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Article

733 Views

19 Pages

Granulosa Cell-Secreted KITL Is Involved in Maintaining Zinc Homeostasis in the Oocytes of Neonatal Mouse Ovaries

Yan Du,
Lincheng Han,
Hongwei Wei,
Xiaodan Zhang,
Wenbo Zhang,
Yashuang Weng,
Weiyong Wang,
Luchun Zhang,
Sihui He and
Jingjie Li

Antioxidants2025, 14(11), 1345;https://doi.org/10.3390/antiox14111345

10 November 2025

Proto-oncogenic receptor tyrosine kinase (KIT) ligand (KITL) secreted by granulosa cells and its receptor KIT on oocytes are crucial for primordial follicle formation and activation, and follicular development. In the present study, ZnSO4 decreased t...

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Article

12 Pages

Gene Expression Profiles of Melanocytes Over-Expressing miR-5110 in Alpaca

Shanshan Yang,
Dingxing Jiao,
Fengsai Li,
Xuqi Wang,
Tao Song,
Lili Wang,
Ping Rui and
Zengjun Ma

Curr. Issues Mol. Biol.2026, 48(1), 93;https://doi.org/10.3390/cimb48010093
(registering DOI)

16 January 2026

Previous studies have shown that miR-5110 regulates pigmentation by cotargeting melanophilin (MLPH) and WNT family member 1 (WNT1). In order to find the possible molecular mechanism for pigmentation, we examined the mRNA expression profiles in melano...

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Article

21 Citations

3,949 Views

13 Pages

ACE Inhibition Modulates Myeloid Hematopoiesis after Acute Myocardial Infarction and Reduces Cardiac and Vascular Inflammation in Ischemic Heart Failure

Wolf-Stephan Rudi,
Michael Molitor,
Venkata Garlapati,
Stefanie Finger,
Johannes Wild,
Thomas Münzel,
Susanne H. Karbach and
Philip Wenzel

Antioxidants2021, 10(3), 396;https://doi.org/10.3390/antiox10030396

5 March 2021

Aims: Angiotensin-converting-enzyme inhibitors (ACE inhibitors) are a cornerstone of drug therapy after myocardial infarction (MI) and improve left ventricular function and survival. We aimed to elucidate the impact of early treatment with the ACE in...

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Article

4 Citations

2,603 Views

22 Pages

Comparative Study of Metastasis Suppression Effects of Extracellular Vesicles Derived from Anaplastic Cell Lines, Nanog-Overexpressing Melanoma, and Induced Pluripotent Stem Cells

Celine Swee May Khoo,
Takuya Henmi and
Mikako Saito

Int. J. Mol. Sci.2023, 24(24), 17206;https://doi.org/10.3390/ijms242417206

6 December 2023

Previous studies have demonstrated that extracellular vesicles (EVs) derived from an anaplastic mouse melanoma cell line made using Nanog overexpression of F10 (Nanog+F10) suppressed the metastasis of Nanog+F10. Here, an induced pluripotent stem (iPS...

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Article

31 Citations

8,682 Views

13 Pages

Parabens Accelerate Ovarian Dysfunction in a 4-Vinylcyclohexene Diepoxide-Induced Ovarian Failure Model

Jae-Hwan Lee,
Myeongho Lee,
Changhwan Ahn,
Hee Young Kang,
Dinh Nam Tran and
Eui-Bae Jeung

Int. J. Environ. Res. Public Health2017, 14(2), 161;https://doi.org/10.3390/ijerph14020161

8 February 2017

Parabens are widely used preservatives in basic necessities such as cosmetic and pharmaceutical products. In previous studies, xenoestrogenic actions of parabens were reported in an immature rat model and a rat pituitary cell line (GH3 cells). The re...

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