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Keywords = biomedical microwave imaging

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32 pages, 3968 KB  
Article
Validation-Aware Surrogate Shortlisting for Biomedical Microwave Imaging: Analytical Performance and FDTD Transfer
by Lulu Wang
Electronics 2026, 15(16), 3561; https://doi.org/10.3390/electronics15163561 - 11 Aug 2026
Viewed by 162
Abstract
Broadband antenna, frequency and channel selection requires efficient prioritisation of finite candidate configurations, yet strong surrogate performance within a simplified analytical model does not ensure that the learned ordering will transfer to another electromagnetic representation. This study developed a validation-aware surrogate-shortlisting framework using [...] Read more.
Broadband antenna, frequency and channel selection requires efficient prioritisation of finite candidate configurations, yet strong surrogate performance within a simplified analytical model does not ensure that the learned ordering will transfer to another electromagnetic representation. This study developed a validation-aware surrogate-shortlisting framework using a controlled breast-mimetic benchmark comprising 120 scenarios and 80 antenna–frequency–channel candidates per scenario. Surrogate models were developed using grouped scenario-level validation, and the model and five-candidate shortlist policy were frozen before external evaluation. Random forest produced the lowest-regret analytical-domain shortlist and remained stable across model-initialisation seeds. The frozen ranking was then challenged on held-out scenarios using a separately implemented restricted two-dimensional transverse-magnetic finite-difference time-domain model. Although numerical-reference checks supported shortlist-level use of the operational grid, candidate ordering did not transfer reliably: optimum inclusion, shortlist agreement and rank association were weak, although a qualified candidate within 2 mm of the finite-library FDTD optimum was retained in 58.3% of cases. Transfer failure varied by frequency band and channel family, while incomplete alignment between the analytical and FDTD candidate libraries prevented attribution of the discrepancy to electromagnetic-model shift alone. The framework therefore positions analytical surrogates as auditable shortlisting tools that reduce downstream candidate-level assessment while retaining independent electromagnetic evaluation before final design selection. Full article
(This article belongs to the Special Issue AI-Driven Metasurfaces, Antennas, and Wireless Systems)
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31 pages, 3300 KB  
Review
Active Wavelength Control of Fiber Bragg Gratings: A Systematic Review of Tuning Mechanisms, Emerging Applications, and Future Frontiers
by Xiaoyan Wang, Erdong Xia, Chunrong Wang and Wen Ren
Micromachines 2026, 17(2), 263; https://doi.org/10.3390/mi17020263 - 19 Feb 2026
Viewed by 2230
Abstract
Fiber Bragg gratings (FBGs) have evolved from passive sensing elements into actively programmable photonic components, enabling dynamic wavelength control across diverse applications. This review provides a comprehensive and systematic overview of active wavelength control technologies for FBGs, deliberately excluding passive sensing applications. We [...] Read more.
Fiber Bragg gratings (FBGs) have evolved from passive sensing elements into actively programmable photonic components, enabling dynamic wavelength control across diverse applications. This review provides a comprehensive and systematic overview of active wavelength control technologies for FBGs, deliberately excluding passive sensing applications. We systematically categorize the fundamental tuning mechanisms—including mechanical, thermal, optothermal, electro-optic, nonlinear optical, and hybrid approaches—and compare their performance characteristics in terms of tuning range, speed, precision, and trade-offs. Key enhancement techniques, such as mechanical amplification, thermal packaging, femtosecond laser fabrication, and FPGA-based interrogation, are examined. The transformative impact of actively controlled FBGs is elucidated across three major application domains: tunable and narrow-linewidth fiber lasers, reconfigurable microwave photonic systems, and emerging fields including quantum information processing and biomedical imaging. A consolidated technology map visualizes the connections between enabling techniques and applications. Finally, we critically analyze core challenges—performance trade-offs, control complexity, and integration bottlenecks—and outline future research directions driven by novel materials, artificial intelligence, and quantum technologies. This review offers a structured framework for understanding active FBGs as programmable photonic primitives, providing actionable insights for researchers and engineers in academia and industry. Full article
(This article belongs to the Section E:Engineering and Technology)
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24 pages, 6227 KB  
Article
Gadolinium-Doped Hydroxyapatite Nanoparticles Functionalized with Curcumin and Folic Acid: Structural Insights and Magnetic Behavior for Theranostic Applications
by Jéssica P. N. Marinho, Luísa A. F. Vieira, André F. Oliveira, Aloísio M. Garcia, Monica E. B. Guarin, João Batista S. Barbosa, Yan F. X. Ladeira, Adolfo H. M. Silva and Edésia M. B. de Sousa
Materials 2026, 19(3), 449; https://doi.org/10.3390/ma19030449 - 23 Jan 2026
Viewed by 781
Abstract
Gadolinium-doped hydroxyapatite nanoparticles (HapGd NPs) have emerged as promising multifunctional platforms for biomedical applications due to their unique combination of biocompatibility, structural tunability, and magnetic responsiveness. In this work, HapGd nanoparticles were synthesized using a microwave-assisted method and subsequently functionalized with curcumin and [...] Read more.
