2023

Lateralization is the functional control of certain behaviors in the brain being processed by either the left or right hemisphere. Behavioral asymmetries can occur at an individual and population level, although population-level lateralization is les...

(This article belongs to the Special Issue Physiology and Behaviour of African Mole-Rats)
  • Article
  • Open Access
14 Citations
3,145 Views
10 Pages

Academ Virus, a Novel Hantavirus in the Siberian Mole (Talpa altaica) from Russia

  • Liudmila N. Yashina,
  • Victor V. Panov,
  • Sergey A. Abramov,
  • Natalia A. Smetannikova and ,
  • Ekaterina M. Luchnikova,
  • Tamara A. Dupal,
  • Anton V. Krivopalov,
  • Satoru Arai and
  • Richard Yanagihara
  • + 4 authors+ 0 author

2 February 2022

To date, six hantavirus species have been detected in moles (family Talpidae). In this report, we describe Academ virus (ACDV), a novel hantavirus harbored by the Siberian mole (Talpa altaica) in Western Siberia. Genetic analysis of the complete S-,...

(This article belongs to the Special Issue Hantavirus)
  • Article
  • Open Access
4 Citations
3,970 Views
13 Pages

Phylogeny of Shrew- and Mole-Borne Hantaviruses in Poland and Ukraine

  • Fuka Kikuchi,
  • Satoru Arai,
  • Janusz Hejduk,
  • Ai Hayashi and ,
  • Janusz Markowski,
  • Marcin Markowski,
  • Leszek Rychlik,
  • Vasyl Khodzinskyi,
  • Hajime Kamiya and
  • Richard Yanagihara
  • + 9 authors+ 4 authors

29 March 2023

Earlier, we demonstrated the co-circulation of genetically distinct non-rodent-borne hantaviruses, including Boginia virus (BOGV) in the Eurasian water shrew (Neomys fodiens), Seewis virus (SWSV) in the Eurasian common shrew (Sorex araneus) and Nova...

(This article belongs to the Special Issue State-of-the-Art Animal Virus Research in Poland II)
  • Review
  • Open Access
9 Citations
8,198 Views
12 Pages

Hydatidiform Mole—Between Chromosomal Abnormality, Uniparental Disomy and Monogenic Variants: A Narrative Review

  • Andreea Florea,
  • Lavinia Caba,
  • Ana-Maria Grigore,
  • Lucian-Mihai Antoci and ,
  • Mihaela Grigore,
  • Mihaela I. Gramescu and
  • Eusebiu Vlad Gorduza
  • + 2 authors+ 0 author

10 December 2023

A hydatidiform mole (HM) or molar pregnancy is the most common benign form of gestational trophoblastic disease characterized by a proliferation of the trophoblastic epithelium and villous edema. Hydatidiform moles are classified into two forms: comp...

(This article belongs to the Special Issue Obstetrics and Gynecology Medicine: Go From Bench to Bedside)
  • Article
  • Open Access
1 Citations
3,397 Views
21 Pages

Spectroscopic Analysis of the Extracellular Matrix in Naked Mole-Rat Temporomandibular Joints

  • Tetsuya Adachi,
  • Hayata Imamura,
  • Toyonari Yaji,
  • Kentaro Mochizuki and ,
  • Wenliang Zhu,
  • Satoru Shindo,
  • Shunichi Shibata,
  • Keiji Adachi,
  • Toshiro Yamamoto and
  • Giuseppe Pezzotti
  • + 9 authors+ 4 authors

30 May 2025

Naked mole-rats are extremely long-living rodents with a maximum lifespan of 37 years, and their cellular aging and tissue aging are almost nonexistent. Therefore, in this study, we aim to analyze the extracellular matrix of the temporomandibular joi...

(This article belongs to the Special Issue Hydrogels with Appropriate/Tunable Properties for Biomedical Applications (3rd Edition))
  • Article
  • Open Access
3,841 Views
11 Pages

Mole Fraction Dependent Passive Voltage Amplification in FE-DE Heterostructure

  • Archana Chamarahalli Manjunatha,
  • Pratheeksha Suresh,
  • Akshatha Bhat,
  • Vikash Mishra and ,
  • Yashwanth Nanjappa,
  • Bhaskar Awadhiya and
  • Sachin Agrawal
  • + 2 authors+ 0 author

This paper explores ferroelectric–dielectric heterostructures comprising a ferroelectric oxide (Lead Zirconium Titanate (PbZr1−xTix O3)) with a varying mole fraction and a fixed dielectric oxide (Silicon dioxide (SiO2)). The study ai...

