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Keywords = cushioning properties

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18 pages, 2023 KB  
Article
Factors Affecting the Cushioning Performance of Granular Materials and the Application in AEM Signal Surveys
by Lifang Fan, Shaomin Liang, Yanpeng Liu, Guangbo Xiang, Wei Zhang and Xuexi Min
Signals 2026, 7(2), 31; https://doi.org/10.3390/signals7020031 - 2 Apr 2026
Viewed by 529
Abstract
Airborne electromagnetic (AEM) surveys map subsurface electrical structures by deploying transmitter and receiver coils on an airborne platform. However, platform-induced vibrations are transmitted to the sensors, generating strong motion-induced noise that severely degrades signal quality. To mitigate such noise, this study proposed the [...] Read more.
Airborne electromagnetic (AEM) surveys map subsurface electrical structures by deploying transmitter and receiver coils on an airborne platform. However, platform-induced vibrations are transmitted to the sensors, generating strong motion-induced noise that severely degrades signal quality. To mitigate such noise, this study proposed the use of granular materials as a cushioning medium. An impact model based on the Discrete Element Method (DEM) was developed and validated against drop-weight experiments. Both granular material properties and impactor characteristics were investigated. The study examined the cushioning effects on both the base plate and the impactor under impact loading, and the sensitivity of key parameters was evaluated. The results showed that granular properties had minimal influence on the impactor peak force. Increasing particle Young’s modulus, density, or friction coefficient led to higher peak forces on the base plate, with Young’s modulus and density having significantly stronger effects than friction coefficient. Additionally, both the impactor size and velocity correlate positively with the peak forces transmitted to the base plate and experienced by the impactor. Under thin layer conditions, the impactor force was more sensitive to impact parameters, while in thick layers it was mainly determined by particle rearrangement and energy dissipation mechanisms. These findings reveal the mechanisms governing granular cushioning and provide a theoretical basis for vibration isolation design in AEM systems to preserve high-fidelity signals. Full article
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14 pages, 3009 KB  
Article
Effects of Canine Paw Pad Morphology on Nonlinear Mechanical Behavior and Cushioning Performance
by Huaibin Miao, Long Zheng and Luquan Ren
Appl. Sci. 2026, 16(5), 2378; https://doi.org/10.3390/app16052378 - 28 Feb 2026
Viewed by 416
Abstract
The paw pad is an outstanding cushioning structure, which demonstrates nonlinear mechanical characteristics when subjected to pressure. Nonlinear mechanical characteristics are generally considered to be related to the viscoelastic properties of the material. However, the relationship between its nonlinear mechanical properties and the [...] Read more.
The paw pad is an outstanding cushioning structure, which demonstrates nonlinear mechanical characteristics when subjected to pressure. Nonlinear mechanical characteristics are generally considered to be related to the viscoelastic properties of the material. However, the relationship between its nonlinear mechanical properties and the morphological characteristics of the paw pad remains unknown. In this study, morphological data, mechanical data, and finite element simulation methods were integrated to explore how the unique shape of the paw pads enables them to exhibit excellent cushioning performance. The research findings indicate that the paw pad exhibits an irregular morphology. Nevertheless, its cross-sectional area increases in proportion to the increase in the paw pad height, presenting a linear gradient relationship (R2 = 0.99). Two comparison models with the same volume and height but different morphologies as the paw pad model, were designed for finite element simulation. The finite element static analysis shows that the influence of morphology is mainly reflected in the early deformation process, while the influence of viscoelastic material properties is reflected in the later load-bearing capacity. The finite element dynamic analysis shows that compared with the comparison models, the paw pad model has a more stable force during the impact process, without an instantaneous impact force at the initial contact moment. Moreover, the peak normal ground reaction force (GRF) component under different impact speeds is lower than that of the comparison models, demonstrating better buffering effects. The research results can provide inspiration and a biomechanical basis for the morphological design of buffering units. Full article
(This article belongs to the Section Mechanical Engineering)
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17 pages, 4719 KB  
Article
Experimental and Numerical Study on the Mechanical Properties of Alumina Ceramics Based on a Modified SHPB Setup
by Shenglin Li, Baozhen Chen, Yuanpeng Sun, Yan Wang, Keyao Xie and Xuepeng Chen
Ceramics 2026, 9(2), 25; https://doi.org/10.3390/ceramics9020025 - 16 Feb 2026
Viewed by 849
Abstract
In response to the high stiffness and hardness levels of alumina ceramic materials, the traditional SHPB (split Hopkinson pressure bar) experimental setup has been modified. This study analyzes the propagation patterns of stress waves in the SHPB system after adding cushion blocks. Experiments [...] Read more.
