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23 pages, 3418 KiB  
Article
Fog-Enabled Machine Learning Approaches for Weather Prediction in IoT Systems: A Case Study
by Buket İşler, Şükrü Mustafa Kaya and Fahreddin Raşit Kılıç
Sensors 2025, 25(13), 4070; https://doi.org/10.3390/s25134070 - 30 Jun 2025
Viewed by 434
Abstract
Temperature forecasting is critical for public safety, environmental risk management, and energy conservation. However, reliable forecasting becomes challenging in regions where governmental institutions lack adequate measurement infrastructure. To address this limitation, the present study aims to improve temperature forecasting by collecting temperature, pressure, [...] Read more.
Temperature forecasting is critical for public safety, environmental risk management, and energy conservation. However, reliable forecasting becomes challenging in regions where governmental institutions lack adequate measurement infrastructure. To address this limitation, the present study aims to improve temperature forecasting by collecting temperature, pressure, and humidity data through IoT sensor networks. The study further seeks to identify the most effective method for the real-time processing of large-scale datasets generated by sensor measurements and to ensure data reliability. The collected data were pre-processed using Discrete Wavelet Transform (DWT) to extract essential features and reduce noise. Subsequently, three wavelet-processed deep-learning models were employed: Wavelet-processed Artificial Neural Networks (W-ANN), Wavelet-processed Long Short-Term Memory Networks (W-LSTM), and Wavelet-processed Bidirectional Long Short-Term Memory Networks (W-BiLSTM). Among these, the W-BiLSTM model yielded the highest performance, achieving a test accuracy of 97% and a Mean Absolute Percentage Error (MAPE) of 2%. It significantly outperformed the W-LSTM and W-ANN models in predictive accuracy. Forecasts were validated using data obtained from the Turkish State Meteorological Service (TSMS), yielding a 94% concordance, thereby confirming the robustness of the proposed approach. The findings demonstrate that the W-BiLSTM-based model enables reliable temperature forecasting, even in regions with insufficient governmental measurement infrastructure. Accordingly, this approach holds considerable potential for supporting data-driven decision-making in environmental risk management and energy conservation. Full article
(This article belongs to the Section Internet of Things)
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11 pages, 1602 KiB  
Article
Evaluating Assistive Technology Outcomes in Boccia Athletes with Disabilities Using AI-Based Kinematic Analysis
by Wann-Yun Shieh, Yan-Ying Ju, Shiu-Yuan Yang, I-Chun Chen and Hsin-Yi Kathy Cheng
Bioengineering 2025, 12(7), 684; https://doi.org/10.3390/bioengineering12070684 - 23 Jun 2025
Viewed by 397
Abstract
This study explores how artificial intelligence (AI) can support the evaluation of assistive technology outcomes in adaptive sports, focusing on elite boccia athletes with disabilities. Using a multi-stage motion analysis framework, we integrated OpenPose, ViTPose, and Lifting to estimate seated joint kinematics with [...] Read more.
This study explores how artificial intelligence (AI) can support the evaluation of assistive technology outcomes in adaptive sports, focusing on elite boccia athletes with disabilities. Using a multi-stage motion analysis framework, we integrated OpenPose, ViTPose, and Lifting to estimate seated joint kinematics with greater precision. Match footage from 12 athletes at the 2018 Asia-Pacific Boccia Open was analyzed across five biomechanical phases: preparation, acceleration, peak, release, and follow-through. AI-enhanced 2D and 3D pose estimation methods were applied to assess throwing strategies and motor variability. ViTPose outperformed OpenPose in joint detection accuracy (F1-score: 85% vs. 79.5%), while Lifting improved 3D estimation by reducing joint position error by 16%. Principal Component Analysis revealed greater movement consistency in overhand throws compared to underhand techniques. The proposed pipeline provides an interpretable and scalable method for measuring performance, motor control, and strategy-specific movement outcomes in boccia, offering practical applications for evidence-based coaching, athlete classification, and the design of inclusive assistive sport technologies. Full article
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18 pages, 4697 KiB  
Article
Developing a Swallow-State Monitoring System Using Nasal Airflow, Surface Electromyography, and Thyroid Cartilage Movement Detection
by Wann-Yun Shieh, Mohammad Anwar Khan and Ya-Cheng Shieh
Bioengineering 2024, 11(7), 721; https://doi.org/10.3390/bioengineering11070721 - 16 Jul 2024
Cited by 2 | Viewed by 1576
Abstract
The safe ingestion of food and water requires appropriate coordination between the respiratory and swallowing pathways. This coordination can be disrupted because of aging or various diseases, thereby resulting in swallowing disorders. No comparative research has been conducted on methods for effectively screening [...] Read more.