  • Article
  • Open Access
3 Citations
5,783 Views
15 Pages

Simulation Study on the Influence of Gas Mole Fraction and Aqueous Activity under Phase Equilibrium

  • Weilong Zhao,
  • Hao Wu,
  • Jing Wen,
  • Xin Guo and ,
  • Yongsheng Zhang and
  • Ruirui Wang
  • + 1 author+ 0 author

22 January 2019

This work explored the influence of gas mole fraction and activity in aqueous phase while predicting phase equilibrium conditions. In pure gas systems, such as CH4, CO2, N2 and O2, the gas mole fraction in aqueous phase as one of phase equilibrium co...

(This article belongs to the Special Issue Gas Capture Processes)
  • Article
  • Open Access
15 Citations
3,570 Views
15 Pages

Effect of Oxygen Mole Fraction on Static Properties of Pressure-Sensitive Paint

  • Tomohiro Okudera,
  • Takayuki Nagata,
  • Miku Kasai,
  • Yuji Saito and ,
  • Taku Nonomura and
  • Keisuke Asai
  • + 1 author+ 0 author

4 February 2021

The effects of the oxygen mole fraction on the static properties of pressure-sensitive paint (PSP) were investigated. Sample coupon tests using a calibration chamber were conducted for poly(hexafluoroisopropyl methacrylate)-based PSP (PHFIPM-PSP), po...

(This article belongs to the Special Issue Optical Sensors for Flow Diagnostics)
  • Case Report
  • Open Access
3,711 Views
10 Pages

A Partial Hydatidiform Mole in an Ovarian Ectopic Pregnancy: An Exceptional Occurrence

  • Maria Paola Bonasoni,
  • Roberta Zuntini,
  • Khush Shah,
  • Loredana De Marco and ,
  • Eleonora Zanetti,
  • Luca Pagliai,
  • Immacolata Blasi,
  • Emanuela Carossino,
  • Alice Ferretti and
  • Lorenzo Aguzzoli
  • + 6 authors+ 1 author

13 August 2025

Background and Clinical Significance: Ovarian ectopic pregnancy (OEP) is a rare occurrence, and molar degeneration is even more exceptional. Differential diagnosis between a partial and complete hydatidiform mole is paramount as the complete type car...

(This article belongs to the Section Pathology and Molecular Diagnostics)
  • Article
  • Open Access
2,930 Views
21 Pages

Spectroscopic Analysis of the Extracellular Matrix Hierarchical Structure in Naked Mole-Rat Skin

  • Tetsuya Adachi,
  • Hayata Imamura,
  • Risa Tamagawa-Mineoka,
  • Toyonari Yaji and ,
  • Makoto Kawano,
  • Shigenori Itsuzaki,
  • Keiji Adachi,
  • Fumishige Oseko,
  • Shunichi Shibata and
  • Giuseppe Pezzotti
  • + 11 authors+ 6 authors

1 April 2026

Naked mole-rats are extremely long-lived rodents with a lifespan of up to 40 years, during which cellular and tissue aging is rarely observed. In this study, we analyzed the extracellular matrix (ECM) of naked mole-rat skin at the molecular level to...

(This article belongs to the Special Issue Gels with Health-Promoting Properties)
  • Article
  • Open Access
1 Citations
13,397 Views
24 Pages

14 December 2024

In this paper, we analyse the attitudes and sentiments of Romanian smallholders towards mole infestations, as expressed in online contexts. A corpus of texts on the topic of ground moles and how to get rid of them was collected from social media and...

(This article belongs to the Section Human-Animal Interactions, Animal Behaviour and Emotion)
  • Case Report
  • Open Access
1 Citations
2,859 Views
12 Pages

Complete Hydatiform Mole with a Coexisting Living Fetus: A Case Report

  • Irene Piccolotti,
  • Silvia Zago,
  • Maria Paola Bonasoni,
  • Beatrice Rosignoli and ,
  • Annachiara Boschi,
  • Francesca Lostritto,
  • Francesco Catania and
  • Tiziana Arcangeli
  • + 3 authors+ 0 author

Background: Gestational trophoblastic diseases comprise the hydatiform moles (HMs), complete or partial, an abnormal development of trophoblastic tissue. HMs derive from a gametogenesis error during conception leading to an anomalous chromosomal asse...