In response to the high stiffness and hardness levels of alumina ceramic materials, the traditional SHPB (split Hopkinson pressure bar) experimental setup has been modified. This study analyzes the propagation patterns of stress waves in the SHPB system after adding cushion blocks. Experiments demonstrated that the modified SHPB apparatus can effectively perform dynamic mechanical property tests on alumina ceramics. The JH-2 constitutive damage model parameters for alumina ceramics were determined based on theoretical analysis and static/dynamic experimental data. An LS-DYNA numerical model for the impact compression simulation of alumina ceramics was established to investigate the effects of stress waves with three wavelengths (300 mm, 400 mm, and 600 mm) at the same impact velocity, along with the dynamic fragmentation process. The results indicate that alumina ceramics exhibit strain rate hardening effects in compressive strength, failure strain, and elastic modulus under high strain rates; compressive strength and failure strain show positive correlations with stress wave wavelength under high strain rates; and microcracks initially nucleate preferentially along grain boundaries on the end surfaces, forming annular damage zones symmetrically about the central axis. This study presents a modified SHPB setup that improves test capability for high-hardness ceramics, rather than overturning classical methodologies. The absence of a direct comparison with unmodified setups stems from the known limitations of conventional systems in handling small-diameter alumina specimens without bar damage—a challenge addressed proactively in this work through impedance-matched cushion blocks and refined data processing. Full article
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15 pages, 1755 KB  
Article
Simulation Study on Injection/Withdrawal Scenarios of Hydrogen-Blended Methane in a Depleted Gas Reservoir
by Yujin Kim and Hochang Jang
Energies 2026, 19(2), 374; https://doi.org/10.3390/en19020374 - 12 Jan 2026
Viewed by 510
Abstract
This study presents a quantitative simulation analysis of hydrogen-enriched methane (HENG) storage with nitrogen as the cushion-gas in a depleted gas reservoir by varying three key operational parameters: the injection/withdrawal period, hydrogen blending ratio (5–20%), and injection depth. Ten injection–withdrawal cycles were modeled [...] Read more.
This study presents a quantitative simulation analysis of hydrogen-enriched methane (HENG) storage with nitrogen as the cushion-gas in a depleted gas reservoir by varying three key operational parameters: the injection/withdrawal period, hydrogen blending ratio (5–20%), and injection depth. Ten injection–withdrawal cycles were modeled for each scenario, and performance was evaluated using cycle-averaged and cumulative hydrogen purity, recovery factors, and the mixing zone size. Extending the injection period increased hydrogen purity to 20.00–20.26% and reduced nitrogen to 0.001–0.003%, but recovery decreased from 65.63 to 53.83–41.09% due to enhanced dispersion and residual trapping. The blending ratio was the dominant control: 20% blending yielded 19.9–20.0% purity with nitrogen as low as 0.00–0.03%, whereas 5–10% blending produced lower purity but minimized nitrogen production to 0.97–1.08%. Injection depth affected nitrogen recovery more than purity, increasing from 0.72–1.20% (upper) to 1.46–1.61% (lower), along with thicker mixing zones. Final mixing zone size ranged from 3176 to 5546 blocks, with smaller zones consistently linked to higher purity and lower nitrogen breakthrough. The shut-in period further reduced nitrogen recovery from 6.49 to 1.33% and stabilized mixing behavior. Overall, minimizing late-cycle mixing zone thickness is essential for maintaining HENG storage performance. Although this study provides quantitative insights into HENG operational strategies, the use of a homogeneous grid and simplified fluid properties limits representation of geological heterogeneity and reactive processes. Future work will incorporate heterogeneity and reaction modeling into field-scale simulations to validate and refine these operating strategies for practical deployment. Full article