Gadolinium-doped hydroxyapatite nanoparticles (HapGd NPs) have emerged as promising multifunctional platforms for biomedical applications due to their unique combination of biocompatibility, structural tunability, and magnetic responsiveness. In this work, HapGd nanoparticles were synthesized using a microwave-assisted method and subsequently functionalized with curcumin and folic acid to enhance therapeutic efficiency and selective targeting. The synthesized nanostructures were characterized using various techniques, including X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier-transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), vibrating sample magnetometry (VSM), and relaxometry. Structural analyses revealed successful incorporation of Gd3+ ions into the Hap lattice, resulting in reduced unit cell volume and slight lattice distortion, while preserving the apatite crystalline framework. Surface functionalization with curcumin and folic acid was confirmed through spectroscopic characterization, demonstrating effective molecular attachment. Nuclear Magnetic Resonance (NMR) relaxation measurements indicated that Gd doping endowed paramagnetic behavior suitable for contrast enhancement in magnetic resonance imaging (MRI). Relaxometry studies revealed a strong linear correlation between 1/T1 and the Gd3+ concentration, especially in the functionalized samples, with performance comparable to the commercial contrast agent Omniscan™. The developed HapGd-based nanoplatform exhibits integrated diagnostic and therapeutic potential, providing a foundation for future research in biomedical applications. Full article
(This article belongs to the Special Issue Materials for Drug Delivery and Medical Engineering)
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32 pages, 6247 KB  
Review
Combined Use of Microwave Sensing Technologies and Artificial Intelligence for Biomedical Monitoring and Imaging
by Andrea Martínez-Lozano, Alejandro Buitrago-Bernal, Langis Roy, José María Vicente-Samper and Carlos G. Juan
Biosensors 2026, 16(1), 67; https://doi.org/10.3390/bios16010067 - 22 Jan 2026
Cited by 3 | Viewed by 2176
Abstract
Microwave sensing technology is rapidly advancing and increasingly finding its way into biomedical applications, promising significant improvements for medical care. Concurrently, the rise of artificial intelligence (AI) is enabling significant enhancements in the biomedical domain. Close scrutiny of the recent literature reveals intense [...] Read more.