(This article belongs to the Section Perinatal and Neonatal Medicine)
  • Review
  • Open Access
1 Citations
2,316 Views
9 Pages

Background/Objectives: Subterranean mole-rats live in an intricate system of underground tunnels, a unique acoustic environment that has led to adaptations to their hearing. Most experimenters have concluded that mole-rats have poor hearing threshold...

  • Review
  • Open Access
8 Citations
30,278 Views
11 Pages

DNA Homeostasis and Senescence: Lessons from the Naked Mole Rat

  • Harvey Boughey,
  • Mateusz Jurga and
  • Sherif F. El-Khamisy

As we age, our bodies accrue damage in the form of DNA mutations. These mutations lead to the generation of sub-optimal proteins, resulting in inadequate cellular homeostasis and senescence. The build-up of senescent cells negatively affects the loca...

(This article belongs to the Special Issue Genome Stability and Neurological Disease)
  • Article
  • Open Access
26 Citations
4,113 Views
13 Pages

Chromosome Translocations as a Driver of Diversification in Mole Voles Ellobius (Rodentia, Mammalia)

  • Svetlana A. Romanenko,
  • Elena A. Lyapunova,
  • Abdusattor S. Saidov,
  • Patricia C.M. O’Brien and ,
  • Natalia A. Serdyukova,
  • Malcolm A. Ferguson-Smith,
  • Alexander S. Graphodatsky and
  • Irina Bakloushinskaya
  • + 3 authors+ 0 author

10 September 2019

The involvement of chromosome changes in the initial steps of speciation is controversial. Here we examine diversification trends within the mole voles Ellobius, a group of subterranean rodents. The first description of their chromosome variability w...

(This article belongs to the Special Issue Chromosome and Karyotype Variation)
  • Review
  • Open Access
11 Citations
10,291 Views
20 Pages

24 February 2023

Naked mole-rats (Heterocephalus glaber) are very unusual among subterranean mammals in that they live in large colonies and are extremely social, spending large amounts of time gathered together in underground nests more than a meter below the surfac...

(This article belongs to the Special Issue Physiology and Behaviour of African Mole-Rats)
  • Article
  • Open Access
5 Citations
2,886 Views
20 Pages

Evolution of Atmospheric Carbon Dioxide and Methane Mole Fractions in the Yangtze River Delta, China

  • Kai Jiang,
  • Qianli Ma,
  • Kunpeng Zang,
  • Yi Lin and ,
  • Yuanyuan Chen,
  • Shuo Liu,
  • Xuemei Qing,
  • Shanshan Qiu,
  • Haoyu Xiong and
  • Shuangxi Fang
  • + 7 authors+ 2 authors

16 August 2023

As the most economically developed region in China, the Yangtze River Delta (YRD) region contributed to ~17% of the total anthropogenic CO2 emissions from China. However, the studies of atmospheric CO2 and CH4 in this area are relatively sparse and u...

(This article belongs to the Section Air Quality)
  • Article
  • Open Access
6 Citations
3,770 Views
17 Pages

1 April 2022

Carbon dioxide (CO2) and methane (CH4) are the two major radiative forcing factors of greenhouse gases. In this study, surface and column mole fractions of CO2 and CH4 were first measured at a desert site in Dunhuang, west China. The average column m...

(This article belongs to the Special Issue Novel Techniques for Measuring Greenhouse Gases)
  • Article
  • Open Access
4 Citations
2,378 Views
12 Pages

Non-Invasive Quantification of Faecal and Urine Reproductive Hormone Metabolites in the Naked Mole-Rat (Heterocephalus glaber)

  • Tshepiso Lesedi Majelantle,
  • Andre Ganswindt,
  • Stefanie Birgit Ganswindt,
  • Nicole Hagenah and ,
  • Daniel William Hart and
  • Nigel Charles Bennett
  • + 1 author+ 0 author

27 September 2023

The naked mole-rat (Heterocephalus glaber) occurs in colonies with a distinct dominance hierarchy, including one dominant, breeding female (the queen), 1–3 breeding males, and non-reproductive subordinates of both sexes that are reproductively...