(This article belongs to the Topic Exploitation and Underground Storage of Oil and Gas)
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12 pages, 4677 KB  
Article
Preparation of Robust Superhydrophobic Surfaces Based on the Screen Printing Method
by Yinyu Sun, Qing Ding, Qiaoqiao Zhang, Yuting Xie, Zien Zhang, Yudie Pang, Zhongcheng Ke and Changjiang Li
Nanomaterials 2026, 16(2), 86; https://doi.org/10.3390/nano16020086 - 8 Jan 2026
Viewed by 665
Abstract
The bioinspired superhydrophobic surfaces have demonstrated many fascinating performances in fields such as self-cleaning, anti-corrosion, anti-icing, energy-harvesting devices, and antibacterial coatings. However, developing a low-cost, feasible, and scalable production approach to fabricate robust superhydrophobic surfaces has remained one of the main challenges in [...] Read more.
The bioinspired superhydrophobic surfaces have demonstrated many fascinating performances in fields such as self-cleaning, anti-corrosion, anti-icing, energy-harvesting devices, and antibacterial coatings. However, developing a low-cost, feasible, and scalable production approach to fabricate robust superhydrophobic surfaces has remained one of the main challenges in the past decades. In this paper, we propose an uncommon method for the fabrication of a durable superhydrophobic coating on the surface of the glass slide (GS). By utilizing the screen printing method and high-temperature curing, the epoxy resin grid (ERG) coating was uniformly and densely loaded on the surface of GS (ERG@GS). Subsequently, the hydrophobic silica (H-SiO2) was deposited on the surface of ERG@GS by the impregnation method, thereby obtaining a superhydrophobic surface (H-SiO2@ERG@GS). It is demonstrated that the micro-grooves in ERG can provide a large specific surface area for the deposition of low surface energy materials, while the micro-columns can offer excellent protection for the superhydrophobic coating when it is subjected to mechanical wear. It is important to note that micro-columns, micro-grooves, and nano H-SiO2 jointly form the micro–nano structure, providing a uniform and robust rough structure for the superhydrophobic surface. Therefore, the combination of a micro–nano rough structure, low surface energy material, and air cushion effect endow the material with excellent durability and superhydrophobic property. The results show that H-SiO2@ERG@GS possesses excellent self-cleaning property, mechanical durability, and chemical stability, indicating that this preparation method of the robust superhydrophobic coating has significant practical application value. Full article
(This article belongs to the Section Synthesis, Interfaces and Nanostructures)
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18 pages, 4211 KB  
Article
Fabrication and Drag Reduction Performance of Flexible Bio-Inspired Micro-Dimple Film
by Yini Cai, Yanjun Lu, Haopeng Gan, Yan Yu, Xiaoshuang Rao and Weijie Gong
Micromachines 2026, 17(1), 85; https://doi.org/10.3390/mi17010085 - 8 Jan 2026
Viewed by 635
Abstract
The flexible micro-structured surface found in biological skins exhibits remarkable drag reduction properties, inspiring applications in the aerospace industry, underwater exploration, and pipeline transportation. To address the challenge of efficiently replicating such structures, this study presents a composite flexible polymer film with a [...] Read more.