Microwave sensing technology is rapidly advancing and increasingly finding its way into biomedical applications, promising significant improvements for medical care. Concurrently, the rise of artificial intelligence (AI) is enabling significant enhancements in the biomedical domain. Close scrutiny of the recent literature reveals intense activity in both fields, with particularly impactful outcomes deriving from the combined use of advanced microwave techniques and AI for biomedical monitoring. In this review, an up-to-date compilation, from the perspective of the authors, of the most significant works published on these topics in recent years is given, focusing on their integration and current challenges. With the objective of analyzing the current landscape, we survey and compare state-of-the-art biosensors and imaging systems at all healthcare levels, from outpatient contexts to specialized medical equipment and laboratory analysis tools. We also delve into the relevant applications of AI in medicine for processing microwave-derived data. As our core focus, we analyze the synergistic integration of AI in the design of microwave devices and the processing of the acquired data, which have shown notable performances, opening new avenues for compact, affordable, and multi-functional medical devices. We conclude by synthesizing the prevailing technical, algorithmic, and translational challenges that must be addressed to realize this potential. Full article
(This article belongs to the Special Issue AI-Enabled Biosensor Technologies for Boosting Medical Applications)
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14 pages, 2347 KB  
Article
Fabrication and Dielectric Characterization of Stable Oil in Gelatin Breast Tissue Phantoms for Microwave Biomedical Imaging
by Héctor López-Calderón, Víctor Velázquez-Martínez, Celia Calderón-Ramón, Juan Rodrigo Laguna-Camacho, Benoit Roger-Fouconnier, Jaime Martínez-Castillo, Enrique López-Calderón, Javier Calderón-Sánchez, Jorge Chagoya-Ramírez and Armando Aguilar-Meléndez
Micromachines 2025, 16(10), 1189; https://doi.org/10.3390/mi16101189 - 21 Oct 2025
Cited by 1 | Viewed by 1455
Abstract
Breast tissue-mimicking phantoms are essential tools for validating microwave imaging systems designed for early breast cancer detection. In this work, we report the fabrication and comprehensive characterization of oil-in-gelatin phantoms emulating normal, benign, and malignant breast tissues. The phantoms were manufactured with controlled [...] Read more.
Breast tissue-mimicking phantoms are essential tools for validating microwave imaging systems designed for early breast cancer detection. In this work, we report the fabrication and comprehensive characterization of oil-in-gelatin phantoms emulating normal, benign, and malignant breast tissues. The phantoms were manufactured with controlled mixtures of kerosene, safflower oil, and gelatin, and their dielectric properties were experimentally evaluated using a free-space transmission method with a Vector Network Analyzer across the 100 MHz–10 GHz range. Results demonstrated significant contrast in permittivity and conductivity among the different tissue types, consistent with values reported in the literature. Long-term stability was confirmed for up to six months under controlled storage. Additional structural and thermal characterization was performed using Fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC), and thermogravimetric analysis (TGA), providing insight into molecular composition and thermal response. The proposed method enables reproducible, low-cost, and stable phantom fabrication, offering reliable tissue models to support experimental validation and optimization of microwave-based breast cancer detection systems. Full article
(This article belongs to the Section B2: Biofabrication and Tissue Engineering)
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28 pages, 2156 KB  
Review
Au QDs in Advanced Biomedicine: Fluorescent, Biocompatible, and Multifunctional Nanoprobes for Imaging, Diagnostics, and Targeted Drug Delivery
by Nutan Shukla, Aayushi Chanderiya, Ratnesh Das, Elizaveta A. Mukhanova, Alexander V. Soldatov and Sabrina Belbekhouche
J. Nanotheranostics 2025, 6(3), 25; https://doi.org/10.3390/jnt6030025 - 8 Sep 2025
Viewed by 3320
Abstract
AuQDs (Au quantum dots) are ultrasmall nanostructures that combine the size-tunable fluorescence and photostability of semiconductor quantum dots with the chemical stability, low toxicity, and versatile surface chemistry of gold nanoparticles. This unique combination endows AuQDs with exceptional biocompatibility and multifunctionality, making them [...] Read more.
AuQDs (Au quantum dots) are ultrasmall nanostructures that combine the size-tunable fluorescence and photostability of semiconductor quantum dots with the chemical stability, low toxicity, and versatile surface chemistry of gold nanoparticles. This unique combination endows AuQDs with exceptional biocompatibility and multifunctionality, making them ideal for biomedical applications such as cellular imaging, real-time tracking, targeted drug delivery, diagnostics, therapeutic monitoring, and biosensing. Various synthesis methods—including chemical reduction, hydrothermal, laser ablation, and microwave-assisted techniques—allow for precise control over size and surface properties, optimizing fluorescence and electronic behavior for high-resolution imaging and sensitive detection. Compared to traditional quantum dots, AuQDs offer enhanced safety and biocompatibility, while surpassing larger gold nanoparticles by enabling fluorescence-based imaging. Their surfaces can be functionalized with diverse ligands for targeted delivery and specific biological interactions. In summary, AuQDs are multifunctional nanoprobes that combine superior optical properties, chemical stability, and biocompatibility, making them powerful tools for advanced biomedical diagnostics, therapy, and biosensing. Full article
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19 pages, 5086 KB  
Article
Expedited Near-Field Holographic Microwave Imaging with an Azimuthally Distributed Antenna Array
by Mona Heydari and Reza K. Amineh
Electronics 2025, 14(13), 2518; https://doi.org/10.3390/electronics14132518 - 20 Jun 2025
Viewed by 1783
Abstract
In this article, we propose a novel near-field holographic microwave imaging technique designed to accelerate the data acquisition process. The system employs a novel electronic switching mechanism utilizing two switching networks that virtually rotate the transmitting and receiving antennas along the azimuthal direction [...] Read more.
