Search Results (2,267)

At present, pedestrian navigation systems using smartphones have become common in daily activities. For their ubiquitous, accurate, and reliable services, map information collection is essential for constructing comprehensive spatial databases. Previously, we have developed a map information collection tool to extract building information using Google Maps, optical character recognition (OCR), geolocation, and web scraping with smartphones. However, indoor navigation often suffers from inaccurate localization due to degraded GPS signals inside buildings and Simultaneous Localization and Mapping (SLAM) estimation errors, causing position errors and confusing augmented reality (AR) guidance. In this paper, we present an improved map information collection tool to address this problem. It captures 360° panoramic images to build 3D models, apply photogrammetry-based mesh reconstruction to correct geometry, and georeference point clouds to refine latitude–longitude coordinates. For evaluations, experiments in various indoor scenarios were conducted. The results demonstrate that the proposed method effectively mitigates positional errors with an average drift correction of 3.15 m, calculated via the Haversine formula. Geometric validation using point cloud analysis showed high registration accuracy, which translated to a 100% task completion rate and an average navigation time of 124.5 s among participants. Furthermore, usability testing using the System Usability Scale (SUS) yielded an average score of 96.5, categorizing the user interface as ’Best Imaginable’. These quantitative findings substantiate that the integration of 360° imaging and photogrammetric correction significantly enhances navigation reliability and user satisfaction compared with previous sensor fusion approaches. Full article

Vitamin D, a fat-soluble secosteroid traditionally recognized for skeletal health, exerts pleiotropic effects on cardiovascular physiology and disease. Circulating 25-hydroxyvitamin D [25(OH)D], the principal biomarker of vitamin D status, is frequently suboptimal worldwide, particularly in older adults, individuals with darker skin pigmentation, and populations at higher latitudes. Observational studies consistently associate low 25(OH)D concentrations with increased risk of hypertension, atherosclerosis, myocardial infarction, heart failure, arrhythmias, stroke, and cardiovascular mortality. Mechanistic investigations have revealed that vitamin D modulates cardiomyocyte calcium handling, endothelial function, vascular smooth muscle proliferation, inflammation, oxidative stress, and renin–angiotensin–aldosterone system activity, establishing biologically plausible links to cardiovascular outcomes. Despite these associations, large randomized trials of vitamin D supplementation have failed to demonstrate reductions in major cardiovascular events, likely due to heterogeneity in baseline status, dosing regimens, intervention timing, genetic variability, and underlying comorbidities. Vitamin D may function more effectively as a biomarker of cardiovascular risk rather than a universal therapeutic agent, with deficiency reflecting systemic vulnerability rather than acting as a dominant causal factor. Emerging evidence supports precision approaches targeting individuals with severe deficiency, high renin activity, early endothelial dysfunction, or specific genetic profiles, potentially in combination with lifestyle or pharmacologic interventions. Future research should focus on defining optimal dosing strategies, intervention timing, and mechanistic biomarkers to identify subpopulations most likely to benefit, integrating vitamin D therapy into multifaceted cardiovascular prevention frameworks. This systematic review synthesizes molecular, observational, and clinical trial evidence, critically evaluating the current understanding of vitamin D in cardiovascular medicine and highlighting opportunities for targeted, personalized interventions. Vitamin D represents a complex, context-dependent modulator of cardiovascular health, offering both prognostic insight and potential therapeutic value when appropriately applied. Full article

The Earth’s climate system exhibits nonlinear behavior driven by interactions among the atmosphere, oceans, cryosphere, land, and biosphere. These dynamics have given rise to relatively stable environments that shape the structure and function of the modern biosphere. This review is a primer for conservation practitioners and natural resource managers to develop a deep understanding of how the Earth System works. The key is to recognize that shifts in Earth System dynamics due to global climate change can destabilize the biosphere in unforeseen ways. The potential emergence of novel ecoregions must be a critical factor in adaptation planning for conservation and resource management. We review how thermodynamic constraints and global circulation dynamics determine the distribution of terrestrial and marine biomes. These dynamics stem from the Earth System functioning as a heat engine, transporting excess heat from low to high latitudes. We illustrate how biome climates are organized into climate regimes, with spatial and temporal characteristics linked to complex features of atmospheric and oceanic circulation. At centennial to millennial scales, these dynamics have created a stable envelope of natural variability in climate that has established a long-standing operating space for biota. However, this stability is becoming increasingly uncertain due to the growing positive energy imbalance in the Earth System primarily driven by anthropogenic greenhouse gas emissions. This forcing is leading to disruptive climatic change, putting the biosphere on a trajectory toward new transient states. Such global to regional climatic instability and biospheric restructuring introduce a high level of uncertainty in ecological futures, with major implications for natural resource management, biodiversity conservation strategies, and societal adaptation. We conclude by discussing frameworks for impact assessments and decision making under climate uncertainty. Full article