The flexible micro-structured surface found in biological skins exhibits remarkable drag reduction properties, inspiring applications in the aerospace industry, underwater exploration, and pipeline transportation. To address the challenge of efficiently replicating such structures, this study presents a composite flexible polymer film with a bio-inspired micro-dimple array, fabricated via an integrated process of precision milling, polishing, and micro-injection molding using thermoplastic polyurethane (TPU). We systematically investigated the influence of key injection parameters on the shape accuracy and surface quality of the film. The experimental results show that polishing technology can significantly reduce mold core surface roughness, thereby enhancing film replication accuracy. Among the parameters, melt temperature and holding time exerted the most significant effects on shape precision PV and bottom roughness Ra, while injection speed showed the least influence. Under optimized conditions of a melt temperature of 180 °C, injection speed of 60 mm/s, holding pressure of 7 MPa, and holding time of 13 s, the film achieved a micro-structure shape accuracy of 13.502 μm and bottom roughness of 0.033 μm. Numerical simulation predicted a maximum drag reduction rate of 10.26%, attributable to vortex cushion effects within the dimples. This performance was experimentally validated in a flow velocity range of 0.6–2 m/s, with the discrepancy between simulated and measured drag reduction kept within 5%, demonstrating the efficacy of the proposed manufacturing route for flexible bio-inspired drag reduction film. Full article
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15 pages, 4220 KB  
Article
Influence of Connective Architectures of Inlaid Weft-Knitted Spacer Fabric on Compression, Impact Force Absorption, and Vibration Isolation
by Shu-Ning Yan, Yi-Lei Wang and Annie Yu
Polymers 2026, 18(2), 151; https://doi.org/10.3390/polym18020151 - 6 Jan 2026
Viewed by 521
Abstract
Spacer fabrics are a breathable material option for wearable cushioning, but the cushioning performance is still not comparable to that of traditional elastomeric cushioning materials. The polymer-based connective structure of spacer fabrics largely affects fabric properties, compression, and mechanical performance, and this is [...] Read more.
Spacer fabrics are a breathable material option for wearable cushioning, but the cushioning performance is still not comparable to that of traditional elastomeric cushioning materials. The polymer-based connective structure of spacer fabrics largely affects fabric properties, compression, and mechanical performance, and this is a research gap that calls for the development of spacer fabrics with enhanced cushioning functions. This study develops a new square-wave inlay pattern and investigates the effects of the inlay structure and spatial frequency of the spacer course, as well as the effects of the silicone inlay on compression, impact force absorption, and vibration isolation of the spacer fabric. Twelve samples are designed and evaluated. The results show that the square-wave inlaid spacer fabric has higher energy absorption during compression. The square-wave pattern with a shorter transition distance between the front and back tuck stitches could increase the inclination angle close to a right angle, and extra tuck stitches on the surface float could secure the square-wave structure to enhance the impact force absorption ability. The increment in the spatial frequency of spacer courses provides a less stiff fabric with lower impact force absorption but higher vibration isolation ability. This study shows the innovative development of spacer fabric for enhancing cushioning properties. Full article
(This article belongs to the Special Issue Polymer-Based Functional Fabrics for Advanced Applications)
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20 pages, 5307 KB  
Article
Chitosan-Based Aerogel Cushioning Packaging for Improving Postharvest Quality of Wax Apples
by Yujie Hou, Sitong Zhou, Shiqi Liu, Peng Jin, Yonghua Zheng and Zhengguo Wu
Foods 2026, 15(2), 192; https://doi.org/10.3390/foods15020192 - 6 Jan 2026
Cited by 1 | Viewed by 850
Abstract
Mechanical damage and microbial contamination are major challenges in the postharvest logistics of perishable fruit. In this study, two types of functionally modified chitosan-based aerogel pads were developed to enhance cushioning and preservation of wax apples. A chitosan/polyvinyl alcohol (CP) aerogel was first [...] Read more.
