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  • Article
  • Open Access
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19 Pages

Optimization of Subcritical Water Extraction Process for Polyphenols from Cinchona calisaya and Their Activity Analysis

  • Guangxin Li,
  • Yujie Zhou,
  • Dong Xie,
  • Jingwen Zhang,
  • Zhengshan Hu,
  • Yuanping He,
  • Lihua Zou,
  • Ping Zhao,
  • Yingjun Zhang and
  • Sengkew Wee
  • + 1 author

12 February 2026

This study expands research on Cinchona calisaya, which has traditionally focused on alkaloids, to address the insufficient comprehensive utilization of its resources. It is the first to explore the feasibility of extracting phenolic compounds from C...