Search Results (116)

Cervical spondylosis is a common cause of spinal cord dysfunction, and anterior cervical discectomy and fusion (ACDF) is widely employed when conservative treatment fails. Conventional implant systems such as the cervical cage with plate (CCP) and zero-profile stand-alone cage (ZPSC) are commonly used to enhance spinal stability and promote fusion, but they are associated with complications including dysphagia and adjacent segment degeneration. To address these limitations, a novel flexible plate cage system (FPCS) has been developed to optimize biomechanical performance while minimizing surgical risk. In this study, a finite element model of the C3–T1 cervical spine was constructed to simulate ACDF at the C5–C6 level using CCP, ZPSC, and FPCS implants. Under standardized loading conditions, von Mises stress was analyzed in the bone, intervertebral disc, endplates, cage, and screws, using the mean of the top 5% stress values to ensure accuracy. All surgical models showed increased stress compared to the intact reference spine. The ZPSC model exhibited the highest stress in the cage and screws, suggesting a more concentrated load path. The CCP model showed a more evenly distributed stress profile, particularly affecting the inferior adjacent segment. The FPCS model demonstrated moderate cage stress, reduced screw stress, and the highest plate stress, indicating a design that effectively redirects mechanical load from the screw-bone interface toward the anterior plate. This may be related to the unique structural configuration of the FPCS, which secures screws horizontally into the anterior vertebral body without penetrating the endplates. These findings suggest that the FPCS may offer a biomechanically favorable alternative to existing ACDF implants. Full article

Material-extrusion (MEX) printing with automated filament switching enables single-build multi-material laminates, but interfaces between dissimilar polymers may govern failure. Here, monolithic PETG, monolithic PC–ABS, and an alternating PETG/PC–ABS laminate (COMP) with 0.2 mm laminae (4 mm total) were fabricated and benchmarked. Tensile behavior was measured using ISO 527-2 Type 1B specimens at 5 and 50 mm/min, complemented by three-point bending in horizontal/vertical orientations, unnotched Charpy impact (ISO 179), Shore D hardness (ISO 868), and SEM fractography. COMP delivered the highest horizontal flexural strength (159.82 ± 25.42 MPa), exceeding both single-material baselines, indicating improved bending load capacity in the preferred orientation. In Charpy impact, COMP absorbed more energy than PETG in the horizontal condition (0.86 ± 0.14 J vs. 0.57 ± 0.06 J) but remained below PC–ABS. In tension, COMP strength decreased by ~21–23% relative to PETG and by ~5–6% relative to PC–ABS at both speeds, consistent with interface-controlled damage. SEM revealed void-assisted crack initiation and interfacial debonding aligned with raster paths, highlighting interfacial strengthening and porosity reduction as key routes to improve tensile performance while retaining favorable flexural and impact response. Full article

The surface decoration techniques, such as incising-filling, glaze spraying, wood firing, and secondary low-temperature refiring, etc., have been widely used for traditional potteries, such as Jianshui purple pottery. These surface modifications are mainly for artistic expression, whereas functional surface modification has barely been reported. The development of novel coating materials and processes is an alternative path for the innovation of traditional pottery. However, the surface functional materials often peel or detach from the pottery body after high-temperature sintering. It is thus imperative to develop coating materials and processes with robust adhesion and accommodation for secondary functional materials. Through the screening of different ZrO(OH)₂ sols and coating processes, the coating of ZrO(OH)₂ sol on the 800 °C baked Jianshui purple pottery achieved uniform and tight surface coating. Reducing the colloidal particle size and particle concentration in the sol, as well as Y³⁺ doping, is also conductive to the structural stability of the coatings. Additional loading of silver nanoparticles onto the ZrO₂ coating layer effectively endows the pottery with antibacterial performance. The coated samples loaded with silver nanoparticles exhibited an antibacterial rate of 32.7% after accelerated desorption, demonstrating potential for functional pottery applications. Full article