In this article, we propose a novel near-field holographic microwave imaging technique designed to accelerate the data acquisition process. The system employs a novel electronic switching mechanism utilizing two switching networks that virtually rotate the transmitting and receiving antennas along the azimuthal direction for efficient data collection. This minimizes the need for mechanical scanning of the antennas which, in turn, leads to faster data acquisition. To enhance the quality of the imaging outcome, the number of samples can be increased by combining only a few mechanical scanning steps with the electronic scanning. This data acquisition scheme leverages the system’s space-invariant property to enable convolution-based near-field holographic microwave image reconstruction. By capturing and processing scattered fields over a cylindrical aperture, the system achieves high-resolution imaging of concealed objects across multiple range positions. Both simulation and experimental results validate the effectiveness of the proposed approach in delivering high-quality imaging results. Its ability to provide faster and enhanced imaging outcomes highlights its potential for a wide range of applications, including biomedical imaging, security screening, and non-destructive testing of the materials. Full article
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33 pages, 1666 KB  
Review
Synthesis, Characterization, and Application of Magnetic Zeolite Nanocomposites: A Review of Current Research and Future Applications
by Sabina Vohl, Irena Ban, Janja Stergar and Mojca Slemnik
Nanomaterials 2025, 15(12), 921; https://doi.org/10.3390/nano15120921 - 13 Jun 2025
Cited by 14 | Viewed by 4201
Abstract
Magnetic zeolite nanocomposites (NCs) have emerged as a promising class of hybrid materials that combine the high surface area, porosity, and ion exchange capacity of zeolites with the magnetic properties of nanoparticles (NPs), particularly iron oxide-based nanomaterials. This review provides a comprehensive overview [...] Read more.
Magnetic zeolite nanocomposites (NCs) have emerged as a promising class of hybrid materials that combine the high surface area, porosity, and ion exchange capacity of zeolites with the magnetic properties of nanoparticles (NPs), particularly iron oxide-based nanomaterials. This review provides a comprehensive overview of the synthesis, characterization, and diverse applications of magnetic zeolite NCs. We begin by introducing the fundamental properties of zeolites and magnetic nanoparticles (MNPs), highlighting their synergistic integration into multifunctional composites. The structural features of various zeolite frameworks and their influence on composite performance are discussed, along with different interaction modes between MNPs and zeolite matrices. The evolution of research on magnetic zeolite NCs is traced chronologically from its early stages in the 1990s to current advancements. Synthesis methods such as co-precipitation, sol–gel, hydrothermal, microwave-assisted, and sonochemical approaches are systematically compared, emphasizing their advantages and limitations. Key characterization techniques—including X-Ray Powder Diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), Scanning and Transmission Electron Microscopy (SEM, TEM), Thermogravimetric Analysis (TGA), Nitrogen Adsorption/Desorption (BET analysis), Vibrating Sample Magnetometry (VSM), Zeta potential analysis, Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES), and X-Ray Photoelectron Spectroscopy (XPS)—are described, with attention to the specific insights they provide into the physicochemical, magnetic, and structural properties of the NCs. Finally, the review explores current and potential applications of these materials in environmental and biomedical fields, focusing on adsorption, catalysis, magnetic resonance imaging (MRI), drug delivery, ion exchange, and polymer modification. This article aims to provide a foundation for future research directions and inspire innovative applications of magnetic zeolite NCs. Full article
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12 pages, 2386 KB  
Communication
A Line-Source Approach for Simulating MammoWave Microwave Imaging Apparatus for Breast Lesion Detection
by Navid Ghavami, Sandra Dudley, Mohammad Ghavami and Gianluigi Tiberi
Sensors 2025, 25(12), 3640; https://doi.org/10.3390/s25123640 - 10 Jun 2025
Cited by 1 | Viewed by 1815
Abstract
Here, we propose an analytical approach to simulating MammoWave, a novel apparatus for breast cancer detection using microwave imaging. The approach is built upon the theory of cylindrical waves emitted by line sources. The sample is modelled as a cylinder with an inclusion. [...] Read more.