The safe ingestion of food and water requires appropriate coordination between the respiratory and swallowing pathways. This coordination can be disrupted because of aging or various diseases, thereby resulting in swallowing disorders. No comparative research has been conducted on methods for effectively screening swallowing disorders in individuals and providing timely alerts to their caregivers. Therefore, the present study developed a monitoring and alert system for swallowing disorders by using three types of noninvasive sensors, namely those measuring nasal airflow, surface electromyography signals, and thyroid cartilage movement. Two groups of participants, one comprising healthy individuals (58 participants; mean age 49.4 years) and another consisting of individuals with a history of unilateral stroke (21 participants; mean age 54.4 years), were monitored when they swallowed five volumes of water. Through an analysis of the data from both groups, seven indicators of swallowing disorders were identified, and the proposed system characterized the individual’s swallowing state as having a green (safe), yellow (unsafe), or red (highly unsafe) status on the basis of these indicators. The results indicated that the symptoms of swallowing disorders are detectable. Healthcare professionals can then use these data to conduct assessments, perform screening, and provide nutrient intake suggestions. Full article
(This article belongs to the Section Biosignal Processing)
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13 pages, 1048 KiB  
Article
Using an Interpretable Amino Acid-Based Machine Learning Method to Enhance the Diagnosis of Major Depressive Disorder
by Cyrus Su Hui Ho, Trevor Wei Kiat Tan, Howard Cai Hao Khoe, Yee Ling Chan, Gabrielle Wann Nii Tay and Tong Boon Tang
J. Clin. Med. 2024, 13(5), 1222; https://doi.org/10.3390/jcm13051222 - 21 Feb 2024
Cited by 4 | Viewed by 2046
Abstract
Background: Major depressive disorder (MDD) is a leading cause of disability worldwide. At present, however, there are no established biomarkers that have been validated for diagnosing and treating MDD. This study sought to assess the diagnostic and predictive potential of the differences in [...] Read more.
Background: Major depressive disorder (MDD) is a leading cause of disability worldwide. At present, however, there are no established biomarkers that have been validated for diagnosing and treating MDD. This study sought to assess the diagnostic and predictive potential of the differences in serum amino acid concentration levels between MDD patients and healthy controls (HCs), integrating them into interpretable machine learning models. Methods: In total, 70 MDD patients and 70 HCs matched in age, gender, and ethnicity were recruited for the study. Serum amino acid profiling was conducted by means of chromatography-mass spectrometry. A total of 21 metabolites were analysed, with 17 from a preset amino acid panel and the remaining 4 from a preset kynurenine panel. Logistic regression was applied to differentiate MDD patients from HCs. Results: The best-performing model utilised both feature selection and hyperparameter optimisation and yielded a moderate area under the receiver operating curve (AUC) classification value of 0.76 on the testing data. The top five metabolites identified as potential biomarkers for MDD were 3-hydroxy-kynurenine, valine, kynurenine, glutamic acid, and xanthurenic acid. Conclusions: Our study highlights the potential of using an interpretable machine learning analysis model based on amino acids to aid and increase the diagnostic accuracy of MDD in clinical practice. Full article
(This article belongs to the Section Mental Health)
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5 pages, 190 KiB  
Proceeding Paper
Discussion on Satisfaction and Loyalty of Women with Pelvic Treatment in Postpartum Period
by Wann-Jyi Horng and Ming-Chia Yeh
Eng. Proc. 2023, 55(1), 95; https://doi.org/10.3390/engproc2023055095 - 1 Feb 2024
Viewed by 580
Abstract
The satisfaction and loyalty of women in the postpartum period with their pelvic health and related treatment were investigated to provide a reference for the decision-making of operators. The study results showed that women’s age, education level, occupation, postpartum time, and mode of [...] Read more.