(This article belongs to the Special Issue Physiology and Behaviour of African Mole-Rats)
  • Article
  • Open Access
6 Citations
4,712 Views
9 Pages

Accessing Mole-Scanning through Community Pharmacy: A Pilot Service in Collaboration with Dermatology Specialists

  • Charlotte L. Kirkdale,
  • Zoe Archer,
  • Tracey Thornley,
  • David Wright and ,
  • Mette Valeur,
  • Nicola Gourlay and
  • Kurt Ayerst
  • + 2 authors+ 0 author

3 December 2020

Early identification and treatment of malignant melanoma is crucial to prevent mortality. The aim of this work was to describe the uptake, profile of users and service outcomes of a mole scanning service in the community pharmacy setting in the UK. I...

  • Article
  • Open Access
13 Citations
6,124 Views
11 Pages

Delayed Onset of Age-Dependent Changes in Ultrastructure of Myocardial Mitochondria as One of the Neotenic Features in Naked Mole Rats (Heterocephalus glaber)

  • Lora Bakeeva,
  • Valeria Vays,
  • Irina Vangeli,
  • Chupalav Eldarov and ,
  • Susanne Holtze,
  • Thomas Hildebrandt and
  • Vladimir Skulachev
  • + 2 authors+ 0 author

In this study, the ultrastructure of mitochondria in cardiomyocytes of naked mole rats (Heterocephalus glaber) aged from 6 months to 11 years was examined. Mitochondria in cardiomyocytes of naked mole rats have a specific ultrastructure that is diffe...

(This article belongs to the Special Issue The Impact of Aging on Cardio and Cerebrovascular Diseases)
  • Systematic Review
  • Open Access
3 Citations
2,927 Views
17 Pages

Hydatidiform Mole with Coexisting Normal Pregnancy: A Systematic Review and Individual Participant Data Meta-Analysis

  • Pier Carlo Zorzato,
  • Alberta Ricci,
  • Mariachiara Bosco,
  • Liliana Galli and ,
  • Laura Luka,
  • Irene Porcari,
  • Rosa Maria Laterza,
  • Veronica Parolin,
  • Michele Milella and
  • Simone Garzon
  • + 10 authors+ 5 authors

1 October 2025

Background and Objectives: This study aimed to evaluate obstetric, neonatal, and oncologic outcomes of pregnancies complicated by a hydatidiform mole coexisting with a live fetus (HMCF) carried beyond viability, and to assess the impact of delivery m...

(This article belongs to the Section Obstetrics and Gynecology)
  • Article
  • Open Access
8 Citations
1,610 Views
23 Pages

Structural Design and Analysis of Bionic Shovel Based on the Geometry of Mole Cricket Forefoot

  • Shengbo Lin,
  • Hongyan Sun,
  • Guangen Yan,
  • Kexin Que and ,
  • Sijia Xu,
  • Zhong Tang,
  • Guoqiang Wang and
  • Jiali Li
  • + 3 authors+ 0 author

In the mechanized harvesting of root vegetables, loosening is a key factor that restricts harvesting efficiency. Existing mechanical loosening methods have poor loosening effect and high operational resistance. Therefore, more efficient agricultural...

(This article belongs to the Section Agricultural Technology)
  • Article
  • Open Access
10 Citations
5,427 Views
15 Pages

Aggression, Boldness, and Exploration Personality Traits in the Subterranean Naked Mole-Rat (Heterocephalus glaber) Disperser Morphs

  • Tshepiso Lesedi Majelantle,
  • Andre Ganswindt,
  • Christian Walter Werner Pirk,
  • Nigel Charles Bennett and
  • Daniel William Hart

9 November 2022

Animal personality traits (consistent behavioral differences between individuals in their behavior across time and/or situation) affect individual fitness through facets, such as dispersal. In eusocial naked mole-rat (Heterocephalus glaber) colonies,...

(This article belongs to the Special Issue Physiology and Behaviour of African Mole-Rats)
  • Article
  • Open Access
27 Citations
3,474 Views
25 Pages

10 December 2024

Modern technologies, particularly artificial intelligence methods such as machine learning, hold immense potential for supporting doctors with cancer diagnostics. This study explores the enhancement of popular machine learning methods using a bio-ins...

