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  • Article
  • Open Access
2 Citations
2,691 Views
15 Pages

Preparation, Purification, Characterization and Antioxidant Activity of Rice Bran Fermentation Broth with Hypsizigus marmoreus

  • Yanping Chi,
  • Lining Kang,
  • Xiangying Liu,
  • Hongrui Sun,
  • Yue Meng,
  • Jialin Zhang,
  • You Kang and
  • Yonggang Dai

The main purpose of this study was to investigate the composition, characterization and antioxidant activity of rice bran fermentation broth, and provide a new way for high-value utilization of rice bran. Firstly, we fermented rice bran with Hypsizig...

  • Article
  • Open Access
2 Citations
2,807 Views
15 Pages

21 February 2025

In this work, Staphylococcus epidermidis (S. epidermidis) fermentation broth with inhibitory effects on the growth of Propionibacterium acnes (P. acnes) and inflammation caused by P. acnes. was obtained. Three kinds of S. epidermidis fermentation bro...

  • Article
  • Open Access
2,857 Views
12 Pages

Conversion of Enantiomers during the Separation of Acetoin from Fermentation Broth

  • Jiaxiang Zhang,
  • Zhihao Fu,
  • Xiangying Zhao,
  • Mingjing Yao,
  • Yuchen Li,
  • Liping Liu,
  • Jianjun Liu and
  • Yanjun Tian

Acetoin (AC) is an important platform compound with two enantiomers (R)-AC and (S)-AC. Due to its unique spatial structure, optically pure AC has particularly high application in asymmetric synthesis. Highly optically pure AC could be produced from g...

  • Article
  • Open Access
4 Citations
2,880 Views
15 Pages

Lactic acid (LA) is an important chemical material facing rapid demand in recent years. The oriented fermentation of kitchen waste is a promising route for economic LA production. However, the refinement of LA from fermentation broth is a spiny issue...

  • Article
  • Open Access
6 Citations
3,753 Views
18 Pages

Protective Mechanism of Rosa roxburghii Tratt Fermentation Broth against Ultraviolet-A-Induced Photoaging of Human Embryonic Skin Fibroblasts

  • Minglu Yuan,
  • Hao Fu,
  • Qiuting Mo,
  • Shiwei Wang,
  • Changtao Wang,
  • Dongdong Wang,
  • Jiachan Zhang and
  • Meng Li

This study takes the fruit of Rosa roxburghii Tratt (RRT) as a fermentation substrate and carries out a quantitative visual analysis of the domestic and foreign literature on screenings of five different lactic acid bacteria to obtain a fermentation...

  • Article
  • Open Access
217 Views
24 Pages

Optimization of Liquid Culture of Extracellular Flavonoids of Sanghuangporus and Evaluation of Antioxidant Activity of Fermentation Broth

  • Yingbai Wang,
  • Junliang Chen,
  • Yingkun Yang,
  • Zhaojuan Zhang,
  • Weiming Cai,
  • Xingru Yan,
  • Yu Peng,
  • Yu Li and
  • Pu Liu

28 January 2026

Species of Sanghuangporus produce abundant bioactive compounds, including flavonoids, polysaccharides, and triterpenoids, among which flavonoids exhibit prominent antioxidant activity and great development potential. Taking the peak extracellular fla...

  • Article
  • Open Access
8 Citations
3,861 Views
11 Pages

19 June 2020

Potato starch was esterified with carboxylic acids contained in the fermentation broth from Yarrowia lipolitica yeast production. Various acid concentrations and various roasting temperatures were used to determine effects of process conditions on es...

  • Article
  • Open Access
15 Citations
4,021 Views
17 Pages

When the toxic red tide alga Gymnodinium catenatum H.W. Graham accumulates in sediment through sexual reproduction, it provides the provenance of a periodic outbreak of red tide, a potential threat to the marine environment. In our study, the floccul...

