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7 Results Found

  • Article
  • Open Access
8 Citations
6,327 Views
13 Pages
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Profiling and Preparation of Metabolites from Pyragrel in Human Urine by Online Solid-Phase Extraction Coupled with High Performance Liquid Chromatography Tandem Mass Spectrometry Followed by a Macroporous Resin-Based Purification Approach

  • Xin Zhao,
  • Jingjing Jiang,
  • Guang Yang,
  • Jie Huang,
  • Guoping Yang,
  • Guangwei He,
  • Zhaoxing Chu,
  • Taijun Hang and
  • Guorong Fan
Molecules2017, 22(3), 494;https://doi.org/10.3390/molecules22030494

21 March 2017

Pyragrel, a new anticoagulant drug, is derived from the molecular combination of ligustrazine and ferulic acid. Pyragrel showed significant inhibitory activity against platelet aggregation induced by adenosine diphosphate (ADP), and had been approved...

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  • Article
  • Open Access
29 Citations
7,720 Views
13 Pages
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Isolation, Characterization and Structural Elucidation of Polybutylene Terephthalate Cyclic Oligomers and Purity Assessment Using a 1H qNMR Method

  • Emmanouil D. Tsochatzis,
  • Joao Alberto Lopes,
  • Margaret V. Holland,
  • Fabiano Reniero,
  • Hendrik Emons and
  • Claude Guillou
Polymers2019, 11(3), 464;https://doi.org/10.3390/polym11030464

11 March 2019

The use of polybutylene terephthalate (PBT) as a food contact material is increasing over the last years. Typical contaminations in the final PBT product include its cyclic oligomers, which are allowed as additives in food contact plastics according...

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  • Article
  • Open Access
26 Citations
5,103 Views
15 Pages
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Separation and Enrichment of Three Coumarins from Angelicae Pubescentis Radix by Macroporous Resin with Preparative HPLC and Evaluation of Their Anti-Inflammatory Activity

  • Yuqiao Yang,
  • Ruichao Zhu,
  • Jin Li,
  • Xuejing Yang,
  • Jun He,
  • Hui Wang and
  • Yanxu Chang
Molecules2019, 24(14), 2664;https://doi.org/10.3390/molecules24142664

23 July 2019

In order to enrich and separate three coumarins (columbianetin acetate, osthole and columbianadin) from Angelicae Pubescentis Radix (APR), an efficient method was established by combining macroporous resins (MARs) with preparative high-performance li...

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  • Article
  • Open Access
24 Citations
8,588 Views
20 Pages
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Analysis of the Constituents in “Zhu She Yong Xue Shuan Tong” by Ultra High Performance Liquid Chromatography with Quadrupole Time-of-Flight Mass Spectrometry Combined with Preparative High Performance Liquid Chromatography

  • Lin-Lin Wang,
  • Li-Feng Han,
  • He-Shui Yu,
  • Mang-Mang Sang,
  • Er-Wei Liu,
  • Yi Zhang,
  • Shi-Ming Fang,
  • Tao Wang and
  • Xiu-Mei Gao
Molecules2015, 20(11), 20518-20537;https://doi.org/10.3390/molecules201119712

18 November 2015

“Zhu She Yong Xue Shuan Tong” lyophilized powder (ZSYXST), consists of a series of saponins extracted from Panax notoginseng, which has been widely used in China for the treatment of strokes. In this study, an ultra-high performance liquid chromatogr...

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  • Article
  • Open Access
10 Citations
4,309 Views
12 Pages
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Lipophilicity Studies on Thiosemicarbazide Derivatives

  • Agata Paneth,
  • Anna Hawrył,
  • Tomasz Plech,
  • Mirosław Hawrył,
  • Ryszard Świeboda,
  • Dominika Janowska,
  • Monika Wujec and
  • Piotr Paneth
Molecules2017, 22(6), 952;https://doi.org/10.3390/molecules22060952

8 June 2017

The lipophilicity of two series of thiosemicarbazide derivatives was assessed by the RP-HPLC method with the RP-18 chromatographic column and the methanol–water mixture as the mobile phase. Distribution coefficients logPHPLC were compared to calculat...

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  • Article
  • Open Access
25 Citations
5,975 Views
14 Pages
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Rapid Determination of Major Compounds in the Ethanol Extract of Geopropolis from Malaysian Stingless Bees, Heterotrigona itama, by UHPLC-Q-TOF/MS and NMR

  • Lingling Zhao,
  • Mengjiao Yu,
  • Minghui Sun,
  • Xiaofeng Xue,
  • Tongtong Wang,
  • Wei Cao and
  • Liping Sun
Molecules2017, 22(11), 1935;https://doi.org/10.3390/molecules22111935

10 November 2017

A reliable, rapid analytical method was established for the characterization of constituents of the ethanol extract of geopropolis (EEGP) produced by Malaysian stingless bees—Heterotrigona itama—by combining ultra-high-performance liquid chromatograp...

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  • Article
  • Open Access
51 Citations
6,766 Views
13 Pages
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Optimum Production Conditions, Purification, Identification, and Antioxidant Activity of Violaxanthin from Microalga Eustigmatos cf. polyphem (Eustigmatophyceae)

  • Feifei Wang,
  • Luodong Huang,
  • Baoyan Gao and
  • Chengwu Zhang
Mar. Drugs2018, 16(6), 190;https://doi.org/10.3390/md16060190

1 June 2018

Violaxanthin is a major xanthophyll pigment in the microalga Eustigmatos cf. polyphem, but the amount produced after propagation can vary depending upon culture conditions. In this study, the effects of cultivation time, nitrogen concentration, light...

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