Mechanical damage and microbial contamination are major challenges in the postharvest logistics of perishable fruit. In this study, two types of functionally modified chitosan-based aerogel pads were developed to enhance cushioning and preservation of wax apples. A chitosan/polyvinyl alcohol (CP) aerogel was first optimized by adjusting solid content, CS:PVA ratio, and crosslinker concentration. The optimal formulation (2% solids, 1:1 CS: PVA, 3% glutaraldehyde) exhibited a uniform porous structure and improved compressive strength. A chitosan/montmorillonite (CM) aerogel with 5% montmorillonite (MMT) showed high porosity, low density, and excellent cyclic stability. Incorporating 10% copper nanoparticle-loaded antibacterial fibers (CuNPs-TNF) into CM aerogels yielded CM-Cu aerogels with enhanced cushioning and antimicrobial properties. Under simulated transport and cold storage conditions, all aerogel-packaged groups reduced mechanical damage and decay of wax apples. Compared to the control, the CM-Cu group showed 66% lower decay, 5% less weight loss, 6 N greater firmness, 7% less juice yield, and a 13% reduction in relative electrical conductivity. Additionally, it better preserved fruit color and total soluble solids, extending shelf life by 4 d at 20 °C. These results demonstrate the potential of chitosan-based aerogels as multifunctional packaging materials that combine mechanical protection with antimicrobial activity for perishable fruit preservation. Full article
(This article belongs to the Special Issue Application and Safety of Edible Films in Food Packaging)
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23 pages, 1585 KB  
Article
Analysis of Thermodynamic Processes in Thermal Energy Storage Vessels
by Laszlo Garbai, Robert Santa and Mladen Bošnjaković
Thermo 2026, 6(1), 5; https://doi.org/10.3390/thermo6010005 - 6 Jan 2026
Viewed by 990
Abstract
To balance the quantity of heat generated and consumed, thermal energy storage systems are crucial for power plants and district heating systems. Particularly when phase transitions and pressure variations are not adequately covered in the existing literature, their work frequently takes place under [...] Read more.
To balance the quantity of heat generated and consumed, thermal energy storage systems are crucial for power plants and district heating systems. Particularly when phase transitions and pressure variations are not adequately covered in the existing literature, their work frequently takes place under complicated, changing temperature and fluid dynamic settings. The goal of this research is to create a thermodynamic model that incorporates the effects of steam condensation, steam injection, and heating failures to describe the transient behaviour of temperature and pressure in pressure vessels containing single-phase and two-phase fluids. To account for nonlinear, temperature-dependent steam properties, as well as initial and boundary constraints, the study proposes energy balance models for hot water and saturated steam cases. Numerical simulations evaluating sensitivity to parameter changes are presented alongside analytical solutions for isochoric and isobaric systems. The model also includes direct steam injection heating and the use of a heat exchanger. It explains the changes in temperature and pressure that occur in thermal energy storage systems over time, including significant events such as steam cushion collapse and condensate drainage. According to the sensitivity analysis, the main factors influencing the system’s safety limitations and transient dynamic phenomena are thermal power, heat exchanger capacity, and thermal insulation efficiency. The proposed thermodynamic model closes a major gap in the literature by providing reliable predictions of the transient behavior needed for the safe design and reliable operation of pressure vessels utilized for heat storage in district heating networks. This model can be used by engineers and researchers to optimize system design and steer clear of risky operational situations. Full article
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14 pages, 1358 KB  
Article
The Effect of Different Midsole Cushioning Types on Impact Forces and Joint Stiffness in Heel-Toe Runners
by Hyeong-Sik Kim and Sang-Kyoon Park
Appl. Sci. 2025, 15(24), 13132; https://doi.org/10.3390/app152413132 - 13 Dec 2025
Viewed by 1880
Abstract
(1) Background: The midsole hardness (i.e., cushioning) of running shoes has received significant attention as a crucial element influencing both performance and injury prevention. This research aimed to examine how variations in midsole hardness affect the biomechanical responses of the lower extremities during [...] Read more.