The satisfaction and loyalty of women in the postpartum period with their pelvic health and related treatment were investigated to provide a reference for the decision-making of operators. The study results showed that women’s age, education level, occupation, postpartum time, and mode of delivery influenced the cognition of and satisfaction with pelvic health recovery. The results also provided a reference for postpartum care centers or related practitioners to offer better choices in pelvic health care to secure the loyalty of women in the postpartum period. Based on these results, women in the postpartum period can improve their quality of life. Full article
33 pages, 11517 KiB  
Article
Novel Ocean Wave Height and Energy Spectrum Forecasting Approaches: An Application of Semi-Analytical and Machine Learning Models
by Ismail Elkhrachy, Ali Alhamami, Saleh H. Alyami and Aníbal Alviz-Meza
Water 2023, 15(18), 3254; https://doi.org/10.3390/w15183254 - 13 Sep 2023
Cited by 6 | Viewed by 3671
Abstract
Accurate and reliable wave forecasting is crucial for optimizing the performance of various marine operations, such as offshore energy production, shipping, and fishing. Meanwhile, predicting wave height and wave energy is crucial for achieving sustainability as a renewable energy source, as it enables [...] Read more.
Accurate and reliable wave forecasting is crucial for optimizing the performance of various marine operations, such as offshore energy production, shipping, and fishing. Meanwhile, predicting wave height and wave energy is crucial for achieving sustainability as a renewable energy source, as it enables the harnessing of the power of wave energy efficiently based on the water-energy nexus. Advanced wave forecasting models, such as machine learning models and the semi-analytical approach, have been developed to provide more accurate predictions of ocean waves. In this study, the Sverdrup Munk Bretschneider (SMB) semi-analytical approach, Emotional Artificial Neural Network (EANN) approach, and Wavelet Artificial Neural Network (WANN) approach will be used to estimate ocean wave parameters in the Gulf of Mexico and Aleutian Basin. The accuracy and reliability of these approaches will be evaluated, and the spatial and temporal variability of the wave field will be investigated. The available wave characteristics are used to generate hourly, 12-hourly, and daily datasets. The WANN and SMB model shows good performance in the daily prediction of the significant wave height in both case studies. In the SMB model, specifically on a daily time scale, the Nash–Sutcliffe Efficiency (NSE) and the peak deviation coefficient (DCpeak) were determined to be 0.62 and 0.54 for the Aleutian buoy and 0.64 and 0.55 for the Gulf of Mexico buoy, respectively, for significant wave height. In the context of the WANN model and in the testing phase at the daily time scale, the NSE and DCpeak indices exhibit values of 0.85 and 0.61 for the Aleutian buoy and 0.72 and 0.61 for the Gulf of Mexico buoy, respectively, while the EANN model is a strong tool in hourly wave height prediction (Aleutian buoy (NSEEANN = 0.60 and DCpeakEANN = 0.88), Gulf of Mexico buoy (NSEEANN = 0.80 and DCpeakEANN = 0.82)). In addition, the findings pertaining to the energy spectrum density demonstrate that the EANN model exhibits superior performance in comparison to the WANN and SMB models, particularly with regard to accurately estimating the peak of the spectrum (Aleutian buoy (DCpeakEANN= 0.41), Gulf of Mexico buoy (DCpeakEANN = 0.59)). Full article
(This article belongs to the Section Water Resources Management, Policy and Governance)
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21 pages, 1234 KiB  
Article
Forecasting and Inventory Planning: An Empirical Investigation of Classical and Machine Learning Approaches for Svanehøj’s Future Software Consolidation
by Hadid J. Wahedi, Mads Heltoft, Glenn J. Christophersen, Thomas Severinsen, Subrata Saha and Izabela Ewa Nielsen
Appl. Sci. 2023, 13(15), 8581; https://doi.org/10.3390/app13158581 - 25 Jul 2023
Cited by 6 | Viewed by 8311
Abstract
Challenges related to effective supply and demand planning and inventory management impose critical planning issues for many small and medium-sized enterprises (SMEs). In recent years, data-driven methods in machine learning (ML) algorithms have provided beneficial results for many large-scale enterprises (LSE). However, ML [...] Read more.