  • Article
  • Open Access
12 Citations
3,265 Views
14 Pages

17 September 2022

Pear fruits have been reported to contain abundant bioactive compounds and exhibit antidiabetic activity. In this study, Pingguoli pear (Pyrus pyrifolia cv.‘Pingguoli’) fermentation broth was sequentially extracted by five solvents with i...

  • Article
  • Open Access
14 Citations
4,930 Views
11 Pages

Postharvest Application of Bacillus amyloliquefaciens PMB04 Fermentation Broth Reduces Anthracnose Occurrence in Mango Fruit

  • Yu-Shen Liang,
  • Ju-Yin Fu,
  • Szu-Han Chao,
  • Yuh Tzean,
  • Chia-Yu Hsiao,
  • Yung-Yu Yang,
  • Yu-Kuo Chen and
  • Yi-Hsien Lin

9 October 2022

Anthracnose is a destructive postharvest disease of mango fruit, especially after ripening. The application of antagonistic Bacillus spp. strains is one of many promising control strategies. B. amyloliquefaciens (PMB04) exhibits strong antagonistic a...

  • Article
  • Open Access
2 Citations
3,504 Views
16 Pages

Aspergillus niger Fermentation Broth Promotes Maize Germination and Alleviates Low Phosphorus Stress

  • Maoxian Tian,
  • Changhui Zhang,
  • Zhi Zhang,
  • Tao Jiang,
  • Xiaolan Hu,
  • Hongbo Qiu and
  • Zhu Li

Aspergillus niger is a type of soil fungus with the ability to dissolve insoluble phosphate and secrete organic metabolites such as citric acid. However, whether cell-free Aspergillus niger fermentation broth (AFB) promotes maize growth and alleviate...

  • Review
  • Open Access
66 Citations
21,261 Views
14 Pages

Fermented Broth in Tyrosinase- and Melanogenesis Inhibition

  • Chin-Feng Chan,
  • Ching-Cheng Huang,
  • Ming-Yuan Lee and
  • Yung-Sheng Lin

26 August 2014

Fermented broth has a long history of applications in the food, pharmaceutical and cosmetic industries. Recently, the use of fermented broth in skin care products is in ascendance. This review investigates the efficacy of fermented broth in inhibitin...

  • Article
  • Open Access
4 Citations
4,134 Views
15 Pages

16 June 2022

For pollution control and waste utilization, a promising future direction is to obtain high-value carbon sources from organic waste. In this experiment, swine manure was efficiently converted into high concentration volatile fatty acids through conti...

  • Article
  • Open Access
2 Citations
4,105 Views
16 Pages

Dual Mechanisms of Action: Anti-Candida and Anti-Inflammatory Potential of Lactobacillus Fermentation Broth in Treating Vulvovaginal Candidiasis

  • Huann-Cheng Horng,
  • Jin-Wei Xu,
  • Yi-Shan Kuo,
  • Yu-Sin Chen,
  • Yu-Hsuan Chiu,
  • Kuan-Hao Tsui and
  • Yu-Tang Tung

30 December 2024

Vulvovaginal candidiasis (VVC), a condition predominantly caused by Candida albicans, affects millions of women worldwide, prompting the need for alternative treatments due to the side effects and increasing resistance associated with conventional im...

  • Article
  • Open Access
1,151 Views
17 Pages

Excessive application of phosphate fertilizers exacerbates water pollution, while the low phosphorus availability in acidic soils results in diminished phosphorus utilization efficiency of crops. This study conducted a maize pot experiment to investi...

  • Article
  • Open Access
1 Citations
1,771 Views
14 Pages

8 September 2023

Overnutrition with a high-fat or high-sugar diet is widely considered to be the risk factor for various metabolic, chronic, or malignant diseases that are accompanied by alterations in gut microbiota, metabolites, and downstream pathways. In this stu...