(This article belongs to the Special Issue Novel Approaches to Machine Learning and Artificial Intelligence in Cancer Research and Care)
  • Article
  • Open Access
30 Citations
5,998 Views
20 Pages

29 October 2019

Naked mole-rats are long-lived animals that show unusual resistance to hypoxia, cancer and ageing. Protein deimination is an irreversible post-translational modification caused by the peptidylarginine deiminase (PAD) family of enzymes, which convert...

(This article belongs to the Special Issue Peptidylarginine Deiminases and Protein Deimination in Health and Disease)
  • Case Report
  • Open Access
3 Citations
4,795 Views
9 Pages

Twin pregnancy with a complete hydatidiform mole and coexisting fetus (CHMCF) is an exceedingly rare condition with an incidence of about 1 in 20,000–100,000 pregnancies. It can be detected by prenatal ultrasonography and an elevated maternal s...

(This article belongs to the Special Issue Pathology and Diagnosis of Gynecologic Diseases)
  • Feature Paper
  • Article
  • Open Access
4,542 Views
12 Pages

8 February 2018

In Hans Sahl’s poem “Der Maulwurf” (The Mole), only the title gives an indication about the speaker’s species affiliation. The speaker of the poem suggests that he was transformed from a human into an animal. This metamorphosis is not only physical,...

(This article belongs to the Special Issue Animal Narratology)
  • Review
  • Open Access
22 Citations
22,750 Views
13 Pages

Gestational Trophoblastic Disease: Complete versus Partial Hydatidiform Moles

  • Jeffrey Gonzalez,
  • Meagan Popp,
  • Stephanie Ocejo,
  • Alvaro Abreu and ,
  • Hisham F. Bahmad and
  • Robert Poppiti
  • + 1 author+ 0 author

17 July 2024

Hydatidiform moles, including both complete and partial moles, constitute a subset of gestational trophoblastic diseases characterized by abnormal fertilization resulting in villous hydrops and trophoblastic hyperplasia with or without embryonic deve...

  • Communication
  • Open Access
2,763 Views
12 Pages

26 July 2024

Here, for the first time, the structure of genes involved in sex determination in mammals (full Sry and partial Rspo1, Eif2s3x, and Eif2s3y) was analyzed for the European mole Talpa europaea with ovotestes in females. We confirmed male-specificity fo...

(This article belongs to the Section Animal Genetics and Genomics)
  • Article
  • Open Access
58 Citations
4,303 Views
18 Pages

Optimization of FFF Process Parameters by Naked Mole-Rat Algorithms with Enhanced Exploration and Exploitation Capabilities

  • Jasgurpreet Singh Chohan,
  • Nitin Mittal,
  • Raman Kumar,
  • Sandeep Singh and ,
  • Shubham Sharma,
  • Shashi Prakash Dwivedi,
  • Ambuj Saxena,
  • Somnath Chattopadhyaya,
  • Rushdan A. Ilyas and
  • Szymon Wojciechowski
  • + 6 authors+ 1 author

23 May 2021

Fused filament fabrication (FFF) has numerous process parameters that influence the mechanical strength of parts. Hence, many optimization studies are performed using conventional tools and algorithms. Although studies have also been performed using...

(This article belongs to the Special Issue Additive Manufacturing of Bio and Synthetic Polymers)
  • Article
  • Open Access
3 Citations
4,449 Views
15 Pages

Pup Recruitment in a Eusocial Mammal—Which Factors Influence Early Pup Survival in Naked Mole-Rats?

  • Michaela Wetzel,
  • Alexandre Courtiol,
  • Heribert Hofer,
  • Susanne Holtze and
  • Thomas B. Hildebrandt

11 February 2023

In eusocial insects, offspring survival strongly depends on the quality and quantity of non-breeders. In contrast, the influence of social factors on offspring survival is more variable in cooperatively breeding mammals since maternal traits also pla...