Here, we propose an analytical approach to simulating MammoWave, a novel apparatus for breast cancer detection using microwave imaging. The approach is built upon the theory of cylindrical waves emitted by line sources. The sample is modelled as a cylinder with an inclusion. Our results indicate that when compared with phantom measurements, our approach gives an average relative error (between the image generated through measurement with phantoms and the image generated through the analytical simulation approach) of less than 6% when considering the full frequency band of 1–9 GHz. The procedure permits the simulation of the MammoWave imaging system loaded with multilayered eccentric cylinders; thus, it can be used to obtain an insight into MammoWave’s detection capability, without having to perform either time-consuming full-wave simulations or phantom measurements. Full article
(This article belongs to the Special Issue Advances in Magnetic Sensors and Their Applications)
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16 pages, 4979 KB  
Article
Non-Uniform Antenna Array for Enhanced Medical Microwave Imaging
by Younis M. Abbosh, Kamel Sultan, Lei Guo and Amin Abbosh
Sensors 2025, 25(10), 3174; https://doi.org/10.3390/s25103174 - 17 May 2025
Cited by 8 | Viewed by 2424
Abstract
A non-uniform antenna array is proposed to enhance the accuracy of medical microwave imaging systems by increasing the amount of useful information captured about the imaged domain without increasing the number of antennas. These systems have so far been using uniform antenna arrays, [...] Read more.
A non-uniform antenna array is proposed to enhance the accuracy of medical microwave imaging systems by increasing the amount of useful information captured about the imaged domain without increasing the number of antennas. These systems have so far been using uniform antenna arrays, which lead to highly correlated signals, limiting the amount of imaging information and adversely affecting diagnostic accuracy. In the proposed non-uniform antenna array method, the optimal number and positions of antennas are calculated with the aim of enhancing spatial diversity and reducing information redundancy. The mutual information coefficient is used as a metric to evaluate and minimize redundancy between received signals. A microwave head imaging system is used to verify the proposed approach. The results of the investigated scenarios show that using a non-uniform antenna configuration outperforms a uniform setup in imaging accuracy and clarity, when using the same number of antennas. Moreover, the reconstructed images demonstrate that using an optimized non-uniform antenna array with fewer elements can outperform a uniform array with more elements in terms of localization accuracy and image quality. The proposed approach improves imaging performance and reduces system complexity, cost, and power consumption, making it a practical solution for real-world biomedical imaging applications. Full article
(This article belongs to the Special Issue Microwaves for Biomedical Applications and Sensing)
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15 pages, 5562 KB  
Review
Avalanche Multiplication in Two-Dimensional Layered Materials: Principles and Applications
by Zhangxinyu Zhou, Mengyang Kang, Yueyue Fang, Piotr Martyniuk and Hailu Wang
Nanomaterials 2025, 15(9), 636; https://doi.org/10.3390/nano15090636 - 22 Apr 2025
Cited by 2 | Viewed by 2635
Abstract
The avalanche multiplication effect, capable of significantly amplifying weak optical or electrical signals, plays a pivotal role in enhancing the performance of electronic and optoelectronic devices. This effect has been widely employed in devices such as avalanche photodiodes, impact ionization avalanche transit time [...] Read more.
