Search Results (300)

Recent advancements have been made in the precise prediction of protein structures within the Protein Folding Problem (PFP), particularly in relation to minimizing the energy function to achieve stable and biologically relevant protein structures. This problem is classified as NP-hard within computational theory, necessitating the development of various techniques and algorithms. Bio-inspired algorithms have proven effective in addressing NP-hard challenges in practical applications. This study introduces a novel hybrid algorithm, termed GRSABio, which integrates the strategies of Jumping Spider Algorithm (JSOA) with the Golden Ratio Simulated Annealing (GRSA) for peptide prediction. Furthermore, the GRSABio algorithm incorporates a Convolutional Neural Network for fragment prediction (FCNN), forms an enhanced methodology called GRSABio-FCNN. This integrated framework achieves improved structure refinement based on energy for protein prediction. The proposed enhanced GRSABio-FCNN approach was applied to a dataset of 60 peptides. The Wilcoxon and Friedman statistics test were employed to compare the GRSABio-FCNN results against recent state-of-the-art-approaches. The results of these tests indicate that the GRSABio-FCNN approach is competitive with state-of-the-art methods for peptides up to 50 amino acids in length and surpasses leading PFP algorithms for peptides with up to 30 amino acids. Full article

This study presents a novel method for controlling the position and orientation of the bioinspired I-SUPPORT soft robot, which represents a relevant advancement in the field of soft robotics. The approach is based on module actuation decoupling and fractional-order control, offering a more advanced and robust control solution. This innovation enhances the versatility of the robot and illustrates the efficacy of fractional-order controllers, which are comparable to current meta-learning-based controllers. The research involves experiments in both vertical and horizontal configurations, addressing tasks ranging from simple orientation to complex interactions, such as gentle rubbing during bathing activities with the robot. These experimental results exemplify the efficacy of the proposed control strategy and provide a foundation for future research in soft robotics control, underscoring its potential for broader applications and further technological advancement. Full article

Electroless nickel deposition (ELD) is an autocatalytic technique extensively used to impart conductive, protective, and mechanical functionalities to inherently non-conductive synthetic substrates. This review systematically explores the fundamental mechanisms of electroless nickel deposition, emphasising recent advancements in surface activation methods, solvent systems, and microstructural control. Critical analysis reveals that bio-inspired activation methods, such as polydopamine (PDA) and tannic acid (TA), significantly enhance coating adhesion and durability compared to traditional chemical etching and plasma treatments. Additionally, solvent engineering, particularly using polar aprotic solvents like dimethyl sulfoxide (DMSO) and ethanol-based systems, emerges as a key strategy for achieving uniform, dense, and flexible coatings, overcoming limitations associated with traditional aqueous baths. The review also highlights that microstructural tailoring, specifically the development of amorphous-nanocrystalline hybrid nickel coatings, effectively balances mechanical robustness (hardness exceeding 800 HV), flexibility, and corrosion resistance, making these coatings particularly suitable for wearable electronic textiles and smart materials. Furthermore, commercial examples demonstrate the real-world applicability and market readiness of nickel-coated synthetic fibres. Despite significant progress, persistent challenges remain, including reliable long-term adhesion, internal stress management, and environmental sustainability. Future research should prioritise environmentally benign plating baths, standardised surface activation protocols, and scalable deposition processes to fully realise the industrial potential of electroless nickel coatings. Full article

Industrial robots are undergoing a transformative shift as Artificial Intelligence (AI)-driven and bio-inspired control strategies unlock new levels of precision, adaptability, and multi-dimensional sustainability aligned with Industry 5.0 (energy efficiency, material circularity, and life-cycle emissions). This systematic review analyzes 160 peer-reviewed industrial robotics control studies (2023–2025), including an expanded bio-inspired/human-centric subset, to evaluate: (1) the dominant and emerging control methodologies; (2) the transformative role of digital twins and 5G-enabled connectivity; and (3) the persistent technical, ethical, and environmental challenges. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines, the study employs a rigorous methodology, focusing on adaptive control, deep reinforcement learning (DRL), human–robot collaboration (HRC), and quantum-inspired algorithms. The key findings highlight up to 30% latency reductions in real-time optimization, up to 22% efficiency gains through digital twins, and up to 25% energy savings from bio-inspired designs (all percentage ranges are reported relative to the comparator baselines specified in the cited sources). However, critical barriers remain, including scalability limitations (with up to 40% higher computational demands) and cybersecurity vulnerabilities (with up to 20% exposure rates). The convergence of AI, bio-inspired systems, and quantum computing is poised to enable sustainable, autonomous, and human-centric robotics, yet requires standardized safety frameworks and hybrid architectures to fully support the transition from Industry 4.0 to Industry 5.0. This review offers a strategic roadmap for future research and industrial adoption, emphasizing human-centric design, ethical frameworks, and circular-economy principles to address global manufacturing challenges. Full article