This study aimed to systematically optimize the fermentation process for xylanase production by Aspergillus tubingensis FS7Y52, elucidate its enzymatic properties, and evaluate its application potential in the biodegradation of agricultural wastes. Key influencing factors were initially identified through single-factor experiments, followed by the screening of significant factors using the Plackett–Burman design. The optimal values were then approached employing the steepest ascent path method and Response Surface Methodology. The final determined optimal fermentation conditions were: corn husk (20–40 mesh) 40 g/L, tryptone 13.7 g/L, Tween-20 0.75 g/L, pH 6.5, fermentation temperature 42.1 °C, fermentation time 2 days, shaking speed 140 rpm, inoculum size 1 × 10⁷ spores/30 mL, and liquid loading volume 30 mL/250 mL. Under these conditions, xylanase activity reached 115.23 U/mL, representing a significant increase of 90.7% compared to pre-optimization levels. Studies on enzymatic properties revealed that the enzyme exhibited maximum activity at pH 5.0 and 55 °C, and demonstrated good stability within the pH range of 4.5–7.0 and at temperatures below 50 °C. In the degradation of agricultural waste, the enzyme system produced by this strain exhibits significant degradation effects on agricultural waste. A pronounced additive effect exists between xylanase and cellulase. When the dosages were 2430 U/g and 15.7 U/g for xylanase and cellulase, respectively, the maximum reducing sugar release reached 23.3%. The degradation rates of cellulose, hemicellulose, and lignin reached 57.8%, 51.9%, and 55.0%, respectively. Additionally, the strain itself exhibits significant degradation effects on substances such as cellulose in agricultural waste, achieving degradation rates of 78.8%, 70.8%, and 52.5% for cellulose, hemicellulose, and lignin, respectively. This study provides a solid theoretical foundation and technical support for the efficient production of xylanase by A. tubingensis and its industrial application in the resource utilization of agricultural wastes. From an economic perspective, the optimized strategy significantly enhances enzyme production efficiency while reducing substrate consumption and operational costs per unit of enzyme produced. This makes the resulting enzyme mixture more economically viable for large-scale applications. The utilization of this enzyme system to convert tobacco stems into sugars represents a compelling case for agricultural wastes reuse. It transforms residual biomass into high-value products, contributing to a circular bioeconomy by reducing waste and creating new renewable alternatives to conventional products. It provides an economically viable solution for the high-value utilization of woody lignocellulosic biomass. Full article

While multi-view visualization systems are widely used for mining vehicle teleoperation, they often impose high cognitive load and restrict operator attention. To explore a more efficient alternative, this study evaluated a merged-view interface that integrates multiple camera perspectives into a single coherent display. In a controlled experiment, 35 participants navigated a teleoperated robot along a 50 m lab-scale path representative of an underground mine under both multi-view and merged-view conditions. Task performance and eye-tracking data—including completion time, path adherence, and speed-limit violations—were collected for comparison. The merged-view system enabled 6% faster completion times, 21% higher path adherence, and 28% fewer speed-limit violations. Eye-tracking metrics indicated more efficient and distributed attention: blink rate decreased by 29%, fixation duration shortened by 18%, saccade amplitude increased by 11%, and normalized gaze-transition entropy rose by 14%, reflecting broader and more adaptive scanning. NASA-TLX scores further showed a 27% reduction in perceived workload. Regression-based sensitivity analysis revealed that gaze entropy was the strongest predictor of efficiency in the multi-view condition, while fixation duration dominated under merged-view visualization. For path adherence, blink rate was most influential in the multi-view setup, whereas fixation duration became key in merged-view operation. Overall, the results indicated that merged-view visualization improved visual attention distribution and reduced cognitive tunneling indicators in a controlled laboratory teleoperation task, offering early-stage, interface-level insights motivated by mining-relevant teleoperation challenges. Full article

To improve the continuous chordwise bending performance of morphing wings, this study proposes a rigid–flexible coupled wing rib structure and its control strategy. Initially, the optimal rigid–flexible hybrid configuration was optimized via the mean camber line parameterization and genetic algorithm. For the flexible segment, topology optimization was conducted using the load path method, followed by subspace-based shape–size alternating optimization; bionic “longbow” curved beams and ‘S’-shaped substructures were adopted to enhance deformability. Biomimetic pneumatic muscles were used as actuators, and a fuzzy-adjusted PI sliding mode controller was designed to address the issue that traditional PI sliding mode controllers cannot achieve precise control under non-optimal parameters or when there is a significant difference in deformation targets. Experimental results show that when the flexible rib deflects by 15°, the three-rib wing box achieves a 30° deflection, with stresses within the allowable limit of 7075Al-T6 (540 MPa) and a deformation error of only 7.6%. For the 15° downward bending control, the adjustment time is 6.06 s, the steady-state error is 0.19°, and the overshoot is 1.8%. This study verifies the feasibility of the proposed rigid–flexible coupled structure and fuzzy PI-SMC, providing a technical reference for morphing aircraft. Full article