(1) Background: The midsole hardness (i.e., cushioning) of running shoes has received significant attention as a crucial element influencing both performance and injury prevention. This research aimed to examine how variations in midsole hardness affect the biomechanical responses of the lower extremities during running. (2) Methods: Twenty-five male recreational runners in their 20 s with no history of musculoskeletal injuries (age: 23.3 ± 4.24 years) were recruited. Custom-made shoes with four different midsole hardness levels (Asker-C 70, 60, 50, and 40) were used, and the mechanical properties of the midsoles were analyzed. Participants ran on an instrumented treadmill at speeds of 2.3 m/s and 3.3 m/s. Ground reaction forces and motion data were collected during the trials. A one-way repeated-measures ANOVA was conducted to compare groups. (3) Results: In the running trials, a decrease in midsole hardness increased the impact peak (IP) while loading rate (LR) decreased significantly (p < 0.05). In addition, runners wearing shoes with greater cushioning exhibited higher ankle joint stiffness than those wearing harder shoes (p < 0.05). (4) Conclusions: Adjusting joint stiffness appears to be a key strategy employed by runners in response to softer or cushioned running environments (i.e., shoe and surface), ultimately contributing to greater dynamic stability during movement. Full article
(This article belongs to the Special Issue Physiology and Biomechanical Monitoring in Sport)
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18 pages, 7162 KB  
Article
Experimental and Numerical Investigation on Fracture Behavior and Energy Absorption Characteristics of Aluminum Foam in the Taylor Tests
by Chenyang Fan, Xingyu Dong, Youcai Xiao and Wenzhong Lou
Metals 2025, 15(12), 1313; https://doi.org/10.3390/met15121313 - 28 Nov 2025
Viewed by 610
Abstract
This study investigates the dynamic response characteristics of aluminum foam materials under low to medium-high velocity impact loading, elucidating their deformation mechanisms and energy absorption capabilities through an integrated experimental and numerical simulation approach. The multi-stage deformation behavior of aluminum foam was investigated [...] Read more.
This study investigates the dynamic response characteristics of aluminum foam materials under low to medium-high velocity impact loading, elucidating their deformation mechanisms and energy absorption capabilities through an integrated experimental and numerical simulation approach. The multi-stage deformation behavior of aluminum foam was investigated through the Taylor impact test, which demonstrated that impact velocity significantly affects its stiffness and energy absorption capability. The accuracy of stress distribution and mechanical properties during the impact process is validated, and the deformation behavior under medium- and high-speed impact conditions is clearly revealed. Through integrated macroscopic and microscopic analyses, the dynamic response characteristics of aluminum foam under various impact loads are systematically investigated, elucidating the mechanisms of internal pore collapse and dynamic compressive behavior, thereby providing robust theoretical support for the optimized design of aluminum foam in cushioning and protective applications. Full article
(This article belongs to the Section Corrosion and Protection)
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21 pages, 2201 KB  
Review
The Future of Sustainable Packaging: Exploring Biodegradable Solutions Through Extrusion, Thermo-Expansion, 3D Printing and Supercritical Fluid from Agro-Industry Waste
by Lacan S. Rabelo, Fabrício C. Tanaka, Sidney S. dos Santos, Fauze A. Aouada and Márcia R. de Moura
Foods 2025, 14(23), 4027; https://doi.org/10.3390/foods14234027 - 24 Nov 2025
Cited by 1 | Viewed by 1723
Abstract
Due to environmental disasters caused by the use of plastic packaging, particularly expanded polystyrene (EPS), there is an urgent need to identify sustainable alternatives. Biodegradable foams derived from renewable polysaccharides have emerged as highly promising candidates to replace EPS, given their comparable cushioning [...] Read more.