Challenges related to effective supply and demand planning and inventory management impose critical planning issues for many small and medium-sized enterprises (SMEs). In recent years, data-driven methods in machine learning (ML) algorithms have provided beneficial results for many large-scale enterprises (LSE). However, ML applications have not yet been tested in SMEs, leaving a technological gap. Limited recourse capabilities and financial constraints expose the risk of implementing an insufficient enterprise resource planning (ERP) setup, which amplifies the need for additional support systems for data-driven decision-making. We found the forecasts and determination of inventory management policies in SMEs are often based on subjective decisions, which might fail to capture the complexity of achieving performance goals. Our research aims to utilize the leverage of ML models for SMEs within demand and inventory management by considering various key performance indicators (KPI). The research is based on collaboration with a Danish SME that faced issues related to forecasting and inventory planning. We implemented the following ML models: Artificial Neural Network (ANN), Long Short-Term Memory (LSTM), Support Vector Regression (SVR), Random Forest (RF), Wavelet-ANN (W-ANN), and Wavelet-LSTM (W-LSTM) for forecasting purposes and reinforcement learning approaches, namely Q-learning and Deep Q Network (DQN) for inventory management. Results demonstrate that predictive ML models perform superior concerning the statistical forecasting approaches, but not always if we focus on industrial KPIs. However, when ML models are solely considered, the results indicate careful consideration must be regarded, given that model evaluation can be perceived from an academic and managerial perspective. Secondly, Q-learning is found to yield preferable economic results in terms of inventory planning. The proposed models can serve as an extension to modern ERP systems by offering a data-driven approach to demand and supply planning decision-making. Full article
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16 pages, 2435 KiB  
Article
The Utility of Amino Acid Metabolites in the Diagnosis of Major Depressive Disorder and Correlations with Depression Severity
by Cyrus Su Hui Ho, Gabrielle Wann Nii Tay, Hai Ning Wee and Jianhong Ching
Int. J. Mol. Sci. 2023, 24(3), 2231; https://doi.org/10.3390/ijms24032231 - 23 Jan 2023
Cited by 18 | Viewed by 3490
Abstract
Major depressive disorder (MDD) is a highly prevalent and disabling condition with a high disease burden. There are currently no validated biomarkers for the diagnosis and treatment of MDD. This study assessed serum amino acid metabolite changes between MDD patients and healthy controls [...] Read more.
Major depressive disorder (MDD) is a highly prevalent and disabling condition with a high disease burden. There are currently no validated biomarkers for the diagnosis and treatment of MDD. This study assessed serum amino acid metabolite changes between MDD patients and healthy controls (HCs) and their association with disease severity and diagnostic utility. In total, 70 MDD patients and 70 HCs matched in age, gender, and ethnicity were recruited for the study. For amino acid profiling, serum samples were analysed and quantified by liquid chromatography-mass spectrometry (LC-MS). Receiver-operating characteristic (ROC) curves were used to classify putative candidate biomarkers. MDD patients had significantly higher serum levels of glutamic acid, aspartic acid and glycine but lower levels of 3-Hydroxykynurenine; glutamic acid and phenylalanine levels also correlated with depression severity. Combining these four metabolites allowed for accurate discrimination of MDD patients and HCs, with 65.7% of depressed patients and 62.9% of HCs correctly classified. Glutamic acid, aspartic acid, glycine and 3-Hydroxykynurenine may serve as potential diagnostic biomarkers, whereas glutamic acid and phenylalanine may be markers for depression severity. To elucidate the association between these indicators and clinical features, it is necessary to conduct additional studies with larger sample sizes that involve a spectrum of depressive symptomatology. Full article
(This article belongs to the Section Molecular Neurobiology)
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14 pages, 1529 KiB  
Article
Comparison of Wavelet Artificial Neural Network, Wavelet Support Vector Machine, and Adaptive Neuro-Fuzzy Inference System Methods in Estimating Total Solar Radiation in Iraq
by Wongchai Anupong, Muhsin Jaber Jweeg, Sameer Alani, Ibrahim H. Al-Kharsan, Aníbal Alviz-Meza and Yulineth Cárdenas-Escrocia
Energies 2023, 16(2), 985; https://doi.org/10.3390/en16020985 - 16 Jan 2023
Cited by 15 | Viewed by 2723
Abstract
Estimating the amount of solar radiation is very important in evaluating the amount of energy that can be received from the sun for the construction of solar power plants. Using machine learning tools to estimate solar energy can be a helpful method. With [...] Read more.