The increasing global reliance on wind and solar energy underscores the critical vulnerability of renewable systems to extreme weather, which can severely disrupt power generation. Accurately modelling the complex, multivariate dependencies of weather extremes is essential for building grid resilience, yet conventional statistical models often fail to capture critical tail dependencies. This study aims to develop a robust framework using vine copulas to model the tail dependencies among key meteorological variables, extreme temperature, wind speed, and relative humidity, across the Eastern Cape province, South Africa, in order to identify optimal seasons for renewable energy production. We first clustered weather stations across the province into five distinct groups using Partitioning Around Medoids (PAM), based on geographical features (elevation, longitude, and latitude). This study explored an automatic selection of the optimal vine copula structure that adequately describes the dependence structure of the meteorological variables employed. The analysis demonstrated that R-vine copulas successfully captured the multivariate tail behaviour of temperature and relative humidity, while D-vine copulas were highly effective for wind speed. The models revealed significant tail dependencies, indicating a high potential for concurrent extreme weather events that impact energy generation. Our findings confirm that vine copulas offer a superior framework for assessing the risks associated with extreme weather to renewable energy systems. The results provide critical insights for regional energy policy and grid resilience planning, highlighting the importance of advanced risk assessment to safeguard renewable energy production against climate extremes. Full article

Accurate path planning was the prerequisite for autonomous navigation of agricultural vehicles. An Unmanned Aerial Vehicle (UAV)-based coverage path planning was developed in this research for automating guidance of agricultural vehicles and reducing the operator maneuver in the creation of navigation maps. High-resolution orthophoto maps of the field were constructed by using low-altitude UAV photogrammetry to obtain spatial information. Travel paths and working paths were automatically generated from anchor points selected by the operator under the image coordinate domain. The navigation path for unmanned agricultural vehicles was generated by Mercator projection-based conversion for the anchor pixel coordinates into latitude and longitude geographic coordinates. A Graphical User Interface (GUI) was developed for path generation, visualization, and performance evaluation, through which the proposed path planning method was implemented for autonomous agricultural vehicle navigation. Calculation accuracy tests demonstrated the mean planar coordinate error was 2.23 cm and the maximum error was 3.37 cm for path planning. Field tests showed that lateral navigation errors remained within ±5.5 cm for the unmanned high-clearance sprayer, which indicated that the developed UAV-based coverage path planning method was feasible and featured high accuracy. It provided an effective solution for achieving fully autonomous agricultural vehicle operations. Full article

Background/Objectives: Uveal melanoma (UM) is the most common primary intraocular malignancy in adults, most commonly arising in the choroid. Its development is associated with phenotypic characteristics, ultraviolet radiation, and germline or somatic genetic alterations. Despite progress in diagnostics and local therapies, UM remains characterized by high metastatic risk and poor overall prognosis. This review aimed to summarize current knowledge on epidemiology, clinical features, genetic background, prognostic factors, and therapeutic approaches in metastatic UM. Methods: A structured literature review was conducted to evaluate epidemiological trends, genetic alterations, prognostic markers, clinical presentation, and therapeutic strategies. The results of different systemic treatments were analyzed, with special attention to liver-directed interventions and emerging systemic therapies. Results: The incidence of UM in Europe increases with latitude, ranging from two per million in the southern regions to more than eight per million in the North. The median age at diagnosis is 62 years, and most cases are detected incidentally during ophthalmological examinations due to nonspecific symptoms. Some genetic alterations serve as important prognostic indicators. Local treatment consists of globe-preserving procedures, including radiation therapy, surgery, laser therapy, or enucleation, with failure rates between 6.15% and 20.8%. Up to 70% of patients develop distant metastases, predominantly in the liver. Metastatic UM (mUM) carries a poor prognosis, with overall survival ranging from 3 to 30 months. Liver-directed therapies, particularly surgical resection, provide the most favorable outcomes. Systemic therapies demonstrate limited efficacy; however, tebentafusp has shown an overall survival benefit in HLA-A*02:01 (human leukocyte antigen A*02:01)-positive patients. Conclusions: UM is a rare but aggressive malignancy with limited treatment options once metastatic. Liver-directed strategies remain the mainstay of management, while novel systemic approaches, including tebentafusp, represent promising advances. Further research is required to improve survival and expand therapeutic opportunities. Full article

