Sign in to use this feature.

Years

Between: -

Subjects

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Journals

Article Types

Countries / Regions

remove_circle_outline
remove_circle_outline
remove_circle_outline

Search Results (270)

Search Parameters:
Keywords = CNTs-based sensor

Order results
Result details
Results per page
Select all
Export citation of selected articles as:
25 pages, 1040 KB  
Review
Innovative Nanowire Structures for Sensors: Advanced Synthetic Nanowire Strategies
by Cheng Pu, Yao Zhou, Jianxing Zhao, Ao Wang, Jianhong Zhou and Chonge Wang
Crystals 2026, 16(3), 173; https://doi.org/10.3390/cryst16030173 - 3 Mar 2026
Abstract
This systematic review presents a critical analysis of multifunctional nanowire sensors, with explicit selection criteria for included studies: we focus on peer-reviewed research, prioritizing studies on semiconductor (ZnO, TiO2, Si), metal (Ag, Au), and carbon-based (CNT) nanowires that report structural innovations, [...] Read more.
This systematic review presents a critical analysis of multifunctional nanowire sensors, with explicit selection criteria for included studies: we focus on peer-reviewed research, prioritizing studies on semiconductor (ZnO, TiO2, Si), metal (Ag, Au), and carbon-based (CNT) nanowires that report structural innovations, performance breakthroughs, or industrial scalability. We systematically analyze their structural characteristics, advanced fabrication techniques (hydrothermal synthesis, magnetron sputtering, PECVD), and application performance across biosensing, pressure sensing, and gas monitoring. Unlike existing reviews limited to single material classes or application scenarios, this work advances the field by integrating three novel perspectives: it delivers a cross-material comparison of nanowire structure–performance relationships, incorporates an analysis of fabrication strategy scalability for industrial translation, and synthesizes unresolved challenges and future directions. Nanowire sensors exhibit superior sensitivity, rapid response, and broad detection ranges compared to conventional sensors, with significant potential to advance healthcare, environmental monitoring, and flexible electronics. Full article
(This article belongs to the Special Issue Thin Film Materials for Sensors)
Show Figures

Figure 1

14 pages, 3436 KB  
Article
A Battery-Free, Data-Informed UV Dose Sensor Made of Laser-Induced Graphene and Bio-Derived Electrolytes
by Mohammadreza Chimerad, Pouya Borjian, Faisal Bin Kashem, Swaminathan Rajaraman and Hyoung J. Cho
Micromachines 2026, 17(3), 302; https://doi.org/10.3390/mi17030302 - 28 Feb 2026
Viewed by 118
Abstract
This study presents a sustainable, battery-free UV (ultraviolet) dose sensor designed for intelligent food packaging applications. The device integrates laser-induced graphene (LIG) electrodes, a ZnO-CNT (carbon nanotube) UV-active composite, and a bio-derived ionochromic cell composed of blueberry anthocyanins and a NaCl electrolyte. This [...] Read more.
This study presents a sustainable, battery-free UV (ultraviolet) dose sensor designed for intelligent food packaging applications. The device integrates laser-induced graphene (LIG) electrodes, a ZnO-CNT (carbon nanotube) UV-active composite, and a bio-derived ionochromic cell composed of blueberry anthocyanins and a NaCl electrolyte. This work advances the platform by introducing a quantitative and predictive dose–color mapping framework for cumulative UV detection under zero-bias operation. A controlled charge-injection protocol was employed to emulate UV-generated photocurrent, enabling systematic investigation of charge-transfer-driven ionochromic kinetics across five current levels (0.2–3 mA). HSB (hue–saturation–brightness)-based colorimetric analysis was performed to quantify the time-dependent chromatic evolution, and a numerical fitting model was developed to map charge accumulation to color shifts. Using this calibration, the color response at microampere-level photocurrents—corresponding to real zero-bias UV operation—can be predicted. The resulting model enables estimation of the cumulative time required for the ionochromic cell to transition from red to purple under realistic UV intensities. By combining self-powered sensing with predictive colorimetric modeling, this work significantly enhances the functionality of battery-free UV indicators, enabling quantitative dose measurement without external electronics for safer food-supply-chain monitoring. Full article
(This article belongs to the Special Issue Solid-State Sensors, Actuators and Microsystems—Transducers 2025)
Show Figures