  • Article
  • Open Access
3 Citations
1,197 Views
23 Pages

Fouling Mechanisms in the Clarification of 1,3-Propanediol Fermentation Broths by Membrane Processes

  • Hong Chen,
  • Fu Yang,
  • Qianyu Wang,
  • Tianyu Zheng,
  • Rongqing Zhou,
  • Chongde Wu and
  • Yao Jin

12 September 2025

Membrane separation is an effective means of separating 1,3-propanediol (1,3-PD) from fermentation broth. However, systematic studies on membrane fouling behavior during this process are still limited. Therefore, this study systematically analyzed th...

  • Article
  • Open Access
20 Citations
5,789 Views
23 Pages

This paper reports the study of the cross-flow microfiltration (MF) of glycerol fermentation broths with Citrobacter freundii bacteria. A single channel tubular ceramic membrane with a nominal pore size of 0.14 µm was used. It has been demonstr...

  • Article
  • Open Access
8 Citations
4,683 Views
15 Pages

27 February 2023

Fermentation broth is plentiful with lactic acid, an important chemical applied in many fields, such as food processing, the chemical industry, and cosmetics. However, the purification of the lactic acid from the broth is still troublesome, when cons...

  • Article
  • Open Access
21 Citations
3,992 Views
16 Pages

Management of Dark Fermentation Broth via Bio Refining and Photo Fermentation

  • Karolina Kucharska,
  • Patrycja Makoś-Chełstowska,
  • Edyta Słupek and
  • Jacek Gębicki

1 October 2021

Lignocellulose and starch-based raw materials are often applied in the investigations regarding biohydrogen generation using dark fermentation. Management of the arising post-fermentation broth becomes a problem. The Authors proposed sequential proce...

  • Article
  • Open Access
6 Citations
2,853 Views
13 Pages

Studies on Reactive Extraction of Itaconic Acid from Fermentation Broths

  • Alexandra Cristina Blaga,
  • Lenuta Kloetzer,
  • Dan Cascaval,
  • Anca-Irina Galaction and
  • Alexandra Tucaliuc

3 April 2024

Itaconic acid is a high-value organic acid that serves as a platform molecule in different industries. This research focuses on the separation of itaconic acid using reactive extraction as a sustainable and efficient method for acid recovery from fer...

  • Article
  • Open Access
20 Citations
5,600 Views
24 Pages

14 December 2022

The potential for nanofiltration (NF) in removing both relatively low molecular weight (MW) organic species and charged solutes from complex media is noteworthy. The main aim of the current work was to improve understanding of the separation mechanis...

  • Article
  • Open Access
18 Citations
9,238 Views
14 Pages

Degradation Kinetics of Clavulanic Acid in Fermentation Broths at Low Temperatures

  • David Gómez-Ríos,
  • Howard Ramírez-Malule,
  • Peter Neubauer,
  • Stefan Junne and
  • Rigoberto Ríos-Estepa

Clavulanic acid (CA) is a β-lactam antibiotic inhibitor of β-lactamase enzymes, which confers resistance to bacteria against several antibiotics. CA is produced in submerged cultures by the filamentous Gram-positive bacterium Streptomyces c...

  • Article
  • Open Access
31 Citations
5,322 Views
26 Pages

In recent years, microfiltration (MF) has gained great interest as an excellent technique for clarification of biological suspensions. This paper addresses a direct comparison of efficiency, performance and susceptibility to cleaning of the ceramic a...

  • Article
  • Open Access
14 Citations
4,891 Views
16 Pages

3 October 2022

Recently, there has been a special research focus on the bioconversion of glycerol to 1,3-propanediol (1,3-PD) due to its significance in the chemical industry. However, the treatment and separation of fermentation broths is a great challenge. Curren...

  • Article
  • Open Access
16 Citations
5,495 Views
15 Pages

12 September 2023

Treatment for sepsis and its complications in the clinic is primarily in the forms of antibiotics, anti-inflammatory agents, and antioxidant drugs. Kombucha, a traditional fermented beverage rich in tea polyphenols and organic acids, offers several b...