(This article belongs to the Special Issue Physiology and Behaviour of African Mole-Rats)
  • Article
  • Open Access
8 Citations
3,993 Views
15 Pages

Unique Features of the Tissue Structure in the Naked Mole Rat (Heterocephalus glaber): Hypertrophy of the Endoplasmic Reticulum and Spatial Mitochondrial Rearrangements in Hepatocytes

  • Valeriya Vays,
  • Irina Vangeli,
  • Chupalav Eldarov,
  • Vasily Popkov and ,
  • Susanne Holtze,
  • Thomas Hildebrandt,
  • Olga Averina,
  • Dmitry Zorov and
  • Lora Bakeeva
  • + 4 authors+ 0 author

13 August 2022

The reason for the exceptional longevity of the naked mole rat (Heterocephalus glaber) remains a mystery to researchers. We assumed that evolutionarily, H. glaber acquired the ability to quickly stabilize the functioning of mitochondria and endoplasm...

(This article belongs to the Special Issue Liver Damage and Repair 2.0)
  • Article
  • Open Access
30 Citations
4,047 Views
20 Pages

3D Finite Element Simulation and Experimental Validation of a Mole Rat’s Digit Inspired Biomimetic Potato Digging Shovel

  • Jiangtao Yu,
  • Yunhai Ma,
  • Shuo Wang,
  • Zihe Xu and ,
  • Xuanting Liu,
  • Hubiao Wang,
  • Hongyan Qi,
  • Lijun Han and
  • Jian Zhuang
  • + 4 authors+ 0 author

8 February 2022

To reduce the draught force of a traditional planar potato digging shovel (DZ), a biomimetic potato digging shovel (YS), inspired by the mole rat’s digits, is designed, using the biomimetic macroscopic surface modification method. The finite el...

(This article belongs to the Section Mechanical Engineering)
  • Article
  • Open Access
5 Citations
5,487 Views
12 Pages

Initial Treatment and Outcomes of Complete Hydatidiform Mole in Women 40 Years or Older: A Multicenter Cohort Study

  • Cecília Canêdo Freitas Desmarais,
  • Izildinha Maestá,
  • Sue Yazaki Sun,
  • Jorge de Rezende-Filho and ,
  • Roberto Antonio de Araújo Costa,
  • Lawrence Hsu Lin,
  • Mariza Branco-Silva,
  • Neil S. Horowitz,
  • Kevin M. Elias and
  • Ross S. Berkowitz
  • + 6 authors+ 1 author

26 September 2025

Objectives: To evaluate the potential associations of the type of complete hydatidiform mole (CHM) initial treatment (hysterectomy or uterine evacuation) with GTN development, need for chemotherapy, and treatment outcome in women aged ≥ 40 years....

(This article belongs to the Section Methods and Technologies Development)
  • Review
  • Open Access
721 Views
23 Pages

24 July 2026

Background/Objectives: Biallelic mutations of NLRP7, a maternal-effect gene encoding a key component of the subcortical maternal complex, are the major monogenic cause of recurrent hydatidiform mole (RHM) and confer a substantial lifetime risk of ges...

(This article belongs to the Special Issue Primary and Recurrent Gynecological Cancer: Epidemiology, Management and New Therapies)
  • Article
  • Open Access
21 Citations
7,544 Views
11 Pages

Map-A-Mole: Greenspace Area Influences the Presence and Abundance of the European Mole Talpa europaea in Urban Habitats

  • Mark D.E. Fellowes,
  • Kojo Acquaah-Harrison,
  • Fabio Angeoletto,
  • Jeater W.M.C. Santos and ,
  • Deleon da Silva Leandro,
  • Elise A. Rocha,
  • Tara J. Pirie and
  • Rebecca L. Thomas
  • + 3 authors+ 0 author

25 June 2020

The European mole Talpa europaea is common across much of Britain. It has a unique fossorial lifestyle, and evidence of its presence is readily identified through the presence of characteristic molehills. Although molehills are often a common sight i...

(This article belongs to the Special Issue Anthropogenic Impacts on Urban Mammals)
  • Article
  • Open Access
1 Citations
1,136 Views
14 Pages

Comparison of MOLES and MelAInoma for Differentiating Small Choroidal Melanomas from Nevi

  • Katerina Stripling,
  • Hannah Coudé Adam,
  • Mats Holmström and
  • Gustav Stålhammar

3 March 2026

Background: Early identification of small choroidal melanomas is important, as metastatic risk increases with tumor size. However, distinguishing small melanomas from benign choroidal nevi is challenging and may lead to unnecessary referrals and over...