Soil amendments are widely applied to improve soil fertility and structure, yet their performance in cold regions is constrained by low accumulated temperatures, frequent freeze–thaw (FT) cycles, and permafrost sensitivity. In this review, ‘cold regions’ refers to high-latitude and high-altitude areas characterized by long winters and seasonally frozen soils and/or permafrost. We screened the peer-reviewed literature using keyword-based searches supplemented by backward/forward citation tracking; studies were included when they assessed amendment treatments in cold region soils and reported measurable changes in physical, chemical, biological, or environmental indicators. Across organic, inorganic, biological, synthetic, and composite amendments, the most consistent benefits are improved aggregation and nutrient retention, stronger pH buffering, and the reduced mobility of potentially toxic elements. However, effectiveness is often site-specific and may be short-lived, and unintended risks—including greenhouse gas emissions, contaminant accumulation, and thermal disturbances—can offset gains. Cold-specific constraints are dominated by limited thermal regimes, FT disturbance, and the trade-off between surface warming for production and permafrost protection. We therefore propose integrated countermeasures: prescription-based amendment portfolios tailored to soils and seasons; the prioritization and screening of local resources; coupling with engineering and land surface strategies; a minimal cold region MRV loop; and the explicit balancing of agronomic benefits with environmental safeguards. These insights provide actionable pathways for sustainable agriculture and ecological restoration in cold regions under climate change. Full article

Atopic dermatitis (AD) is a chronic inflammatory skin disease with early-age onset. While vitamin D (VitD) has been associated with AD alleviation, geographical factors should be considered as VitD synthesis depends on sunlight exposure and dietary intake. We conducted a mapping review to identify geography-related evidence gaps in interventional and observational studies on the VitD-AD inverse association. We analyzed latitude and the Human Development Index (HDI) as background geographical factors. The review identified 38 studies (17 interventional, 21 observational), of which 26 confirmed the inverse VitD-AD association. Of all reviewed studies, 73% were from latitudes above 35° N, and 70.3% were from developed countries. The median latitude and HDI were 37.5° N and 0.915, respectively. Conversely, only 5.4% of studies were from Africa and 8.1% from Latin America. Studies that did not confirm the inverse VitD-AD association tended to be concentrated in developed countries at higher latitudes (median latitude 42.4° N, median HDI 0.937). Only 8.1% of all studies were from low-latitude developed countries, and among interventional studies this share was even lower (6.3%). In addition, 52.6% of studies lacked data on baseline VitD variability and 13.2% had no baseline VitD data at all. More thorough data reporting and additional clinical studies from countries that do not follow the high latitude/high HDI overlap pattern would facilitate future meta-analyses aimed at clarifying the role of VitD in AD treatment. Full article

The probability that female bagworms (Lepidoptera: Psychidae) are in mating time-in (live pheromone calling) was recorded in three bagworm species: Oiketicus kirbyi in a Costa Rican oil palm plantation in 1993–1994; Metisa plana in Malaysian oil palm plantations during five consecutive generations of bagworms in 1996; and Thyridopteryx ephemeraeformis on ornamental trees in the Midwest United States. Because females entirely reproduce within their bag (mate attraction, copulation, and oviposition), it is possible to assess the mating success of time-out females (dead individuals from an ongoing generation that either mated or died as a lifelong virgin) and incidence of calling females that may or may not mate before death. Synchronous larval development and discrete (non-overlapping) generations imply a declining proportion of live calling females over time in all three bagworm species: ‘young’ calling females prevail in the early season as opposed to a majority of time-out (post-reproductive) females in the late season. Calling females are long-lived relative to males (one-day lifespan) and thus expected to mate as adults when abundance of males is high and/or female longevity exceeds three days. A low mating success of calling females is associated with extreme protogyny (early season male shortage; O. kirbyi in 1994) or late adult emergence in populations at the edge of the distribution range (T. ephemeraeformis at latitudes > 41° N in 2019). Full article

