1,403 Results Found

Both non-immune “natural” and antigen-induced “immune” IgM are important for protection against pathogens and for regulation of immune responses to self-antigens. Since the bona fide IgM Fc receptor (FcµR) was identified in humans by a functional clo...

Tumor-targeting monoclonal antibodies (mAbs) are the most widely used and characterized immunotherapy for hematologic and solid tumors. The significance of this therapy is their direct and indirect effects on tumor cells, facilitated by the antibody&...

Currently, the transmission system operators (TSOs) from Portugal and Spain do not procure a frequency containment reserve (FCR) through market mechanisms. In this context, a virtual power plant (VPP) that aggregates sources, such as wind and solar p...

Feed conversion ratio (FCR) is a critical indicator of production efficiency in livestock husbandry. Improving FCR is essential for optimizing resource utilization and enhancing productivity. Traditional methods for FCR optimization rely on experienc...

This paper presents the case study of provisions of frequency containment reserve (FCR) with a battery electric storage system (BESS). The aim of the case study is the evaluation of the technical possibility to provide FCR in Latvian power systems af...

The re-emergence of the mpox pandemic poses considerable challenges to human health and societal development. There is an urgent need for effective prevention and treatment strategies against the mpox virus (MPXV). In this study, we focused on the A3...

Novel therapeutic approaches are much needed for the treatment of osteosarcoma. Targeted radionuclide therapy (TRT) and radioimmunotherapy (RIT) are promising approaches that deliver therapeutic radiation precisely to the tumor site. We have previous...

The study of the forest coverage rate (FCR) is related to the ecological environment and sustainable development goals (SDGs) of a region. In light of the lack of an organic integration method of “spatiotemporal evolution, correlation analysis,...

Endotoxin (lipopolysaccharide) testing of drugs is routinely required in pharmaceutical industries. Suitable compendial assays are defined by national pharmacopoeias. At this time, Limulus Amoebocyte Lysate (LAL) assays are the gold standard. LAL is...

The half life of recombinant factor VIII-Fc (rFVIII-Fc) for people with hemophilia A (PwHA) varies greatly. Understanding the factors influencing the variation and assessment of rFVIII-Fc half life is important for personalized treatment. Eighty-five...

Introduction: Chronic lymphocytic leukemia (CLL) is a common adult leukemia often treated with fludarabine, cyclophosphamide, and rituximab (FCR). While effective, FCR can lead to therapy-related myeloid neoplasms (t-MN), including aggressive therapy...

To assess the impact of first-line treatment with targeted agents (TAs) or fludarabine, cyclophosphamide, and rituximab (FCR)-based chemo-immunotherapy (CIT) on overall survival (OS) compared to age- and sex-matched individuals in the general populat...

As part of the non-clinical safety package characterizing bamlanivimab (SARS-CoV-2 neutralizing monoclonal antibody), the risk profile for antibody-dependent enhancement of infection (ADE) was evaluated in vitro and in an African green monkey (AGM) m...

Establishing an immune balance between the mother and fetus during gestation is crucial, with the placenta acting as the epicenter of immune tolerance. The placental transfer of antibodies, mainly immunoglobulin G (IgG), is critical in protecting the...

IgM is the first antibody to emerge during phylogeny, ontogeny, and immune responses and serves as a first line of defense. Effector proteins interacting with the Fc portion of IgM, such as complement and its receptors, have been extensively studied...

Background/Objectives: Recombinant Fc proteins have been produced that have a protective effect in mouse models of arthritis, such as the K/BxN rheumatoid arthritis model. We have previously shown that a recombinant human IgG1 Fc with a point mutatio...

The strawberry is a low-growing, herbaceous perennial plant, sensitive to iron deficiency. The iron deficiency represents a nutritional disorder, leading to a decreased content of photosynthetic pigments, which determines the yellow color characteris...

Background and Objectives: Fears of cancer recurrence (FCR) represents one of the most common psychological problems in cancer patients. Therefore, valid and reliable measurement tools are needed to assess FCR in this population. The purpose of this...

Background: Thyroid eye disease (TED) is a rare autoimmune orbital disorder predominantly associated with Graves’ disease. It is characterized by orbital inflammation, tissue remodeling, and potential visual morbidity. Conventional therapies, p...

This paper reports on the use of estimates of individual animal feed intake (made using time spent feeding measurements) to predict the Feed Conversion Ratio (FCR), a measure of the amount of feed consumed to produce 1 kg of body mass, for an individ...

The increased penetration of renewable energy sources in the electrical grid raises the need for more power system flexibility. One of the high potential groups to provide such flexibility is the industry. Incentives to do so are provided by variable...

Receptors for the immunoglobulin G constant fraction (FcγRs) are widely expressed in cells of the immune system. Complement-independent phagocytosis prompted FcγR research to show that the engagement of IgG immune complexes with Fcγ...

Improving irrigation performance is crucial for increased agricultural productivity. As an indicator of performance, among other factors, improving the water Fees Collection Rate (FCR) is required, but FCR has remained low in most African and Asian c...

Fear of cancer recurrence (FCR) affects approximately 50% of family caregivers. While FCR in cancer patients has been well-documented, less is known about the experience of FCR in family caregivers. This study aimed to qualitatively explore the disti...

Gram-negative bacterial endotoxins can cause pathophysiological effects such as high fever when introduced into the bloodstream. Therefore, endotoxin testing is necessary when producing injectable pharmaceuticals. The pharmaceutical industry has wide...