  • Article
  • Open Access
11 Citations
6,252 Views
29 Pages

Investigating a Stirred Bioreactor: Impact of Evolving Fermentation Broth Pseudoplastic Rheology on Mixing Mechanisms

  • M. Constanza Sadino-Riquelme,
  • José Rivas,
  • David Jeison,
  • Andrés Donoso-Bravo and
  • Robert E. Hayes

The culture medium in many fermentations is a non-Newtonian fluid. In bacterial alginate batch production, the broth becomes more pseudoplastic as the alginate concentration increases, which impairs the mixing process. This work characterizes the eff...

  • Article
  • Open Access
21 Citations
3,761 Views
22 Pages

Kidney Bean Fermented Broth Alleviates Hyperlipidemic by Regulating Serum Metabolites and Gut Microbiota Composition

  • Weiqiao Pang,
  • Di Wang,
  • Zhaohang Zuo,
  • Ying Wang,
  • Wei Sun,
  • Naidan Zhang and
  • Dongjie Zhang

5 August 2022

Hyperlipidemia with fat accumulation and weight gain causes metabolic diseases and endangers human body health easily which is accompanied by metabolic abnormalities and intestinal flora disorders. In this study, the kidney bean fermented broth (KBF)...

  • Article
  • Open Access
6 Citations
3,225 Views
15 Pages

9 March 2023

Recent findings regarding nanofiltration (NF) have led to indications that it can be successfully used for separation of various biological solutions. As a novelty, this paper is the first to investigate the impact of the feed pretreatment process on...

  • Article
  • Open Access
41 Citations
6,321 Views
6 Pages

1 March 2013

The new compound Z-4-2 was isolated from the fermentation broth of Streptomyces djakartensis NW35, together with the known compound N-acetyltryptamine (Z-9-2) by bioassay-guided fractionation. Its chemical structure was elucidated as (E)-2-methoxy-1,...

  • Article
  • Open Access
52 Citations
4,920 Views
12 Pages

Anticancer Action and Mechanism of Ergosterol Peroxide from Paecilomyces cicadae Fermentation Broth

  • Linfu He,
  • Wenjing Shi,
  • Xiaocui Liu,
  • Xiaohuan Zhao and
  • Zhicai Zhang

7 December 2018

Isaria cicadae, a medicinal food fungus, is a fruit from Paecilomyces cicadae. In this study, we purified ergosterol peroxide (EP) from the fermentation broth of P. cicadae and investigated its effects on renal cell carcinoma (RCC) cells, in vitro. E...

  • Article
  • Open Access
495 Views
18 Pages

Applicability Assessment of a Microbial Proteolytic Fermentation Broth to Leather Processing and Protein Stain Removal

  • Manuela Lageiro,
  • Maria João Moura,
  • Fernanda Simões,
  • Nuno Alvarenga and
  • Alberto Reis

29 January 2026

Microbial proteases are fundamental towards the eco-sustainability of proteolysis at the industrial scale. A proteolytic broth was obtained from a bioreactor fermentation of a proteolytic Bacillus strain isolated from an industrial alkaline bath. Bro...

  • Article
  • Open Access
1 Citations
719 Views
22 Pages

In the development of high-temperature and high-salinity oil fields, biopolymer scleroglucan flooding technology faces significant challenges. Traditional scleroglucan products exhibit poor injectability and high extraction costs. This study investig...

  • Feature Paper
  • Article
  • Open Access
6 Citations
3,344 Views
15 Pages

Valorization of Spent Sugarcane Fermentation Broth as a Source of Phenolic Compounds

  • Carla Maria Oliveira,
  • Bruno Horta,
  • Tânia Leal,
  • Manuela Pintado and
  • Catarina S. S. Oliveira

8 July 2022

A methodology based on a solid phase extraction (SPE) was optimized for the recovery of phenolic compounds from the spent fermentation broth generated from Biofene® (trans-β-farnesene) production. For this purpose, two resins (XAD-2 and HP-2...