Estimating the amount of solar radiation is very important in evaluating the amount of energy that can be received from the sun for the construction of solar power plants. Using machine learning tools to estimate solar energy can be a helpful method. With a high number of sunny days, Iraq has a high potential for using solar energy. This study used the Wavelet Artificial Neural Network (WANN), Wavelet Support Vector Machine (WSVM), and Adaptive Neuro-Fuzzy Inference System (ANFIS) techniques to estimate solar energy at Wasit and Dhi Qar stations in Iraq. RMSE, EMA, R2, and IA criteria were used to evaluate the performance of the techniques and compare the results with the actual measured value. The results showed that the WANN and WSVM methods had similar results in solar energy modeling. However, the results of the WANN technique were slightly better than the WSVM technique. In Wasit and Dhi Qar stations, the value of R2 for the WANN and WSVM methods was 0.89 and 0.86, respectively. The value of R2 in the WANN and WSVM methods in Wasit and Dhi Qar stations was 0.88 and 0.87, respectively. The ANFIS technique also obtained acceptable results. However, compared to the other two techniques, the ANFIS results were lower, and the R2 value was 0.84 and 0.83 in Wasit and Dhi Qar stations, respectively. Full article
(This article belongs to the Special Issue Performance Analysis of Novel Solar Energy Systems)
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16 pages, 2657 KiB  
Article
Multi-Sensor Respiratory–Swallow Telecare System for Safe Feeding in Different Trunk Inclinations: System Development and Clinical Application
by Wann-Yun Shieh, Chin-Man Wang, Yan-Ying Ju and Hsin-Yi Kathy Cheng
Sensors 2023, 23(2), 642; https://doi.org/10.3390/s23020642 - 6 Jan 2023
Viewed by 2166
Abstract
Proper positioning is especially important to ensure feeding and eating safely. With many nursing facilities restricting visitations and close contact during the coronavirus pandemic, there is an urgent need for remote respiratory–swallow monitoring. This study aimed to develop a semiautomatic feeding telecare system [...] Read more.
Proper positioning is especially important to ensure feeding and eating safely. With many nursing facilities restricting visitations and close contact during the coronavirus pandemic, there is an urgent need for remote respiratory–swallow monitoring. This study aimed to develop a semiautomatic feeding telecare system that provides instant feedback and warnings on-site and remotely. It also aimed to analyze the effects of trunk positions on respiratory–swallow coordination. A signal collector with multiple integrated sensors for real-time respiratory–swallow monitoring and warning was developed. A repeated measures design was implemented to evaluate the effects of trunk inclination angles on the swallow-related functions. Significant differences in inclination angles were discovered for swallowing apnea (p = 0.045) and total excursion time of thyroid cartilage (p = 0.037), and pairwise comparisons indicated that these differences were mostly present at 5° to 45°. Alerts were triggered successfully when undesired respiratory patterns or piecemeal occurred. The results indicated that a care recipient can swallow more easily when sitting upright (5°) than when leaning backward (45°). This telecare system provides on-site and remote respiratory–swallow monitoring and alerting for residents in care facilities and can serve as a pipeline for the early screening of swallowing dysfunction. Full article
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19 pages, 3234 KiB  
Article
Predicting of Daily PM2.5 Concentration Employing Wavelet Artificial Neural Networks Based on Meteorological Elements in Shanghai, China
by Qingchun Guo, Zhenfang He and Zhaosheng Wang
Toxics 2023, 11(1), 51; https://doi.org/10.3390/toxics11010051 - 3 Jan 2023
Cited by 84 | Viewed by 3663
Abstract
Anthropogenic sources of fine particulate matter (PM2.5) threaten ecosystem security, human health and sustainable development. The accuracy prediction of daily PM2.5 concentration can give important information for people to reduce their exposure. Artificial neural networks (ANNs) and wavelet-ANNs (WANNs) are [...] Read more.