To prevent swine fever transmission, swine farms in China adopt enclosed management, making strict farm personnel biosecurity essential for minimizing the risk of pathogen introduction. However, current shower-in procedures and personnel movement records on many farms still rely on manual logging, which is prone to omissions and cannot support enterprise-level supervision. To address these limitations, this study develops a digital personnel management system designed specifically for the changing-room environment that forms the core biosecurity barrier. The proposed three-tier architecture integrates distributed identification terminals, local central controllers, and a cloud-based data platform. The system ensures reliable identity verification, synchronizes templates across terminals, and maintains continuous data availability, even in unstable network conditions. Fingerprint-based identity validation and a lightweight CAN-based communication mechanism were implemented to ensure robust operation in electrically noisy livestock facilities. System performance was evaluated through recognition tests, multi-frame template transmission experiments, and high-load CAN/MQTT communication tests. The system achieved a 91.4% overall verification success rate, lossless transmission of multi-frame fingerprint templates, and stable end-to-end communication, with mean CAN-bus processing delays of 99.96 ms and cloud-processing delays below 70.7 ms. These results demonstrate that the proposed system provides a reliable digital alternative to manual personnel movement records and shower duration, offering a scalable foundation for biosecurity supervision. While the present implementation focuses on identity verification, data synchronization, and calculating shower duration based on the interval between check-ins, the system architecture can be extended to support movement path enforcement and integration with wider biosecurity infrastructures. Full article

Drone photogrammetry and per-step spatial analysis were used to re-evaluate the West Gold Hill Dinosaur Tracksite (Bluff Sandstone, Colorado), which preserves an exceptionally long sauropod pes trackway. Building on earlier segment-based descriptions, we reconstructed the entire succession at millimetre-level resolution and quantified turning and gait asymmetry within an integrated digital workflow (UAV photogrammetry, Blender-based landmarking, scripted analysis). Of 134 footprints previously reported, 131 were confidently identified along a mapped path of 95.489 m that records 340° cumulative anticlockwise reorientation. Traditional end-point tortuosity (direct distance/trackway length; DL/TL) yields a moderate ratio of 0.462, whereas our incremental analysis isolates a fully looped subsection (tracks 38–83) with tortuosity of 0.0001 (DL 0.005 m; TL 34.825 m), revealing extreme local curvature that global (end-to-end) measures dilute. Gauge varies substantially along the trackway: the traditional metric (single pes width) averages 32.2% (wide gauge) with numerous medium-gauge representatives, while footprint-specific (‘incremental’) gauge spans 23.1–71.0% (narrow/medium/wide gauges observed within the same trackway). Our tests for asymmetry quantified that left-to-right paces and steps are longer (p = 0.001 and 0.008, respectively), central trackway width is greater (p = 0.043), and pace angulation is lower (p = 0.040) than right-to-left. Behaviourally, these signals are consistent with right-side load-avoidance but remain speculative (alternative explanations may include habitual laterality, local substrate heterogeneity). The study demonstrates how UAV-enabled, fully digital, sequential analyses can recover intra-trackway variability and enhance behavioural understanding of extinct trackmakers from fossil trackways. Full article

Surplus out-of-spec Al powders, typically discarded, remain an underused resource. Their reuse via alternative consolidation routes is a sustainable path for AlSi10Mg alloy recycling, but studies on the feasibility of such routes remain scarce. This study proposes a novel route combining powder compaction (under 50 kN and 80 kN loads) and remelting/solidification via suction casting to assess the feasibility of producing dense parts with enhanced properties. Microstructure, mechanical properties (compression and Vickers microhardness), and tribological performance (ball-crater wear under dry and abrasive conditions) were evaluated. The proposed route produced dense AlSi10Mg parts with low porosity levels (≤0.2%) and refined dendritic microstructures (spacing between 2.4 and 4.6 µm). Increased cooling rates promoted microstructural refinement, while higher compaction loads improved densification. The refined microstructure samples achieved compressive strengths above 500 MPa. Remarkably, microstructural refinement led to significantly increased hardness, with values reaching ≥100 HV. The samples compacted at 50 kN and subjected to the highest cooling rate exhibited the lowest dry wear rate (2.3 × 10⁻⁴ mm³/N·m), comparable to additively manufactured AlSi10Mg (AM) samples, confirming the efficiency of this recycling route. The dry wear rates ranged from 2.3 to 3.9 × 10⁻⁴ mm³/N·m, reinforcing the inverse correlation between hardness and dry wear performance. Although abrasive wear resulted in a material loss approximately 3 times higher than dry wear, it preserved the same microstructural dependence: finer, harder, and denser samples exhibited better wear resistance. Full article