  • Article
  • Open Access
6 Citations
3,961 Views
16 Pages

30 December 2022

This study researches the active ingredients in the fermented and aqueous extracts of three types of Coix seed. The results show that the active contents of total sugars, total phenols and total proteins of Coix seed fermented with Lactobacillus reut...

  • Article
  • Open Access
3 Citations
2,569 Views
18 Pages

Astragali Radix, a traditional Chinese herbal medicine widely used for its medicinal properties, is known to be rich in active components that possess various pharmacological effects. However, the effectiveness of microbial fermentation in enhancing...

  • Article
  • Open Access
9 Citations
8,343 Views
11 Pages

A large amount of foam is generated in the production of microbial oil and exopolysaccharide (EPS) by Sporidiobolus pararoseus JD-2, which causes low efficiency in fermentation. In this study, we aimed to reduce the negative effects of foams on the c...

  • Article
  • Open Access
1 Citations
1,867 Views
10 Pages

About 95% of global hydrogen production is made by fossil fuels using different technologies which are all characterized by high energy consumption and high carbon emissions. Alternatively, more sustainable production methods, such as biological ferm...

  • Article
  • Open Access
5 Citations
3,839 Views
12 Pages

Stability of Filled PDMS Pervaporation Membranes in Bio-Ethanol Recovery from a Real Fermentation Broth

  • Cédric Van Goethem,
  • Parimal V. Naik,
  • Miet Van de Velde,
  • Jim Van Durme,
  • Alex Verplaetse and
  • Ivo F. J. Vankelecom

27 October 2023

Mixed matrix membranes (MMMs) have shown great potential in pervaporation (PV). As for many novel membrane materials however, lab-scale testing often involves synthetic feed solutions composed of mixed pure components, overlooking the possibly comple...

  • Article
  • Open Access
18 Citations
7,648 Views
7 Pages

23 February 2011

Dihydroberkleasmin A (1), a new ester-substituted sesquiterpenoid related to the eremophilane class, together with the known compound berkleasmin C (2), were isolated from the fermentation broth of the plant endophytic fungus Pestalotiopsis photiniae...

  • Article
  • Open Access
8 Citations
3,777 Views
18 Pages

Variables and Mechanisms Affecting Electro-Membrane Extraction of Bio-Succinic Acid from Fermentation Broth

  • Alina Anamaria Malanca,
  • Enrico Mancini,
  • Mohamed Yusuf,
  • Gabriel Kjær Khensir,
  • Seyed Soheil Mansouri,
  • Ioannis V. Skiadas,
  • Hariklia N. Gavala and
  • Manuel Pinelo

The production of succinic acid from fermentation is a promising approach for obtaining building-block chemicals from renewable sources. However, the limited bio-succinic yield from fermentation and the complexity of purification has been making the...

  • Article
  • Open Access
4 Citations
2,244 Views
13 Pages

23 December 2024

Nitrite hazard is an important food safety issue in the production process of Chinese Northeastern sauerkraut, but this nitrite can be eliminated through microbial enzymatic degradation and acidic degradation as fermentation progresses. Therefore, an...

  • Article
  • Open Access
3,546 Views
13 Pages

Isolation and Purification of a Hydrophobic Non-Ribosomal Peptide from an Escherichia coli Fermentation Broth

  • Arne Michael Oestreich,
  • Sebastian Reinhardt,
  • Doreen Gerlach,
  • Rong Fan and
  • Peter Czermak

Non-ribosomal peptide synthases (NRPSs) generate versatile bioactive peptides by incorporating non-proteinogenic amino acids and catalyzing diverse modifications. Here, we developed an efficient downstream process for the capture, intermediate purifi...