Due to environmental disasters caused by the use of plastic packaging, particularly expanded polystyrene (EPS), there is an urgent need to identify sustainable alternatives. Biodegradable foams derived from renewable polysaccharides have emerged as highly promising candidates to replace EPS, given their comparable cushioning and barrier properties. However, despite the rapid growth of research in this area, there has not yet been a comprehensive review addressing biodegradable foams as a specific class of packaging materials, particularly regarding their processing routes, raw materials, and functionalization. This work discusses conventional techniques for producing biodegradable foams, such as thermoforming and extrusion, as well as innovative methods, including supercritical fluids and 3D printing. It also examines key renewable polysaccharides and the incorporation of agro-industrial residues into foam matrices, aiming to improve performance and reduce costs. Furthermore, the article highlights advances in composite and nanocomposite foams, with particular emphasis on active properties such as ethylene absorption and antimicrobial activity capable of extending food shelf life. By directing attention to biodegradable foams as substitutes for expanded polystyrene, this review provides a unique contribution, filling a critical gap in the field and offering a foundation for future studies aimed at developing scalable, low-cost, and eco-friendly alternatives to plastics. Full article
(This article belongs to the Section Food Packaging and Preservation)
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29 pages, 3118 KB  
Article
Impact of Compaction Parameters and Techniques on MUPS Tablets
by Daniel Robin Thio, Paul Wan Sia Heng and Lai Wah Chan
Pharmaceutics 2025, 17(10), 1347; https://doi.org/10.3390/pharmaceutics17101347 - 18 Oct 2025
Viewed by 1215
Abstract
Background/Objectives: Compaction of sustained release coated pellets into tablets is associated with damage to the functional coat and loss in sustained release. The influences of precompression, trilayering, and tableting rate on the compaction of sustained release coated pellets into tablets are not well [...] Read more.
Background/Objectives: Compaction of sustained release coated pellets into tablets is associated with damage to the functional coat and loss in sustained release. The influences of precompression, trilayering, and tableting rate on the compaction of sustained release coated pellets into tablets are not well defined and were herein investigated to enhance the current limited understanding of these factors. Methods: Pellets coated with acrylic polymer (AC) or ethylcellulose (EC) were combined with filler material and compacted into multi-unit pellet system (MUPS) tablets prepared using different levels of precompression, as a trilayered MUPS tablet and at different tableting rates. The physical properties of the resulting MUPS tablets were evaluated. Trilayering was achieved by adding cushioning layers at the top and bottom of the MUPS tablet to avoid direct contact of pellets with punch surfaces. Results: With precompression, slightly stronger MUPS tablets were made compared to the tablets without precompression for EC pellets but not AC pellets. However, precompression led to a slight reduction in pellet coat damage for AC pellets but not EC pellets. Trilayering led to significant reductions in pellet coat damage and significant increases in tablet tensile strength. When EC pellets were lubricated with sodium stearyl fumarate, pellet coat damage was significantly lower. Increasing the tableting rate from 20 to 100 rpm did not result in increased pellet coat damage but in significantly weaker tablets due to the shorter dwell time. Conclusions: This study provides key insights on how compaction parameters and techniques could be altered to produce better MUPS tablets. Full article
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14 pages, 2482 KB  
Article
Multiscale Structural Engineering of Cellulose Foams: Performance Characterization and Fiber Imaging
by Patricija Pevec, Urška Kavčič, Aleš Hladnik and Diana Gregor-Svetec
Polymers 2025, 17(17), 2355; https://doi.org/10.3390/polym17172355 - 29 Aug 2025
Cited by 2 | Viewed by 1438
Abstract
The paper industry is always looking for possible solutions for new fiber-based products, such as protective and cushioning materials. These materials must be carefully designed to provide effective cushioning while also being lightweight to reduce transportation costs. Additionally, they need to offer protection [...] Read more.