This paper explores methods of simulating the behaviour of building structures under progressive collapse conditions through alternative models of different levels of structural idealization. Such models have been applied in many previous studies, but there is insufficient information regarding their reliability and their ability to represent actual structural behaviour as the level of idealization is reduced. To address this, the study adopts the alternative load path method through the well-established concept of notional column removal, performed via nonlinear static analyses of models with different levels of structural idealization. The focus is on the interaction between the directly affected structural members and the surrounding structure, which is shown to significantly influence the overall response under progressive collapse. The results demonstrate that this interaction depends on multiple factors and cannot be reliably captured when the surrounding structure is not explicitly modelled. Building on this finding, the study systematically evaluates how reduced models can be enhanced to better represent these interactions and proposes strategies for defining boundary conditions that preserve global structural behaviour. Overall, the study advances understanding of model idealization effects and provides practical guidance for developing efficient reduced models for progressive collapse simulations without compromising essential aspects of structural response. Full article

This study presents a Digital Image Correlation (DIC)-based experimental framework for the calibration of the Hosford-Coulomb (HC) and Modified-Mohr Coulomb (MMC) damage initiation criteria in an Advanced High Strength Steel (AHSS) DP1000. Three characteristic loading conditions in sheet metal forming—pure shear, uniaxial tension, and plane strain tension—were reproduced using flat specimens in a universal tensile testing machine, thus eliminating the need for costly and time-consuming tooling systems. An additional notch tension specimen was employed to validate the stress-state sensitivity of the proposed calibration approach. By integrating full-field strain data from DIC with tensile test results, stress–strain relationships were directly obtained without finite element modeling. The results confirm the effectiveness of dogbone, mini shear, and plane strain tension specimens in achieving proportional loading path histories up to fracture initiation, with constant stress state evolution during deformation. Comparison of the HC and MMC damage criteria reveals similar fracture loci, with the HC model exhibiting slightly higher resistance between shear and uniaxial tension conditions. This study discusses the suitability of a fully experimental DIC-based methodology for the calibration of stress-state-dependent damage initiation criteria. The results highlight the ability of the proposed methodology as a simplified and lower time-consuming alternative to traditional numerical assisted frameworks. Full article

Attention and brain focus are essential in human activities that require learning. In higher education, a popular means of acquiring knowledge and information is through serious games. The need for integrating digital learning tools, including serious games, into university curricula has been demonstrated by the students’ preferences that are oriented more towards engaging and interactive alternatives than traditional education. This study examines real-time attention measurement in serious games using wearable brain–computer interfaces (BCIs). By capturing electroencephalography (EEG) signals non-invasively, the system continuously monitors players’ cognitive states to assess attention levels during gameplay. The novel approach proposes adaptive attention measurements to investigate the ability to maintain attention during cognitive tasks of different durations and intensities, using a single-channel EEG system—NeuroSky Mindwave Mobile 2. The measures have been achieved on ten volunteer master’s students in Computer Science. Attention levels during short and intense tasks were compared with those recorded during moderate and long-term activities like watching an educational lecture. The aim was to highlight differences in mental concentration and consistency depending on the type of cognitive task. The experiment was designed following a unique protocol applied to all ten students. Data were acquired using the NeuroExperimenter software 6.6, and analytics were performed in RStudio Desktop for Windows 11. Data is available at request for further investigations and analytics. Experimental results demonstrate that wearable BCIs can reliably detect attention fluctuations and that integrating this neuroadaptive feedback significantly enhances player focus and immersion. Thus, integrating real-time cognitive monitoring in serious game design is an efficient method to optimize cognitive load and create personalized, engaging, and effective learning or training experiences. Beta and attention brain waves, associated with concentration and mental processing, had higher values during the gameplay phase than in the lecture phase. At the same time, there are significant differences between participants—some react better to reading, while others react better to interactive games. The outcomes of this study contribute to the design of personalized learning experiences by customizing learning paths. Integrating NeuroSky or similar EEG tools can be a significant step toward more data-driven, learner-aware environments when designing or evaluating educational games. Full article