Baroclinic wave resonance, particularly Rossby waves, has attracted great interest in ocean and atmospheric physics since the 1970s. Research on Rossby wave resonance covers a wide variety of phenomena that can be unified when focusing on quasi-stationary Rossby waves traveling at the interface of two stratified fluids. This assumes a clear differentiation of the pycnocline, where the density varies strongly vertically. In the atmosphere, such stationary Rossby waves are observable at the tropopause, at the interface between the polar jet and the ascending air column at the meeting of the polar and Ferrel cell circulation, or between the subtropical jet and the descending air column at the meeting of the Ferrel and Hadley cell circulation. The movement of these air columns varies according to the declination of the sun. In oceans, quasi-stationary Rossby waves are observable in the tropics, at mid-latitudes, and around the subtropical gyres (i.e., the gyral Rossby waves GRWs) due to the buoyant properties of warm waters originating from tropical oceans, transported to high latitudes by western boundary currents. The thermocline oscillation results from solar irradiance variations induced by the sun’s declination, as well as solar and orbital cycles. It is governed by the forced, linear, inviscid shallow water equations on the β-plane (or β-cone for GRWs), namely the momentum, continuity, and potential vorticity equations. The coupling of multi-frequency wave systems occurs in exchange zones. The quasi-stationary Rossby waves and the associated zonal/polar and meridional/radial geostrophic currents modify the geostrophy of the basin. Here, it is shown that the ubiquity of resonant forcing in (sub)harmonic modes of Rossby waves in stratified media results from two properties: (1) the natural period of Rossby wave systems tunes to the forcing period, (2) the restoring forces between the different multi-frequency Rossby waves assimilated to inertial Caldirola–Kanai (CK) oscillators are all the stronger when the imbalance between the Coriolis force and the horizontal pressure gradients in the exchange zones is significant. According to the CK equations, this resonance mode ensures the sustainability of the wave systems despite the variability of the forcing periods. The resonant forcing of quasi-stationary Rossby waves is at the origin of climate variations, as well-known as El Niño, glacial–interglacial cycles or extreme events generated by cold drops or, conversely, heat waves. This approach attempts to provide some new avenues for addressing climate and weather issues. Full article

The thermosphere serves as a pivotal region for Sun–Earth interactions, and thermospheric winds are of great scientific importance for deepening insights into atmospheric dynamics, climate formation mechanisms, and space environment evolution. This study designed and developed a Ground-based Doppler Asymmetric Spatial Heterodyne Interferometer (GDASHI). Targeting the nightglow of the oxygen atomic red line (OI 630.0 nm), this instrument enables high-precision observation of thermospheric winds. The GDASHI was deployed at Gemini Astronomical Manor (26.7°N, 100.0°E), and has obtained one year of nighttime meridional and zonal wind data. To verify the reliability of GDASHI-derived winds, a collocated observation comparison was performed against the Dual-Channel Optical Interferometer stationed at Binchuan Station (25.6°N, 100.6°E), Yunnan. The winds of the two instruments are basically consistent in both their diurnal variation trends and amplitudes. Further Deming regression and correlation analysis were conducted for the two datasets, with the meridional and zonal winds yielding fitting slopes of 0.808 and 0.875 and correlation coefficients of 0.754 and 0.771, respectively. An uncertainty analysis of the inter-instrument comparison was also carried out, incorporating instrumental measurement uncertainties, instrumental parameter errors, and small-scale perturbations induced by observational site differences; the synthesized total uncertainties of zonal and meridional winds are determined to be 20.24 m/s and 20.77 m/s, respectively. This study not only verifies the feasibility and reliability of GDASHI for ground-based thermospheric wind detection but also provides critical observational support for analyzing the spatiotemporal variation characteristics of mid-low latitude thermospheric wind fields and exploring their underlying physical mechanisms. Full article

Improving the accuracy of climate and long-range meteorological forecasts is an important objective for many economic sectors: agriculture, energy and utilities, transportation and logistics, construction, disaster risk management, insurance and finance, retail, tourism and leisure. Traditional physical models face limitations at ultra-long lead times, which motivates the development of empirical–statistical approaches, including those leveraging deep learning techniques. In this study, using ERA5 reanalysis data and archives of major climate indices for the period 1950–2024, we examine statistical relationships between climate indices associated with large-scale atmospheric and oceanic patterns in the Northern Hemisphere and surface air temperature anomalies in selected mid- and high-latitude regions. The aim is to assess the predictive skill of these indices for seasonal temperature anomalies within empirical forecasting frameworks. To this end, we employ cross-correlation and cross-spectral analyses, as well as regression modeling. Our findings indicate that the choice of the most informative predictors strongly depends on the target region and season. Among the major indices, AMO and EA/WR emerge as the most informative for forecasting purposes. The Niño 4 and IOD indices can be considered useful predictors for the Eastern Arctic. Notably, the strongest correlations between the AMO, EA/WR, Niño 4, and IOD indices and surface air temperature occur at one- to two-year lags. To illustrate the predictive potential of the four selected indices, several multiple regression models were developed. The results obtained from these models confirm that the chosen set of indices effectively captures the main sources of variability relevant to seasonal and interannual temperature prediction across the analyzed regions. In particular, approximately 64% of the forecasts have errors less than 0.674 times the standard deviation. Full article