The avalanche multiplication effect, capable of significantly amplifying weak optical or electrical signals, plays a pivotal role in enhancing the performance of electronic and optoelectronic devices. This effect has been widely employed in devices such as avalanche photodiodes, impact ionization avalanche transit time diode, and impact ionization field-effect transistors, enabling diverse applications in biomedical imaging, 3D LIDAR, high-frequency microwave circuits, and optical fiber communications. However, the evolving demands in these fields require avalanche devices with superior performance, including lower power consumption, reduced avalanche threshold energy, higher efficiency, and improved sensitivity. Over the years, significant efforts have been directed towards exploring novel device architectures and multiplication mechanisms. The emergence of two-dimensional (2D) materials, characterized by their exceptional light-matter interaction, tunable bandgaps, and ease of forming junctions, has opened up new avenues for developing high-performance avalanche devices. This review provides an overview of carrier multiplication mechanisms and key performance metrics for avalanche devices. We discuss several device structures leveraging the avalanche multiplication effect, along with their electrical and optoelectronic properties. Furthermore, we highlight representative applications of avalanche devices in logic circuits, optoelectronic components, and neuromorphic computing systems. By synthesizing the principles and applications of the avalanche multiplication effect, this review aims to offer insightful perspectives on future research directions for 2D material-based avalanche devices. Full article
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16 pages, 8389 KB  
Article
Safety Assessment of Microwave Breast Imaging: Heating Analysis on Digital Breast Phantoms
by Alessandra Ronca, Luca Zilberti, Oriano Bottauscio, Gianluigi Tiberi and Alessandro Arduino
Appl. Sci. 2025, 15(8), 4262; https://doi.org/10.3390/app15084262 - 12 Apr 2025
Cited by 1 | Viewed by 2158
Abstract
The impact of breast cancer on public health is serious, and due to risk/benefit assessment, screening programs are usually restricted to women older than 49 years. Microwave imaging devices offer advantages such as non-ionizing radiation, low cost, and the ability to distinguish between [...] Read more.
The impact of breast cancer on public health is serious, and due to risk/benefit assessment, screening programs are usually restricted to women older than 49 years. Microwave imaging devices offer advantages such as non-ionizing radiation, low cost, and the ability to distinguish between cancerous and healthy tissues due to their electrical properties. Ensuring the safety of this technology is vital for its potential clinical application. To estimate the temperature increase in breast tissues from a microwave imaging scanner, cases of healthy, benign, and malignant breast tissues were analyzed using three digital models and adding two healthy breast models with varying densities. Virtual experiments were conducted using the Sim4Life software (version 7.2) with a system consisting of a horn antenna in transmission and a Vivaldi antenna in reception. Temperature increases were estimated based on the Specific Absorption Rate distributions computed for different configurations and frequencies. The highest temperature increase obtained in this analysis is lower than 60 μK in fibroglandular tissue or skin, depending on the frequency and breast density. The presence of a receiving antenna acting as a scatterer modifies the temperature increase, which is almost negligible. Microwave examination can be performed without harmful thermal effects due to electromagnetic field exposure. Full article
(This article belongs to the Special Issue Antennas for Next-Generation Electromagnetic Applications)
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17 pages, 4380 KB  
Article
Stroke Detection and Monitoring by Means of a Multifrequency Microwave Inversion Approach
by Alessandro Fedeli, Valentina Schenone, Claudio Estatico and Andrea Randazzo
Electronics 2025, 14(3), 543; https://doi.org/10.3390/electronics14030543 - 29 Jan 2025
Cited by 3 | Viewed by 3039
Abstract
In the area of biomedical diagnostics, microwave imaging techniques have been recently proposed for performing brain stroke detection and monitoring. Indeed, theoretically, these techniques make it possible to meet the timeliness requirements of such a diagnosis with portable systems. Moreover, relying on the [...] Read more.