Figure 1

12 pages, 8765 KB  
Article
Aptamer-Based Dual-Cascade Signal Amplification System Lights up G-Quadruplex Dimers for Ultrasensitive Detection of Domoic Acid
by Jiansen Li, Zhenfei Xu, Zexuan Zhang, Rui Liu, Yuping Zhu, Xiaoling Lu, Huiying Xu, Xiaoyu Liu, Zhe Ning, Xinyuan Wang, Haobing Yu and Bo Hu
Mar. Drugs 2026, 24(1), 50; https://doi.org/10.3390/md24010050 - 21 Jan 2026
Viewed by 454
Abstract
In recent years, harmful algal blooms have led to frequent occurrences of shellfish toxin contamination, posing a significant threat to the safety of aquatic products and public health. As a potent neurotoxin, domoic acid (DA) can accumulate in shellfish, highlighting the urgent need [...] Read more.
In recent years, harmful algal blooms have led to frequent occurrences of shellfish toxin contamination, posing a significant threat to the safety of aquatic products and public health. As a potent neurotoxin, domoic acid (DA) can accumulate in shellfish, highlighting the urgent need for rapid and highly sensitive detection methods. In this study, we developed a fluorescent aptasensor based on a dual-signal amplification system by combining G-quadruplex (G4) dimers with multi-walled carbon nanotubes (CNTs). The sensor is designed with a hairpin-structured aptamer as the recognition probe, where short multi-walled CNTs serve as both a fluorescence quencher and platform, and G4 dimers are incorporated into the sensing interface to enhance signal output. In the absence of the target, the hairpin-structured aptamer remains closed, keeping the fluorescence signal “off”. Upon binding to DA, the aptamer undergoes a specific conformational change that exposes the G4-dimer sequence. The exposed sequence then binds to thioflavin T (ThT), which in turn generates a greatly enhanced fluorescence signal, leading to a substantial fluorescence enhancement and completing the second stage of the cascade amplification. Under optimal conditions, the constructed sensor achieves rapid detection of DA within 5 min, with a low detection limit of 1.1 ng/mL. This work presents a valuable tool for the rapid and sensitive detection of DA in shellfish, with promising applications in marine environmental monitoring and food safety regulation. Full article
(This article belongs to the Special Issue Marine Biotoxins, 4th Edition)
Show Figures

Figure 1

22 pages, 16177 KB  
Article
Enhanced Performance of an Electrochemical Sensor Using CNT Membrane for Accumulation-Based Detection of Nanoparticles
by Azam Usefian Babukani, Maziar Jafari, Paul-Vahe Cicek and Ricardo Izquierdo
Chemosensors 2026, 14(1), 12; https://doi.org/10.3390/chemosensors14010012 - 2 Jan 2026
Viewed by 510
Abstract
A carbon nanotube (CNT)-integrated microfluidic electrochemical sensor was developed for sensitive nanoparticle detection using gold nanoparticles (AuNPs) as the model analyte. The device incorporated screen-printed polyethylene terephthalate (PET) electrodes, a polydimethylsiloxane (PDMS) microchannel, and a CNT membrane that simultaneously served as a filtration [...] Read more.
A carbon nanotube (CNT)-integrated microfluidic electrochemical sensor was developed for sensitive nanoparticle detection using gold nanoparticles (AuNPs) as the model analyte. The device incorporated screen-printed polyethylene terephthalate (PET) electrodes, a polydimethylsiloxane (PDMS) microchannel, and a CNT membrane that simultaneously served as a filtration layer and working electrode. This configuration enhanced analyte trapping, increased the electroactive surface area, and accelerated electron transfer under convective flow. The CNT membrane was fabricated by vacuum filtration and torch-assisted bonding, ensuring strong adhesion without adhesives or plasma treatment. Electrochemical analysis showed that the filter-integrated CNT sensor exhibited an oxidation current of 63 µA compared to 11 µA for the non-filter sensor, representing a fifteen-fold sensitivity enhancement. The detection limit improved from 1.0 × 10−3 to 7.5 × 10−4 mol·L−1 with excellent reproducibility (RSD < 5%) and ∼90% accuracy. These findings validated the filtration-assisted accumulation mechanism and demonstrated the effectiveness of CNT-integrated microfluidic sensors for enhanced nanoparticle detection, while highlighting their potential for future adaptation to biosensing applications. Full article
(This article belongs to the Special Issue Emerging 2D Materials for Sensing Applications)
Show Figures

