Biomimetic Approaches in Healthcare—Innovations Inspired by Nature: 3rd Edition

A special issue of Biomimetics (ISSN 2313-7673). This special issue belongs to the section "Development of Biomimetic Methodology".

Deadline for manuscript submissions: 15 February 2026 | Viewed by 572

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Faculty of Sports Sciences, Universidad Europea de Madrid, 28670 Madrid, Spain
Interests: child stress; physiology; psychology; nutrition; health; disease; environment
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Special Issue Information

Dear Colleagues,

This Special Issue, ‘Biomimetic Approaches in Healthcare—Innovations Inspired by Nature: 3rd Edition’, explores the innovative intersection of healthcare and nature-inspired solutions. This Special Issue will delve into the emerging field of biomimetics, where scientists and healthcare professionals draw inspiration from the natural world to develop groundbreaking healthcare technologies and strategies. By mimicking biological processes, structures, and systems found in the environment, researchers aim to create effective and sustainable solutions for healthcare challenges. This Special Issue will feature contributions that showcase how biomimetic approaches are revolutionizing medical diagnostics, treatment modalities, and healthcare practices. From bio-inspired materials for regenerative medicine to nature-inspired algorithms for healthcare data analysis, this Special Issue will highlight the diverse applications of biomimetics in improving healthcare outcomes.

Prof. Dr. Vicente Javier Clemente-Suárez
Prof. Dr. Ana Isabel Beltrán-Velasco
Guest Editors

Manuscript Submission Information

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Keywords

  • biomimetics
  • healthcare innovations
  • nature-inspired solutions
  • medical diagnostics
  • regenerative medicine
  • bio-inspired materials
  • healthcare data analysis
  • natural algorithms
  • biologically inspired technology
  • sustainable healthcare

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Published Papers (1 paper)

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Review

43 pages, 1468 KiB  
Review
Biometric Strategies to Improve Vaccine Immunogenicity and Effectiveness
by Vicente Javier Clemente-Suárez, Laura Redondo-Flórez, Alvaro Bustamante-Sánchez, Alexandra Martín-Rodríguez, Rodrigo Yáñez-Sepúlveda and Jose Francisco Tornero-Aguilera
Biomimetics 2025, 10(7), 439; https://doi.org/10.3390/biomimetics10070439 - 3 Jul 2025
Viewed by 495
Abstract
Background: Vaccines have revolutionized disease prevention, yet their effectiveness is challenged by variable immunogenicity, individual response differences, and emerging variants. Biomimetic strategies, inspired by natural immune processes, offer new avenues to enhance vaccine performance. Objectives: This narrative review examines how bioinspired approaches—grounded in [...] Read more.
Background: Vaccines have revolutionized disease prevention, yet their effectiveness is challenged by variable immunogenicity, individual response differences, and emerging variants. Biomimetic strategies, inspired by natural immune processes, offer new avenues to enhance vaccine performance. Objectives: This narrative review examines how bioinspired approaches—grounded in evolutionary medicine, immunology, and host–microbiota interactions—can improve vaccine immunogenicity and long-term protection. We further examine the evolutionary foundations of immune responses, highlighting how an evolutionary perspective can inform the development of durable, broadly protective, and personalized vaccines. Furthermore, mechanistic insights at the molecular and cellular level are explored, including Toll-like receptor (TLR) engagement, dendritic cell activation pathways, and MHC-I/MHC-II-mediated antigen presentation. These mechanisms are often mimicked in biomimetic systems to enhance uptake, processing, and adaptive immune activation. Results: The review highlights how immunosenescence, maternal immunity, genetic variation, and gut microbiota composition influence vaccine responses. Biomimetic platforms—such as nanoparticle carriers and novel adjuvants—enhance antigen presentation, boost adaptive immunity, and may overcome limitations in traditional vaccine approaches. Additionally, co-administration strategies, delivery systems, and microbiota-derived immunomodulators show promise in improving vaccine responsiveness. Conclusions: Integrating biomimetic and evolutionary principles into vaccine design represents a promising path toward safer, longer-lasting, and more effective immunizations Full article
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