Planetary gearbox serves as a key transmission component in planetary ball screw actuator systems. Under the action of alternating loads, the stress concentration locations of the planet carrier in actuators with planetary gear trains are prone to fatigue cracks, which can lead to catastrophic system breakdowns. However, due to the complex vibration transmission path and the interference of uninterested vibration components, the characteristic modulation signal is ambiguous, so it is challenging to diagnose this fault. Therefore, this paper proposes a new fault diagnosis method. Firstly, a vibration signal model is established to accurately characterize the amplitude and phase modulation effects caused by cracked carriers, providing theoretical guidance for fault feature identification. Subsequently, three novel sideband evaluators of the modulation signal bispectrum (MSB) and their parameter selection ranges are proposed to efficiently locate the optimal fault-related bifrequency signatures and reduce computational cost, leveraging the effects identified by the model. Finally, a novel health indicator, the mean absolute root value (MARV), is used to monitor the state of the planet carrier. The effectiveness of this method is verified by experiments on the planetary gearbox test rig. The results show that the robustness of the amplitude and phase modulation effect of the cracked carrier in the low-frequency band is significantly higher than that in the high-frequency band, and the initial carrier crack can be accurately identified using this phenomenon under different operating conditions. This study provides a reliable solution for the condition monitoring and health management of the actuation system, which is helpful to improve the safety and reliability of operation. Full article

Short-form video platforms have shifted advertising from standalone, time-bounded spots to feed-embedded, swipeable stimuli, creating a high-velocity processing context that can penalize casting complexity. We ask whether a “one face, many roles” casting strategy (a single actor playing multiple characters) outperforms multi-actor executions, and why. A two-phase pretest (N = 3500) calibrated a realistic ceiling for “multi-actor” casts, then four experiments (total N = 4513) tested mechanisms, boundary conditions, and alternatives. Study 1 (online and offline replications) shows that single-actor ads lower cognitive load and boost account evaluations and purchase intention. Study 2, a field experiment, demonstrates that Need for Closure amplifies these gains via reduced cognitive load. Study 3 documents brand-type congruence: one actor performs better for entertaining/exciting brands, whereas multi-actor suits professional/competence-oriented brands. Study 4 rules out cost-frugality and sympathy using a budget cue and a sequential alternative path (perceived cost constraint → sympathy). Across studies, a chain mediation holds: single-actor casting reduces cognitive load, which elevates brand authenticity and increases purchase intention; a simple mediation links cognitive load to account evaluations. Effects are robust across settings and participant gender. We theorize short-form advertising as a context-embedded persuasion episode that connects information-processing efficiency to authenticity inferences, and we derive practical guidance for talent selection and script design in short-form campaigns. Full article

Cancer remains a major global health concern, and thus, there is a growing demand for efficient and selective therapies with low systemic toxicity. Natural bioactive compounds have emerged as promising alternatives, and terpenoids have shown notable anticancer properties. They exert antiproliferative, proapoptotic, anti-invasive, and antimetastatic effects through the regulation of multiple molecular targets and signaling pathways, including modulation of apoptosis, suppression of angiogenesis, and inhibition of tumor-promoting inflammation. However, their clinical translation is constrained by poor aqueous solubility, low bioavailability, rapid systemic clearance, and inadequate tumor accumulation. Recent advances in nanotechnology offer strategies to overcome these limitations. Nanocarrier-based systems improve the solubility, stability, and pharmacokinetics of terpenoids, while enabling tumor-targeted delivery and controlled release. Various strategies, such as enhanced permeability and retention effect, ligand-mediated active targeting, and stimuli-responsive release have been used to achieve selective tumor accumulation and improved therapeutic outcomes. The purpose of this review is to provide a comprehensive evaluation of nanoformulated terpenoids in cancer with a special emphasis on their therapeutic applications and mechanisms of action. Preclinical studies demonstrate that nanocarrier-loaded terpenoids significantly increase bioavailability, enhance apoptosis, and suppress tumor angiogenesis compared with free terpenoids. The incorporation of artificial intelligence and machine learning further holds promise for the rational design of nanomedicines, accelerating their path toward clinical translation. Collectively, these developments position nanoformulated terpenoids as a powerful platform in precision oncology with strong potential for future application in cancer therapy. Full article