In the area of biomedical diagnostics, microwave imaging techniques have been recently proposed for performing brain stroke detection and monitoring. Indeed, theoretically, these techniques make it possible to meet the timeliness requirements of such a diagnosis with portable systems. Moreover, relying on the use of microwaves, they are noninvasive and allow continuous monitoring of critical patients. In this paper, the microwave imaging problem is solved by exploiting multifrequency data by an inexact-Newton method formulated in the framework of non-constant exponent Lebesgue spaces. First, the method is numerically validated with three-dimensional head models affected by anatomically-realistic strokes. Then, a further assessment through experimental data obtained with a cylindrical phantom is conducted. A quite accurate reconstruction of the variations of dielectric properties inside the patient’s head due to the insurgence of stroke is obtained in both numerical and experimental cases, showing the potentiality of the proposed approach. Full article
(This article belongs to the Special Issue Electromagnetic Imaging from Radio Frequency to Sub-millimeter Waves)
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15 pages, 7521 KB  
Article
A Novel Fluorescent Chemosensor Based on Rhodamine Schiff Base: Synthesis, Photophysical, Computational and Bioimaging Application in Live Cells
by Oyedoyin Aduroja, Roosevelt Shaw, Sisay Uota, Isaac Abiye, James Wachira and Fasil Abebe
Inorganics 2025, 13(1), 5; https://doi.org/10.3390/inorganics13010005 - 27 Dec 2024
Cited by 5 | Viewed by 3002
Abstract
A novel rhodamine-6G derivative RdN was synthesized by condensing rhodamine glyoxal and 3-hydroxy-2-naphthoic hydrazide using a microwave irradiation-assisted reaction. Colorimetric and photophysical studies have demonstrated that the molecule produced can selectively sense Pb2+ and Cu2+ ions in a solution of CH [...] Read more.
A novel rhodamine-6G derivative RdN was synthesized by condensing rhodamine glyoxal and 3-hydroxy-2-naphthoic hydrazide using a microwave irradiation-assisted reaction. Colorimetric and photophysical studies have demonstrated that the molecule produced can selectively sense Pb2+ and Cu2+ ions in a solution of CH3CN/H2O (9:1, v/v). The spirolactam ring of RdN opens upon complexation with the cations, forming a highly fluorescent complex and a visible color change in the solution. The compound RdN was further studied with the help of computational methods such as the Density Functional Theory (DFT) method and time-dependent density theory (TD-DFT) calculations to study the binding interactions and properties of the molecule. DFT calculations and job plot data supported the 2:1 complex formation between RdN and Pb2+/Cu2+. The limit of detection for Pb2+ was determined to be 0.112 µM and 0.130 µM for Cu2+. The probe RdN was applied to the image of Pb2+ and Cu2+ ions in living cells and is safe for biomedical applications. It is used to monitor Pb2+ in environmental water samples. Full article
(This article belongs to the Special Issue Synthesis and Application of Luminescent Materials, 2nd Edition)
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24 pages, 7984 KB  
Article
Design and Implementation of an Ultra-Wideband Water Immersion Antenna for Underwater Ultrasonic Sensing in Microwave-Induced Thermoacoustic Tomography
by Feifei Tan and Haishi Wang
Sensors 2024, 24(19), 6311; https://doi.org/10.3390/s24196311 - 29 Sep 2024
Cited by 1 | Viewed by 2132
Abstract
Microwave-induced thermoacoustic tomography (MITAT) holds significant promise in biomedical applications. It creates images using ultrasonic sensors to detect thermoacoustic signals induced by microwaves. The key to generating thermoacoustic signals that accurately reflect the fact is to achieve sufficient and uniform microwave power absorption [...] Read more.
Microwave-induced thermoacoustic tomography (MITAT) holds significant promise in biomedical applications. It creates images using ultrasonic sensors to detect thermoacoustic signals induced by microwaves. The key to generating thermoacoustic signals that accurately reflect the fact is to achieve sufficient and uniform microwave power absorption of the testing target, which is closely tied to the microwave illumination provided by the antenna. In this article, we introduce a novel design and implementation of an ultra-wideband water immersion antenna for an MITAT system. We analyze and compare the advantages of selecting water as the background medium. Simulations are conducted to analyze the ultra-wideband characteristics in impedance matching, axial ratio, and radiation pattern of the proposed antenna. The measured |S11| shows good agreement with the simulated results. We also simulate the microwave power absorption of tumor and brain tissue, and the uniform microwave power absorption and high contrast between the tumor and brain indicate the excellent performance of the proposed antenna in the MITAT system. Full article
(This article belongs to the Special Issue Advanced Microwave Sensors and Their Applications in Measurement)
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