  • Communication
  • Open Access
14 Citations
3,603 Views
10 Pages

DPPH Radical Scavenging Activity of New Phenolics from the Fermentation Broth of Mushroom Morehella importuna

  • Feifei Wang,
  • Jie Tan,
  • Ruixiang Jiang,
  • Feifei Li,
  • Renqing Zheng,
  • Linjun Yu,
  • Lianzhong Luo and
  • Yongbiao Zheng

14 June 2023

In recent years, wild morel mushroom species have begun to be widely cultivated in China due to their high edible and medicinal values. To parse the medicinal ingredients, we employed the technique of liquid-submerged fermentation to investigate the...

  • Article
  • Open Access
8 Citations
4,523 Views
19 Pages

Influence of Ceramic Membrane Surface Characteristics on the Flux Behavior of a Complex Fermentation Broth

  • Nicolas A. P. Maguire,
  • Mehrdad Ebrahimi,
  • Rong Fan,
  • Sabine Gießelmann,
  • Frank Ehlen,
  • Steffen Schütz and
  • Peter Czermak

The valorization of agro-industrial residues using yeasts as biocatalysts requires efficient methods for biomass separation. Filtration with ceramic membranes is suitable for this task, however, the challenge of flux decline and the unavoidable clean...

  • Article
  • Open Access
11 Citations
3,096 Views
23 Pages

Fouling of Polyalkylmethylsiloxane Composite Membranes during Pervaporation Separation of ABE-Fermentation Mixtures

  • Tatyana N. Rokhmanka,
  • Evgenia A. Grushevenko,
  • Olga V. Arapova,
  • Galina N. Bondarenko,
  • George S. Golubev,
  • Ilya L. Borisov and
  • Alexey V. Volkov

16 March 2023

Production of bio-alcohols is one of the approaches used in the development of alternative energy. Pervaporation is a promising option for the separation of bio-alcohols from the fermentation mixture. A serious problem in the process of continuous ex...

  • Article
  • Open Access
1 Citations
1,810 Views
13 Pages

14 February 2025

γ-aminobutyric acid, a critical neurotransmitter, is experiencing an increasing demand in the medical and health fields. Conventional processes for γ-aminobutyric acid purification from fermentation broth encounter significant challenges,...

  • Article
  • Open Access
4 Citations
2,964 Views
13 Pages

Inhibition of Potato Fusarium Wilt by Bacillus subtilis ZWZ-19 and Trichoderma asperellum PT-29: A Comparative Analysis of Non-Targeted Metabolomics

  • Jianxiu Hao,
  • Zhen Wang,
  • Yuanzheng Zhao,
  • Shujie Feng,
  • Zining Cui,
  • Yinqiang Zhang,
  • Dong Wang and
  • Hongyou Zhou

22 March 2024

Potato Fusarium Wilt is a soil-borne fungal disease that can seriously harm potatoes throughout their growth period and occurs at different degrees in major potato-producing areas in China. To reduce the use of chemical agents and improve the effect...

  • Article
  • Open Access
1 Citations
1,680 Views
20 Pages

Oyster Fermentation Broth Alleviated Tripterygium-Glycosides-Induced Reproductive Damage in Male Rats

  • Jiajia Yin,
  • Hongguang Zhu,
  • Yu Tian,
  • Tengyu Ma,
  • Wenjing Yan and
  • Haixin Sun

29 August 2025

In this study, oyster fermentation broth (OFB) was prepared by fermenting oysters with yeast, and its effects on oxidative stress and reproductive damage induced by tripterygium glycosides (TG) in male rats were investigated. Component analysis revea...

  • Article
  • Open Access
1 Citations
1,069 Views
16 Pages

12 June 2025

The focus of this work was to perform a preliminary study on the suitability of commercially available nanofiltration (NF) and reverse osmosis (RO) membranes for the separation of 1,3-propanediol (1,3-PD) post-fermentation solutions. The experiments...

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