In nature, organisms often rely on the integration of local sensory information and prior experience to flexibly adapt to complex and dynamic environments, enabling efficient path selection. This bio-inspired mechanism of perception and behavioral adjustment provides important insights for path planning in mobile robots operating under uncertainty. In recent years, the introduction of deep reinforcement learning (DRL) has empowered mobile robots to autonomously learn navigation strategies through interaction with the environment, allowing them to identify obstacle distributions and perform path planning even in unknown scenarios. To further enhance the adaptability and path planning performance of robots in complex environments, this paper develops a deep reinforcement learning framework based on the Soft Actor–Critic (SAC) algorithm. First, to address the limited adaptability of existing transfer learning methods, we propose an action-level fusion mechanism that dynamically integrates prior and current policies during inference, enabling more flexible knowledge transfer. Second, a bio-inspired radar perception optimization method is introduced, which mimics the biological mechanism of focusing on key regions while ignoring redundant information, thereby enhancing the expressiveness of sensory inputs. Finally, a reward function based on ineffective behavior recognition is designed to reduce unnecessary exploration during training. The proposed method is validated in both the Gazebo simulation environment and real-world scenarios. Experimental results demonstrate that the approach achieves faster convergence and superior obstacle avoidance performance in path planning tasks, exhibiting strong transferability and generalization across various obstacle configurations. Full article

The Adaptive Cross Ivy (ACIVY) algorithm is a novel bio-inspired metaheuristic that emulates ivy plant growth behaviors for complex optimization problems. While the original Ivy Optimization Algorithm (IVYA) demonstrates a competitive performance, it suffers from limited inter-individual information exchange, inadequate directional guidance for local optima escape, and abrupt exploration–exploitation transitions. To address these limitations, ACIVY integrates three strategic enhancements: the crisscross strategy, enabling horizontal and vertical crossover operations for improved population diversity; the LightTrack strategy, incorporating positional memory and repulsion mechanisms for effective local optima escape; and the Top-Guided Adaptive Mutation strategy, implementing ranking-based mutation with dynamic selection pools for smooth exploration–exploitation balance. Comprehensive evaluations on the CEC2017 and CEC2022 benchmark suites demonstrate ACIVY’s superior performance against state-of-the-art algorithms across unimodal, multimodal, hybrid, and composite functions. ACIVY achieved outstanding average rankings of 1.25 (CEC2022) and 1.41 (CEC2017 50D), with statistical significance confirmed through Wilcoxon tests. Practical applications in engineering design optimization and UAV path planning further validate ACIVY’s robust performance, consistently delivering optimal solutions across diverse real-world scenarios. The algorithm’s exceptional convergence precision, solution reliability, and computational efficiency establish it as a powerful tool for challenging optimization problems requiring both accuracy and consistency. Full article

Enhancing the thermal performance of building façades is vital for reducing energy demand in hot desert climates, where envelope heat gain increases cooling loads. This study investigates the integration of biomimicry into opaque ventilated façade (OVF) systems as a novel approach to reduce façade surface temperatures. Thirteen bio-inspired façade configurations, modeled after strategies observed in nature, were evaluated using computational fluid dynamics simulations to assess their effectiveness in increasing airflow and reducing inner skin surface temperatures. Results show that all proposed biomimetic solutions outperformed the baseline OVF in terms of thermal performance, with the wide top mound configuration achieving the greatest temperature reduction—up to 5.9 °C below the baseline OVF and 16.4 °C below an unventilated façade. The study introduces an innovative methodology that derives façade design parameters from nature and validates them through simulation. These findings highlight the potential of nature-based solutions to improve building envelope performance in extreme climates. Full article