NavIC and GPS are satellite-based navigation systems developed by India and the United States, respectively, and are widely used for ionospheric and space weather studies. This paper presents a comparative analysis of NavIC- and GPS-derived total electron content (TEC) during a High-Intensity Long-Duration Continuous AE Activity (HILDCAA) event that occurred from 17 to 21 August 2017. The analysis covers the five days of the event, along with three days before and after, using observations from a single low-latitude station over the Indian region. NavIC performance is evaluated by comparing vertical TEC (vTEC) derived from dual-frequency pseudorange measurements with co-located GPS-derived vTEC. The results show a strong linear correspondence between the two datasets, with Pearson correlation coefficients exceeding ∼0.97 throughout the event interval. Such high correlation is physically expected, as the dominant contribution to TEC arises from the common vertical ionospheric column sampled by both systems. Nevertheless, the close agreement observed under sustained geomagnetic disturbance conditions demonstrates that NavIC is capable of consistently capturing ionospheric TEC variability during this specific HILDCAA event. Full article

This study investigates peak daylight exposure in zenithally lit museum rooms at 51° latitude through an experimental campaign using a 1:20 physical mock-up of a 12 × 12 × 6 m exhibition gallery space. Nine configurations of shading and light-transmitting elements (CSaLTE) were tested under real clear-sky conditions between June and October. To ensure a valid comparative analysis, indoor vertical illuminance (E_v) was measured at 15 min intervals and subsequently interpolated and normalised to a unified equinox-day solar geometry (06:00–18:00). This hybrid empirical-computational methodology allows for a direct performance comparison across different geometric arrangements regardless of their specific measurement dates. The results demonstrate that while traditional annual metrics are the standard, short-term illuminance peaks pose a severe and underexplored threat to conservation safety. Even the most light-attenuating diffusing-roof configurations produced short-term illuminance peaks and cumulative clear-sky exposures that are comparable in magnitude to commonly cited annual limits for highly light-sensitive materials, with several configurations recording extreme spikes surpassing the sensor’s 20,000 lx saturation limit. Stable, low-illuminance distributions were observed only in selected diffusing-roof arrangements (M05–M07), whereas direct-glazing systems (M01–M04) produced unsafe exposure patterns with high temporal variability and poor visual adaptation conditions. The study concludes that passive roof geometries alone are insufficient to ensure conservation-level safety without additional active filtering or adaptive control strategies, providing an experimentally grounded framework for designing zenithal daylighting systems in museum environments. The results are intended for relative peak-risk comparison under controlled clear-sky conditions rather than direct generalisation to whole-room annual conservation safety. Full article

Gravity waves (GWs) are an important dynamic process in the planetary atmosphere. They are typically excited by convection, topography, or other sources from the lower atmosphere and propagate upwards. The GWs have a significant effect on the global atmospheric circulation on Mars. However, the lack of high-resolution data from previous observations has resulted in an insufficient understanding of GWs in the Martian atmosphere, particularly in terms of its global distribution and long-term evolution characteristics at different altitudes. Based on multiple years of Mars Climate Sounder (MCS) limb observations on board the Mars Reconnaissance Orbiter (MRO), we conducted a detailed study of the global distribution, seasonal and interannual variations in Martian atmospheric GWs with vertical wavelengths ranging from 9 to 15 km at three different altitude ranges, i.e., the low-altitude range of 200–20 Pa (Lp, ~10–30 km), the mid-altitude range of 20–2 Pa (Mp, ~30–50 km), and the high-altitude range of 2–0.2 Pa (Hp, ~50–70 km). The results indicate complex regional and north–south differences, as well as night–day variations, in the spatial distribution of GWs. Particularly, a three-wave structure of the GW activity is observed over mountainous regions in the mid-to-low latitudes of the Northern Hemisphere. The peak longitude range of this structure closely matches the mountainous terrain. In addition, our results reveal the presence of bands of GW aggregations in the mid- to-high latitudes of the Northern Hemisphere in the Mp and Hp layers, which may be caused by the instability of the polar jet. There are also obvious seasonal and interannual variations in GW activities, which are related to topography, polar jets, and large dust storms. The interannual variations in GWs imply that, in addition to the well-known large seasonal dust storms, complex interannual variations in atmospheric activity over the polar jets and in the complex topography at mid-to-low latitudes on Mars may also exist, which deserve further studies in the future. Full article