The fragment crystallizable (Fc) domain of antibodies is responsible for their protective function and long-lasting serum half-life via Fc-mediated effector function, transcytosis, and recycling through its interaction with Fc receptors (FcRs) expres...

This study investigates the technical and financial potential of an aggregation of residential heat pumps to deliver demand response (DR) services to the Dutch Frequency Containment Reserve (FCR) market. To determine this potential, a quantitative mo...

Multiple species of Fusarium can infect wheat and barley plants at various stages of development. Fusarium head blight (FHB) refers to the infection of spikes and developing kernels by these pathogens, and crown rot (FCR) infers to infection of the r...

Fusarium head blight (FHB) and Fusarium crown rot (FCR) are managed by the application of imidazole fungicides, which will be strictly limited by 2030, as stated by the European Green Deal. Here, a novel and eco-sustainable nanostructured particle fo...

The effect of combining filler (carbon black) and fibrous materials (steel fiber and polypropylene fiber) with various sizes of coarse particles on the post-cracking behavior of conductive concrete was investigated in this study. Steel fibers (SF) an...

Structural health monitoring of concrete infrastructure is a critical concern for timely repair and maintenance. This study provides an innovative approach utilizing smart concrete integrated with multi-walled carbon nanotubes (MWCNTs) to enhance ele...

Background/Objectives: Fear of recurrence is one of the main issues affecting cancer patients after the completion of treatment. Despite the development of various assessment tools at the international level, there is a lack of validated questionnair...

Infection of liver flukes (Opisthorchis viverrini) is partly due to their suitability for habitats in sub-basin areas, which causes the intermediate host to remain in the watershed system in all seasons. The spatial monitoring of fluke at the small b...

Animal temperament evaluation can be included in the cattle selection program also because of an existing correlation with performance. However, there are different assessment methods such as flight speed (time and speed that an animal takes to leave...

Changes in root organization and colonization could be relevant for wheat’s (Triticum durum Desf.) response to F. culmorum-induced crown rot disease (FCR). We investigated the biocontrol and biostimulant efficiency of seeds coated with T. harzi...

As the number of available renewable energy sources has increased annually, there has been a corresponding rise in the levels of pollution created by traditional electricity generation, ultimately contributing to breaking down the stability of the el...

Background: EphrinA1-Fc abolishes acute I/R injury and attenuates nonreperfused cardiac injury 4 days after permanent occlusion in mice. The goal of this study was to assess the capacity of a single intramyocardial administration of ephrinA1-Fc at th...

The broiler industry is the most developed livestock sector in Cameroon. This study aimed to evaluate the relationship between biosecurity implementation with production performance and antibiotic usage in broiler farms in Cameroon. Data concerning b...

Accurate detection of microbial contamination is essential in the assessment of toxicological and immunological responses to various materials, as low-level contaminants can lead to confounding results. Traditional endotoxin testing relies on the Lim...

Recently, ecological and economic issues have affected fish meal (FM) supply, the main source of protein for shrimp. This triggered a search for alternative dietary protein sources for shrimp production. We studied the consequences of replacing FM wi...

The high cost of commercial feed presents a major barrier to scaling environmentally responsible cricket (Acheta domesticus) farming, particularly in low-resource settings. We investigated the use of Hermetia illucens (Black Soldier Fly Larvae, BSFL)...

Pig manure (PM) is often highly enriched in heavy metals, such as Cu and Zn, due to the wide use of feed additives. To study the potential risks of heavy metal accumulation in the soil and rice grains by the application of PM and other organic manure...

Antibody Dependent Enhancement (ADE) of an infection has been of interest in the investigation of many viruses. It is associated with the severity of the infection. ADE is mediated by non-neutralizing antibodies, antibodies at sub-neutralizing concen...

The present study set out to determine the effects of incorporating cDDGS into starter, grower, and finisher diets (containing 5%, 10%, and 15% of cDDGS, respectively) on growth performance, carcass and meat quality, and cost effectiveness of pig fat...

Interleukin (IL)-23 is considered an effective therapeutic target for the treatment of psoriasis because of the crucial role of the IL-23/IL-17 axis in the pathogenesis of psoriasis, and it has recently been reported to be involved in ILC3 cell diffe...

Aquaponics is a sustainable method of food production, whereby aquaculture and hydroponics are combined in one circular system. A few aquaponics startup companies are emerging in Europe with a limited production area of a few hundred or a few thousan...

Infection with liver flukes (Opisthorchis viverrini) is partly due to their ability to thrive in habitats in sub-basin areas, causing the intermediate host to remain in the watershed system throughout the year. Spatial modeling is used to predict wat...

The present study evaluated water quality, immune responses, nutritional condition, and production of Ompok pabda fry (0.29–0.31 g) reared in a Biofloc technology (BFT) system (C:N = 20:1; molasses as organic carbon source), compared to the tra...

The accurate extraction of agricultural parcels from remote sensing images is crucial for advanced agricultural management and monitoring systems. Existing methods primarily emphasize regional accuracy over boundary quality, often resulting in fragme...

F. communis and D. viscosa are perennial Mediterranean weeds that have been used for different therapeutic purposes in traditional pharmacopeia. Plant extracts were obtained from air dried D. viscosa young shoots (DvA) and F. communis aerial part (Fc...