Kirigami-inspired geometries offer a lightweight, bioinspired strategy for friction enhancement and anchoring in soft robotics. This study presents a bioinspired kirigami structure designed to enhance the anchoring performance of soft robotic systems through systematic geometric and actuation parameter optimization. Drawing inspiration from the anisotropic friction mechanisms observed in reptilian scales, we integrated linear, triangular, trapezoidal, and hybrid kirigami cuts onto flexible plastic sheets. A compact 12 V linear actuator enabled cyclic actuation via a custom firmware loop, generating controlled buckling and directional friction for effective locomotion. Through experimental trials, we quantified anchoring efficiency using crawling distance and stride metrics across multiple cut densities and actuation conditions. Among the tested configurations, the triangular kirigami with a 4 × 20 unit density on 100 µm PET exhibited the most effective performance, achieving a stride efficiency of approximately 63% and an average crawling speed of ~47 cm/min under optimized autonomous operation. A theoretical framework combining buckling mechanics and directional friction validated the observed trends. This study establishes a compact, tunable anchoring mechanism for soft robotics, offering strong potential for autonomous exploration in constrained environments. Full article

Wall-climbing robots have garnered significant attention for their ability to operate in hazardous environments. Among these, bioinspired gecko robots exhibit exceptional adaptability and climbing performance due to their flexible morphology and intelligent motion strategies. This review systematically analyzes studies published between 2000–2025, sourced from IEEE Xplore, Web of Science, and Scopus databases, to explore the biological principles of gecko adhesion and locomotion. A structured literature review methodology is employed, through which representative climbing robots are systematically categorized based on spine flexibility (rigid vs. flexible) and attachment mechanisms (adhesive, suction, claw-based). We analyze various motion control strategies, from hierarchical architectures to advanced neural algorithms, with a focus on central pattern generator (CPG)-based systems. By synthesizing current research and technological advancements, this paper provides a roadmap for developing more efficient, adaptive, and intelligent wall-climbing robots, addressing key challenges and future directions in the field. Full article

This study presents a systematic literature review on the mathematical modeling of resilient and viable supply chains, grounded in the PRISMA methodology and applied to a curated corpus of 235 peer-reviewed scientific articles published between 2011 and 2025. The search strategy was implemented across four major academic databases (Scopus and Web of Science) using Boolean operators to capture intersections among the core concepts of supply chains, resilience, viability, and advanced optimization techniques. The screening process involved a double manual assessment of titles, abstracts, and full texts, based on inclusion criteria centered on the presence of formal mathematical models, computational approaches, and thematic relevance. As a result of the selection process, six thematic categories were identified, clustering the literature according to their analytical objectives and methodological approaches: viability-oriented modeling, resilient supply chain optimization, agile and digitally enabled supply chains, logistics optimization and network configuration, uncertainty modeling, and immune system-inspired approaches. These categories were validated through a bibliometric analysis and a thematic map that visually represents the density and centrality of core research topics. Descriptive analysis revealed a significant increase in scientific output starting in 2020, driven by post-pandemic concerns and the accelerated digitalization of logistics operations. At the methodological level, a high degree of diversity in modeling techniques was observed, with an emphasis on mixed-integer linear programming (MILP), robust optimization, multi-objective modeling, and the increasing use of bio-inspired algorithms, artificial intelligence, and simulation frameworks. The results confirm a paradigm shift toward integrative frameworks that combine robustness, adaptability, and Industry 4.0 technologies, as well as a growing interest in biological metaphors applied to resilient system design. Finally, the review identifies research gaps related to the formal integration of viability under disruptive scenarios, the operationalization of immune-inspired models in logistics environments, and the need for hybrid approaches that jointly address resilience, agility, and sustainability. Full article

This paper introduces a novel bio-inspired metaheuristic algorithm, named the sharpbelly fish optimizer (SFO), inspired by the collective ecological behaviors of the sharpbelly fish. The algorithm integrates four biologically motivated strategies—(1) fitness-driven fast swimming, (2) convergence-guided gathering, (3) stagnation-triggered dispersal, and (4) disturbance-induced escape—which synergistically enhance the balance between global exploration and local exploitation. To assess its performance, the proposed SFO is evaluated on the CEC2022 benchmark suite under various dimensions. The experimental results demonstrate that SFO consistently achieves competitive or superior optimization accuracy and convergence speed compared to seven state-of-the-art metaheuristic algorithms. Furthermore, the algorithm is applied to three classical constrained engineering design problems: pressure vessel, speed reducer, and gear train design. In these applications, SFO exhibits strong robustness and solution quality, validating its potential as a general-purpose optimization tool for complex real-world problems. These findings highlight SFO’s effectiveness in tackling nonlinear, constrained, and multimodal optimization tasks, with promising applicability in diverse engineering scenarios. Full article