Anthropogenic sources of fine particulate matter (PM2.5) threaten ecosystem security, human health and sustainable development. The accuracy prediction of daily PM2.5 concentration can give important information for people to reduce their exposure. Artificial neural networks (ANNs) and wavelet-ANNs (WANNs) are used to predict daily PM2.5 concentration in Shanghai. The PM2.5 concentration in Shanghai from 2014 to 2020 decreased by 39.3%. The serious COVID-19 epidemic had an unprecedented effect on PM2.5 concentration in Shanghai. The PM2.5 concentration during the lockdown in 2020 of Shanghai is significantly reduced compared to the period before the lockdown. First, the correlation analysis is utilized to identify the associations between PM2.5 and meteorological elements in Shanghai. Second, by estimating twelve training algorithms and twenty-one network structures for these models, the results show that the optimal input elements for daily PM2.5 concentration predicting models were the PM2.5 from the 3 previous days and fourteen meteorological elements. Finally, the activation function (tansig-purelin) for ANNs and WANNs in Shanghai is better than others in the training, validation and forecasting stages. Considering the correlation coefficients (R) between the PM2.5 in the next day and the input influence factors, the PM2.5 showed the closest relation with the PM2.5 1 day lag and closer relationships with minimum atmospheric temperature, maximum atmospheric pressure, maximum atmospheric temperature, and PM2.5 2 days lag. When Bayesian regularization (trainbr) was used to train, the ANN and WANN models precisely simulated the daily PM2.5 concentration in Shanghai during the training, calibration and predicting stages. It is emphasized that the WANN1 model obtained optimal predicting results in terms of R (0.9316). These results prove that WANNs are adept in daily PM2.5 concentration prediction because they can identify relationships between the input and output factors. Therefore, our research can offer a theoretical basis for air pollution control. Full article
(This article belongs to the Special Issue Air Pollution and COVID-19)
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15 pages, 2146 KiB  
Article
Video-Based Behaviorally Coded Movement Assessment for Adolescents with Intellectual Disabilities: Application in Leg Dribbling Performance
by Hsin-Yi Kathy Cheng, Wann-Yun Shieh, Yu-Chun Yu, Pao-Wen Li and Yan-Ying Ju
Sensors 2023, 23(1), 179; https://doi.org/10.3390/s23010179 - 24 Dec 2022
Viewed by 1935
Abstract
Measuring motor performance in individuals with intellectual disabilities (ID) is quite challenging. The objective of this study was to compare the motor performances of individuals with ID and those with typical development (TD) during soccer dribbling through video-based behavior-coded movement assessment along with [...] Read more.
Measuring motor performance in individuals with intellectual disabilities (ID) is quite challenging. The objective of this study was to compare the motor performances of individuals with ID and those with typical development (TD) during soccer dribbling through video-based behavior-coded movement assessment along with a wearable sensor. A cross-sectional research design was adopted. Adolescents with TD (N = 25) and ID (N = 29) participated in the straight-line and zigzag soccer dribbling tests. The dribbling performance was videotaped, and the footage was then analyzed with customized behavior-coding software. The coded parameters were the time for movement completion, the number of kicks, blocks, steps, the number of times the ball went out of bounds, the number of missed cones, and the trunk tilt angle. Participants with ID exhibited significantly poorer performance and demonstrated greater variances in many time and frequency domain parameters. It also revealed that participants with ID kicked with both feet while dribbling, whereas those with TD mainly used the dominant foot. The present findings demonstrated how the ID population differed from their peers in lower-extremity strategic control. The customized video-based behavior-coded approach provides an efficient and effective way to gather behavioral data and calculate performance parameter statistics in populations with intellectual disabilities. Full article
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18 pages, 6533 KiB  
Article
Compensation for Electrode Detachment in Electrical Impedance Tomography with Wearable Textile Electrodes
by Chang-Lin Hu, Zong-Yan Lin, Shu-Yun Hu, I-Cheng Cheng, Chih-Hsien Huang, Yu-Hao Li, Chien-Ju Li and Chii-Wann Lin
Sensors 2022, 22(24), 9575; https://doi.org/10.3390/s22249575 - 7 Dec 2022
Cited by 2 | Viewed by 2860
Abstract
Electrical impedance tomography (EIT) is a radiation-free and noninvasive medical image reconstruction technique in which a current is injected and the reflected voltage is received through electrodes. EIT electrodes require good connection with the skin for data acquisition and image reconstruction. However, detached [...] Read more.