(This article belongs to the Special Issue Artificial Intelligence in Ocular Oncology)
  • Article
  • Open Access
3 Citations
4,676 Views
15 Pages

End-User Skin Analysis (Moles) through Image Acquisition and Processing System

  • Lorant Andras Szolga,
  • Denisa Alice Bozga and
  • Camelia Florea

1 February 2022

Skin moles and lesions can be the first signs of severe skin diseases such as cancer. This paper presents the development of an end-user device capable of capturing images, segmentation and diagnosis of moles by using the ABCD rule, which stands for...

(This article belongs to the Special Issue Smart Healthcare Systems Based on the Internet of Things and Artificial Intelligence)
  • Article
  • Open Access
4 Citations
2,929 Views
16 Pages

Validation of Enzyme Immunoassays via an Adrenocorticotrophic Stimulation Test for the Non-Invasive Quantification of Stress-Related Hormone Metabolites in Naked Mole-Rats

  • Tshepiso Lesedi Majelantle,
  • Nigel Charles Bennett,
  • Stefanie Birgit Ganswindt,
  • Daniel William Hart and
  • Andre Ganswindt

21 April 2023

Small size in mammals usually restricts long-term, frequent monitoring of endocrine function using plasma as a matrix. Thus, the non-invasive monitoring of hormone metabolite concentrations in excreta may provide an invaluable approach. The aim of th...

(This article belongs to the Special Issue Non-invasive Methods of Stress Monitoring in Animals under Human Care)
  • Article
  • Open Access
1 Citations
3,576 Views
9 Pages

The European mole (Talpa europaea) has a widespread distribution throughout Europe. However, little is known about the presence of zoonotic pathogens in European moles. We therefore tested 180 moles from the middle and the south of the Netherlands by...

(This article belongs to the Special Issue Advanced Research on Ticks and Tick-Borne Diseases)
  • Article
  • Open Access
7 Citations
4,649 Views
13 Pages

Attenuated Replication-Competent Herpes Simplex Virus Expressing an ECM-Modifying Transgene Hyaluronan Synthase 2 of Naked Mole Rat in Oncolytic Gene Therapy

  • Jussi Palomäki,
  • Kiira Kalke,
  • Julius Orpana,
  • Liisa Lund and ,
  • Fanny Frejborg,
  • Henrik Paavilainen,
  • Hannu Järveläinen and
  • Veijo Hukkanen
  • + 3 authors+ 0 author

Herpes simplex virus (HSV) has proven successful in treating human cancer. Since the approval of talimogene laherparepvec (T-VEC) in 2015, HSV has been thoroughly researched to discover novel mechanisms to combat cancer and treat other diseases. Anot...

(This article belongs to the Special Issue Herpes Simplex Virus (HSV))
  • Article
  • Open Access
1 Citations
2,377 Views
18 Pages

Hydatidiform Moles: The Contribution of Ancillary Techniques in Refining Their Histopathological Diagnosis

  • Teodora Ana Balan,
  • Raluca Anca Balan,
  • Cornelia Amalinei,
  • Simona Eliza Giușcă and
  • Irina-Draga Căruntu

23 December 2025

A hydatidiform mole (HM) is the most common form of gestational trophoblastic disease (GTD). Differentiating hydatidiform moles (HMs) from non-molar pregnancies and distinguishing complete HMs (CHMs) from partial HMs (PHMs) remains challenging due to...

(This article belongs to the Special Issue Insights in Reproductive Immunology and Placental Pathology, 2nd Edition)
  • Article
  • Open Access
1 Citations
1,282 Views
18 Pages

This study investigates the impact of golden moles (Amblysomus sp.) on the abundance, diversity, and community structure of nematodes in kweek grass (Cynodon dactylon) within the Sovenga Hills of Limpopo Province, South Africa. Eight sites were sampl...

(This article belongs to the Section Agricultural Soils)
  • Article
  • Open Access
10 Citations
8,267 Views
13 Pages

CO2 Monitoring and Background Mole Fraction at Zhongshan Station, Antarctica

  • Yulong Sun,
  • Lingen Bian,
  • Jie Tang,
  • Zhiqiu Gao and ,
  • Changgui Lu and
  • Russell C. Schnell
  • + 1 author+ 0 author

24 September 2014

Background CO2 mole fraction and seasonal variations, measured at Zhongshan station, Antarctica, for 2010 through 2013, exhibit the expected lowest mole fraction in March with a peak in November. Irrespective of wind direction, the mole fraction of C...

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