Background: Vaccines have revolutionized disease prevention, yet their effectiveness is challenged by variable immunogenicity, individual response differences, and emerging variants. Biomimetic strategies, inspired by natural immune processes, offer new avenues to enhance vaccine performance. Objectives: This narrative review examines how bioinspired approaches—grounded in evolutionary medicine, immunology, and host–microbiota interactions—can improve vaccine immunogenicity and long-term protection. We further examine the evolutionary foundations of immune responses, highlighting how an evolutionary perspective can inform the development of durable, broadly protective, and personalized vaccines. Furthermore, mechanistic insights at the molecular and cellular level are explored, including Toll-like receptor (TLR) engagement, dendritic cell activation pathways, and MHC-I/MHC-II-mediated antigen presentation. These mechanisms are often mimicked in biomimetic systems to enhance uptake, processing, and adaptive immune activation. Results: The review highlights how immunosenescence, maternal immunity, genetic variation, and gut microbiota composition influence vaccine responses. Biomimetic platforms—such as nanoparticle carriers and novel adjuvants—enhance antigen presentation, boost adaptive immunity, and may overcome limitations in traditional vaccine approaches. Additionally, co-administration strategies, delivery systems, and microbiota-derived immunomodulators show promise in improving vaccine responsiveness. Conclusions: Integrating biomimetic and evolutionary principles into vaccine design represents a promising path toward safer, longer-lasting, and more effective immunizations Full article

Bioinspired morphing offers a powerful route to higher aerodynamic and hydrodynamic efficiency. Birds reposition feathers, bats extend compliant membrane wings, and fish modulate fin stiffness, tailoring lift, drag, and thrust in real time. To capture these advantages, engineers are developing airfoils, rotor blades, and hydrofoils that actively change shape, reducing drag, improving maneuverability, and harvesting energy from unsteady flows. This review surveys over 296 studies, with primary emphasis on literature published between 2015 and 2025, distilling four biological archetypes—avian wing morphing, bat-wing elasticity, fish-fin compliance, and tubercled marine flippers—and tracing their translation into morphing aircraft, ornithopters, rotorcraft, unmanned aerial vehicles, and tidal or wave-energy converters. We compare experimental demonstrations and numerical simulations, identify consensus performance gains (up to 30% increase in lift-to-drag ratio, 4 dB noise reduction, and 15% boost in propulsive or power-capture efficiency), and analyze materials, actuation, control strategies, certification, and durability as the main barriers to deployment. Advances in multifunctional composites, electroactive polymers, and model-based adaptive control have moved prototypes from laboratory proof-of-concept toward field testing. Continued collaboration among biology, materials science, control engineering, and fluid dynamics is essential to unlock robust, scalable morphing technologies that meet future efficiency and sustainability targets. Full article

Background: Biomimetic strategies have gained increasing attention for their ability to enhance the delivery, stability, and functionality of nutraceuticals by emulating natural biological systems. However, the literature remains fragmented, often focusing on isolated technologies without integrating regulatory, predictive, or translational perspectives. Objective: This review aims to provide a comprehensive and multidisciplinary synthesis of biomimetic and bio-inspired nanocarrier strategies for nutraceutical delivery, while identifying critical gaps in standardization, scalability, and clinical translation. Results: We present a structured classification matrix that maps biomimetic delivery systems by material type, target site, and bioactive compound class. In addition, we analyze predictive design tools (e.g., PBPK modeling and AI-based formulation), regulatory frameworks (e.g., EFSA, FDA, and GSRS), and risk-driven strategies as underexplored levers to accelerate innovation. The review also integrates ethical and environmental considerations, and highlights emerging trends such as multifunctional hybrid systems and green synthesis routes. Conclusions: By bridging scientific, technological, and regulatory domains, this review offers a novel conceptual and translational roadmap to guide the next generation of biomimetic nutraceutical delivery systems. It addresses key bottlenecks and proposes integrative strategies to enhance design precision, safety, and scalability. Full article

This paper presents a comprehensive review of multimodal emotion recognition (MER), a process that integrates multiple data modalities such as speech, visual, and text to identify human emotions. Grounded in biomimetics, the survey frames MER as a bio-inspired sensing paradigm that emulates the way humans seamlessly fuse multisensory cues to communicate affect, thereby transferring principles from living systems to engineered solutions. By leveraging various modalities, MER systems offer a richer and more robust analysis of emotional states compared to unimodal approaches. The review covers the general structure of MER systems, feature extraction techniques, and multimodal information fusion strategies, highlighting key advancements and milestones. Additionally, it addresses the research challenges and open issues in MER, including lightweight models, cross-corpus generalizability, and the incorporation of additional modalities. The paper concludes by discussing future directions aimed at improving the accuracy, explainability, and practicality of MER systems for real-world applications. Full article