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6 Results Found

  • Article
  • Open Access
5 Citations
3,808 Views
12 Pages

31 March 2020

Background: Ginsenosides, triterpene saponins of Panax species, are considered the main active ingredients responsible for various pharmacological activities. Herein, a new protopanaxatriol-type ginsenoside called “ginsenoside MT1” is des...

  • Article
  • Open Access
4 Citations
3,132 Views
16 Pages

Synthesis, Anti-Inflammatory Activities, and Molecular Docking Study of Novel Pyxinol Derivatives as Inhibitors of NF-κB Activation

  • Shuai Tan,
  • Zongji Zou,
  • Xuwen Luan,
  • Cheng Chen,
  • Shuang Li,
  • Zhen Zhang,
  • Mengran Quan,
  • Xiang Li,
  • Wei Zhu and
  • Gangqiang Yang

10 April 2024

Pyxinol, an active metabolite of ginsenosides in human hepatocytes, exhibits various pharmacological activities. Here, a series of C-3 modified pyxinol derivatives was designed and virtually screened by molecular docking with the key inflammation-rel...

  • Article
  • Open Access
19 Citations
7,156 Views
18 Pages

The Multi-Template Molecularly Imprinted Polymer Based on SBA-15 for Selective Separation and Determination of Panax notoginseng Saponins Simultaneously in Biological Samples

  • Chenghong Sun,
  • Jinhua Wang,
  • Jiaojiao Huang,
  • Dandan Yao,
  • Chong-Zhi Wang,
  • Lei Zhang,
  • Shuying Hou,
  • Lina Chen and
  • Chun-Su Yuan

28 November 2017

The feasible, reliable and selective multi-template molecularly imprinted polymers (MT-MIPs) based on SBA-15 (SBA-15@MT-MIPs) for the selective separation and determination of the trace level of ginsenoside Rb1 (Rb1), ginsenoside Rg1 (Rg1) and notogi...

  • Article
  • Open Access
46 Citations
5,164 Views
15 Pages

3 December 2019

This study aimed to evaluate whether ginsenosides Rb1 (20-S-protopanaxadiol aglycon) and Rg1 (20-S-protopanaxatriol aglycon) have mitochondrial protective effects against oxygen-glucose deprivation/reoxygenation (OGD/R)-induced injury in primary mous...

  • Article
  • Open Access
41 Citations
4,523 Views
16 Pages

28 September 2021

Breast cancer (BC) a very common cancer in women worldwide. Triple negative breast cancer (TNBC) has been shown to have a poor prognosis with a high level of tumor metastatic spread. Here, the inhibitory effects of ginsenoside-Rh1 (Rh1) on BC metasta...

  • Article
  • Open Access
48 Citations
5,699 Views
19 Pages

5 October 2019

(1) Aims: The present study aimed to observe the effects of Ginsenoside Rb1 on high glucose-induced endothelial damage in rat retinal capillary endothelial cells (RCECs) and to investigate the underlying mechanism. (2) Methods: Cultured RCECs were tr...