The paper industry is always looking for possible solutions for new fiber-based products, such as protective and cushioning materials. These materials must be carefully designed to provide effective cushioning while also being lightweight to reduce transportation costs. Additionally, they need to offer protection from environmental and mechanical damage, besides having good processability to ensure proper buffering. The widely used protective and cushioning materials, such as plastic foams and expanded or extruded polystyrene, create significant disposal challenges. Therefore, there is increasing demand for biodegradable and sustainable materials for cushioning applications. The focus of our research was to develop fiber-based foams and investigate the influence of different compositions (hardwood and softwood) of cellulose fibers on the basic (mass, thickness, density) and mechanical properties (three-point bend test, tensile properties). Foams made entirely from short eucalyptus fibers (100S) exhibited the highest density (28.0 ± 0.34 kg/m3) and lowest thickness (38.82 ± 4.21 mm), resulting in superior tensile strength and elastic modulus but lower strain at break. In contrast, foams composed of long spruce fibers (100L) had the lowest density (19.0 ± 0.27 kg/m3) and highest thickness (58.52 ± 1.50 mm), with lower strength and stiffness but much higher ductility and porosity (confirmed by ~30% higher air permeability compared to 100S). Blended formulations demonstrated intermediate behavior, with the 50S50L foam showing a favorable balance of strength, stiffness, and flexibility. Visual analysis confirmed heterogeneous fiber distribution with localized agglomerates and compaction at the bottom layer due to casting. To further interpret the complex relationships within the dataset and uncover patterns, Principal Component Analysis (PCA) was applied to all experimental results. The findings of the research contribute to the broader understanding of how different fiber types and blends impact the performance of sustainable cellulose-based foams, with potential implications for the development of biodegradable packaging and lightweight construction materials. Full article
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24 pages, 3590 KB  
Article
Palmitic Acid Esterification Boosts Epigallocatechin Gallate’s Immunomodulatory Effects in Intestinal Inflammation
by Raúl Domínguez-Perles, Concepción Medrano-Padial, Cristina García-Viguera and Sonia Medina
Biomolecules 2025, 15(8), 1208; https://doi.org/10.3390/biom15081208 - 21 Aug 2025
Cited by 2 | Viewed by 1646
Abstract
Lipophenols, combining phenolic and lipid moieties in a single molecule, are valuable candidates for providing enhanced bioactive properties with therapeutic potential, including anti-inflammatory functions associated with immune-mediated diseases such as intestinal bowel disease (IBD). Thus, palmitoyl–epigallocatechin gallate (PEGCG), a lipophilic derivative of epigallocatechin [...] Read more.
Lipophenols, combining phenolic and lipid moieties in a single molecule, are valuable candidates for providing enhanced bioactive properties with therapeutic potential, including anti-inflammatory functions associated with immune-mediated diseases such as intestinal bowel disease (IBD). Thus, palmitoyl–epigallocatechin gallate (PEGCG), a lipophilic derivative of epigallocatechin gallate (EGCG), has been highlighted for its enhanced stability in lipid-rich environments and bioavailability due to improved cellular uptake. However, the contribution of lipophilic esterification to PEGCG’s capacity to inhibit inflammation and the development of harmful autoimmune responses remains underexplored. This work uncovered the differential efficiency of EGCG and its palmitoyl derivative in modulating, in vitro, the interleukin profile generated by intestinal epithelium under inflammatory conditions. Therefore, both could attenuate the immune response by lowering macrophage migration and polarisation towards pro-inflammatory (M1) or anti-inflammatory (M2) phenotypes. While the fatty acid moiety gave PEGCG a functional advantage over EGCG in adjusting the interleukin-based response of intestinal epithelium to inflammation—since both of them decreased, to a similar extent, the expression of pro-inflammatory interleukins, namely IL-6, IL-17, IL-18, IL-23, and TNF-α (which lowered by 11.2%, on average)—the former was significantly more efficient in cushioning the increase in IL-1β and IL-12p70 (by 9.2% and 10.4%, respectively). This immune modulation capacity did not significantly impact the migration and expression of costimulatory molecules featuring M1 (CD86+) or M2 (CD206+) phenotypes by THP-1-derived macrophages, for which both bioactive compounds exhibited equivalent efficiency. Nonetheless, the analysis of the pro- and anti-inflammatory interleukins secreted by differentiated macrophages allowed the identification of an advantage for PEGCG, which decreased the expression of the pro-inflammatory immune mediators IL-1β and IL-12p70, IL-23, and TNF-α more efficiently. These results suggest that lipophilisation of phenolic compounds presents exciting potential for extending their application as functional molecules by combining the effects of their polar head with their ability to interfere with membranes, conveyed by their lipophilic tail. In addition, the enhanced reactivity would confer a higher capacity to interact with cellular signalling molecules and thus inhibit or attenuate the immune response, which is of special interest for preventing the onset and severity of immune-mediated pathologies such as IBD. Full article
(This article belongs to the Special Issue Recent Advances in the Enzymatic Synthesis of Bioactive Compounds)
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