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Article

38 Citations

5,388 Views

13 Pages

MicroRNA-15a Regulates the Differentiation of Intramuscular Preadipocytes by Targeting ACAA1, ACOX1 and SCP2 in Chickens

Guoxi Li,
Shouyi Fu,
Yi Chen,
Wenjiao Jin,
Bin Zhai,
Yuanfang Li,
Guirong Sun,
Ruili Han,
Yanbin Wang and
Yadong Tian
+ 2 authors

Int. J. Mol. Sci.2019, 20(16), 4063;https://doi.org/10.3390/ijms20164063

20 August 2019

Our previous studies showed that microRNA-15a (miR-15a) was closely related to intramuscular fat (IMF) deposition in chickens; however, its regulatory mechanism remains unclear. Here, we evaluated the expression characteristics of miR-15a and its rel...

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Article

23 Citations

3,218 Views

15 Pages

miR-24-3p Dominates the Proliferation and Differentiation of Chicken Intramuscular Preadipocytes by Blocking ANXA6 Expression

Zhongzhen Lin,
Yuan Tang,
Zhiqiang Li,
Jingjing Li,
Chunlin Yu,
Chaowu Yang,
Li Liu,
Yan Wang and
Yiping Liu

Genes2022, 13(4), 635;https://doi.org/10.3390/genes13040635

2 April 2022

Intramuscular fat (IMF) is one of the crucial factors determining meat quality. IMF deposition depends on the hyperplasia and hypertrophy of intramuscular preadipocytes, in which genes and noncoding RNAs play an important regulatory role. According t...

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Article

1 Citations

726 Views

14 Pages

LincRNA-MSTRG.673.2 Promotes Chicken Intramuscular Adipocyte Differentiation by Sponging miR-128-3p

Binbin Zhang,
Shuaipeng Zhu,
Yuehua He,
Wenjie Liang,
Tingqi Zhu,
Ruili Han,
Donghua Li,
Yanbin Wang,
Yadong Tian and
Guoxi Li
+ 3 authors

Animals2025, 15(13), 1879;https://doi.org/10.3390/ani15131879

25 June 2025

Background: Intramuscular fat content is positively correlated with meat flavor and juiciness. Increasing the intramuscular fat (IMF) content of chickens while increasing their growth rate has become a hot topic in molecular breeding. The group&rsquo...

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Article

46 Citations

5,385 Views

20 Pages

gga-miRNA-18b-3p Inhibits Intramuscular Adipocytes Differentiation in Chicken by Targeting the ACOT13 Gene

Guirong Sun,
Fang Li,
Xiangfei Ma,
Junwei Sun,
Ruirui Jiang,
Yadong Tian,
Ruili Han,
Guoxi Li,
Yanbin Wang and
Zhuanjian Li
+ 2 authors

Cells2019, 8(6), 556;https://doi.org/10.3390/cells8060556

7 June 2019

Intramuscular fat (IMF) is the most important evaluating indicator of chicken meat quality, the content of which is positively correlated with tenderness, flavor, and succulence of the meat. Chicken IMF deposition process is regulated by many factors...

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Article

1 Citations

1,504 Views

18 Pages

Regulatory Effects of 198-bp Structural Variants in the GSTA2 Promoter Region on Adipogenesis in Chickens

Wangyu Li,
Meng Xu,
Zihao Zhang,
Jiaying Liang,
Rong Fu,
Wujian Lin,
Wen Luo,
Xiquan Zhang and
Tuanhui Ren

Int. J. Mol. Sci.2024, 25(13), 7155;https://doi.org/10.3390/ijms25137155

28 June 2024

Molecular breeding accelerates animal breeding and improves efficiency by utilizing genetic mutations. Structural variations (SVs), a significant source of genetic mutations, have a greater impact on phenotypic variation than SNPs. Understanding SV f...

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