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Article

3 Citations

3,013 Views

21 Pages

Genomes of Endotrypanum monterogeii from Panama and Zelonia costaricensis from Brazil: Expansion of Multigene Families in Leishmaniinae Parasites That Are Close Relatives of Leishmania spp.

Percy O. Tullume-Vergara,
Kelly Y. O. Caicedo,
Jose F. C. Tantalean,
Myrna G. Serrano,
Gregory A. Buck,
Marta M. G. Teixeira,
Jeffrey J. Shaw and
Joao M. P. Alves

Pathogens2023, 12(12), 1409;https://doi.org/10.3390/pathogens12121409

30 November 2023

The Leishmaniinae subfamily of the Trypanosomatidae contains both genus Zelonia (monoxenous) and Endotrypanum (dixenous). They are amongst the nearest known relatives of Leishmania, which comprises many human pathogens widespread in the developing wo...

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Article

1 Citations

1,449 Views

13 Pages

Experimental Susceptibility of Nyssomyia antunesi and Lutzomyia longipalpis (Psychodidae: Phlebotominae) to Leishmania (Viannia) lainsoni and L. (V.) lindenbergi (Trypanosomatidae: Leishmaniinae)

Yetsenia del Valle Sánchez Uzcátegui,
Fernando Tobias Silveira,
Thais Gouvea de Morais,
Rodrigo Ribeiro Furtado,
Thiago Vasconcelos dos Santos and
Marinete Marins Póvoa

Microorganisms2024, 12(4), 809;https://doi.org/10.3390/microorganisms12040809

17 April 2024

The present work assessed the experimental susceptibility of Nyssomyia antunesi and Lutzomyia longipalpis to Leishmania (Viannia) lainsoni and L. (V.) lindenbergi. A L. (Leishmania) chagasi–Lu. longipalpis combination was used as a susceptible...

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Article

18 Citations

5,627 Views

20 Pages

Genome Analysis of Endotrypanum and Porcisia spp., Closest Phylogenetic Relatives of Leishmania, Highlights the Role of Amastins in Shaping Pathogenicity

Amanda T. S. Albanaz,
Evgeny S. Gerasimov,
Jeffrey J. Shaw,
Jovana Sádlová,
Julius Lukeš,
Petr Volf,
Fred R. Opperdoes,
Alexei Y. Kostygov,
Anzhelika Butenko and
Vyacheslav Yurchenko

Genes2021, 12(3), 444;https://doi.org/10.3390/genes12030444

20 March 2021

While numerous genomes of Leishmania spp. have been sequenced and analyzed, an understanding of the evolutionary history of these organisms remains limited due to the unavailability of the sequence data for their closest known relatives, Endotrypanum...

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Editorial

2 Citations

1,876 Views

5 Pages

Spotlight on Leishmaniasis Research: Insights from the Special Issue “Emerging Topics in Leishmaniasis Research”

Sandra Regina Maruyama

Trop. Med. Infect. Dis.2024, 9(9), 200;https://doi.org/10.3390/tropicalmed9090200

2 September 2024

Leishmaniases, caused by dixenous trypanosomatids from the Leishmaniinae subfamily (over 20 Leishmania species), manifest in three primary clinical forms: visceral (VL), cutaneous (CL), and mucocutaneous (MCL) [...]

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Review

20 Citations

4,610 Views

15 Pages

The Maze Pathway of Coevolution: A Critical Review over the Leishmania and Its Endosymbiotic History

Lilian Motta Cantanhêde,
Carlos Mata-Somarribas,
Khaled Chourabi,
Gabriela Pereira da Silva,
Bruna Dias das Chagas,
Luiza de Oliveira R. Pereira,
Mariana Côrtes Boité and
Elisa Cupolillo

Genes2021, 12(5), 657;https://doi.org/10.3390/genes12050657

27 April 2021

The description of the genus Leishmania as the causative agent of leishmaniasis occurred in the modern age. However, evolutionary studies suggest that the origin of Leishmania can be traced back to the Mesozoic era. Subsequently, during its evolution...

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