Electrical impedance tomography (EIT) is a radiation-free and noninvasive medical image reconstruction technique in which a current is injected and the reflected voltage is received through electrodes. EIT electrodes require good connection with the skin for data acquisition and image reconstruction. However, detached electrodes are a common occurrence and cause measurement errors in EIT clinical applications. To address these issues, in this study, we proposed a method for detecting faulty electrodes using the differential voltage value of the detached electrode in an EIT system. Additionally, we proposed the voltage-replace and voltage-shift methods to compensate for invalid data from the faulty electrodes. In this study, we present the simulation, experimental, and in vivo chest results of our proposed methods to verify and evaluate the feasibility of this approach. Full article
(This article belongs to the Special Issue Intelligent Wearable Systems and Computational Techniques)
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12 pages, 2772 KiB  
Article
Dynamic Weight Agnostic Neural Networks and Medical Microwave Radiometry (MWR) for Breast Cancer Diagnostics
by Jolen Li, Christoforos Galazis, Larion Popov, Lev Ovchinnikov, Tatyana Kharybina, Sergey Vesnin, Alexander Losev and Igor Goryanin
Diagnostics 2022, 12(9), 2037; https://doi.org/10.3390/diagnostics12092037 - 23 Aug 2022
Cited by 13 | Viewed by 2420
Abstract
Background and Objective: Medical microwave radiometry (MWR) is used to capture the thermal properties of internal tissues and has usages in breast cancer detection. Our goal in this paper is to improve classification performance and investigate automated neural architecture search methods. Methods: We [...] Read more.
Background and Objective: Medical microwave radiometry (MWR) is used to capture the thermal properties of internal tissues and has usages in breast cancer detection. Our goal in this paper is to improve classification performance and investigate automated neural architecture search methods. Methods: We investigated extending the weight agnostic neural network by optimizing the weights using the bi-population covariance matrix adaptation evolution strategy (BIPOP-CMA-ES) once the topology was found. We evaluated and compared the model based on the F1 score, accuracy, precision, recall, and the number of connections. Results: The experiments were conducted on a dataset of 4912 patients, classified as low or high risk for breast cancer. The weight agnostic BIPOP-CMA-ES model achieved the best average performance. It obtained an F1-score of 0.933, accuracy of 0.932, precision of 0.929, recall of 0.942, and 163 connections. Conclusions: The results of the model are an indication of the promising potential of MWR utilizing a neural network-based diagnostic tool for cancer detection. By separating the tasks of topology search and weight training, we can improve the overall performance. Full article
(This article belongs to the Section Point-of-Care Diagnostics and Devices)
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19 pages, 4626 KiB  
Article
Sequence Similarity Network Analysis Provides Insight into the Temporal and Geographical Distribution of Mutations in SARS-CoV-2 Spike Protein
by Shruti S. Patil, Helen N. Catanese, Kelly A. Brayton, Eric T. Lofgren and Assefaw H. Gebremedhin
Viruses 2022, 14(8), 1672; https://doi.org/10.3390/v14081672 - 29 Jul 2022
Cited by 1 | Viewed by 2612
Abstract
Severe acute respiratory syndrome-related coronavirus (SARS-CoV-2), which still infects hundreds of thousands of people globally each day despite various countermeasures, has been mutating rapidly. Mutations in the spike (S) protein seem to play a vital role in viral stability, transmission, and adaptability. Therefore, [...] Read more.
Severe acute respiratory syndrome-related coronavirus (SARS-CoV-2), which still infects hundreds of thousands of people globally each day despite various countermeasures, has been mutating rapidly. Mutations in the spike (S) protein seem to play a vital role in viral stability, transmission, and adaptability. Therefore, to control the spread of the virus, it is important to gain insight into the evolution and transmission of the S protein. This study deals with the temporal and geographical distribution of mutant S proteins from sequences gathered across the US over a period of 19 months in 2020 and 2021. The S protein sequences are studied using two approaches: (i) multiple sequence alignment is used to identify prominent mutations and highly mutable regions and (ii) sequence similarity networks are subsequently employed to gain further insight and study mutation profiles of concerning variants across the defined time periods and states. Additionally, we tracked the variants using visualizations on geographical maps. The visualizations produced using the Directed Weighted All Nearest Neighbors (DiWANN) networks and maps provided insights into the transmission of the virus that reflect well the statistics reported for the time periods studied. We found that the networks created using DiWANN are superior to commonly used approximate distance networks created using BLAST bitscores. The study offers a richer computational approach to analyze the transmission profile of the prominent S protein mutations in SARS-CoV-2 and can be extended to other proteins and viruses. Full article
(This article belongs to the Special Issue Bioinformatics Research on SARS-CoV-2)
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