Figure 1

21 pages, 5066 KB  
Article
Design and Performance Analysis of a Hybrid Flexible Pressure Sensor with Wide Linearity and High Sensitivity
by Qinghua Zhang, Zhenxing Liu, Jianbo Wu, Ping Sun and Hanwen Zhang
Sensors 2026, 26(1), 238; https://doi.org/10.3390/s26010238 - 30 Dec 2025
Cited by 1 | Viewed by 431
Abstract
This study presents a wide-linear-range flexible pressure sensor based on a gradient non-uniform porous structure. Through co-optimization of material composition and structural parameters, the sensor integrates high sensitivity, a broad linear response range, and excellent stability. The sensing layer is fabricated using a [...] Read more.
This study presents a wide-linear-range flexible pressure sensor based on a gradient non-uniform porous structure. Through co-optimization of material composition and structural parameters, the sensor integrates high sensitivity, a broad linear response range, and excellent stability. The sensing layer is fabricated using a PVC/CNT composite slurry, with interdigital silver electrodes screen-printed on a PET substrate. A porous architecture is constructed via solution blending and a template method. Innovatively, orthogonal experiments were employed to optimize the conductive filler concentration and porosity. A mixed sugar template comprising particles of 50–75 μm and 125–150 μm was introduced to form a gradient non-uniform porous structure, effectively expanding the linear response range. Experimental results demonstrate that the sensor exhibits outstanding linearity (R2 > 0.99) and high sensitivity (5.57 kPa−1) over a broad pressure range of 0–120 kPa. It also shows a dynamic response speed of 50 ms, cyclic stability exceeding 500 cycles, and signal fluctuation of less than 5%. Scanning electron microscopy (SEM) analysis reveals the synergistic mechanism of the non-uniform pores, confirming the effectiveness of this design in reconciling the trade-off between sensitivity and linear range. This study offers new insights into the performance optimization of flexible pressure sensors and demonstrates significant potential for applications in health monitoring and electronic skin (E-skin). Full article
(This article belongs to the Section Sensor Materials)
Show Figures

Figure 1

13 pages, 2669 KB  
Article
Highly Dispersible and Stable Carbon Nanotube Ink with Silicone Elastomer for Piezoresistive Sensing
by Hyun Jae Lee, Justin Rejimone, Simon S. Park and Keekyoung Kim
Micromachines 2026, 17(1), 14; https://doi.org/10.3390/mi17010014 - 24 Dec 2025
Viewed by 421
Abstract
An alternative conductive ink based on carbon nanotubes (CNTs) was developed using a platinum-catalyzed silicone elastomer and isopropyl alcohol (IPA). The inclusion of IPA in the conductive CNT ink facilitated the optimization of its mechanical strength, electrical conductivity, and viscosity. Compared to conventional [...] Read more.
An alternative conductive ink based on carbon nanotubes (CNTs) was developed using a platinum-catalyzed silicone elastomer and isopropyl alcohol (IPA). The inclusion of IPA in the conductive CNT ink facilitated the optimization of its mechanical strength, electrical conductivity, and viscosity. Compared to conventional silicone rubber-based conductive polymers that often solidify in a few hours at room temperature or with heating, this liquid composite of CNT particles and IPA exhibited a prolonged duration of up to several months in a hermetic environment, maintaining chemical stability even with the elastomer and its curing agent. The gradual evaporation of IPA initiates a well-known cross-linking process, leading to stretchability and electrical conductivity derived from the silicone elastomer and CNT particles, respectively. The relationship between the mechanical strength and electrical conductivity of the hardened conductive CNT ink was studied, which helped determine the optimized concentration of CNT particles in the conductive CNT ink. Subsequently, a piezoresistive sensor was designed, fabricated, and evaluated. The conductive CNT ink-based piezoresistive sensor showed high sensitivity and good repeatability with respect to a wide range of external forces. The effect of the concentration of CNT particles on the viscosity of the conductive CNT ink was also investigated, providing a better understanding of the entanglement of CNT particles within the silicone elastomer. A coating test using the conductive CNT ink with a paper cutting machine demonstrated its potential for adaptation to various printing techniques, including screen printing. The proposed conductive CNT ink, characterized by a simple chemical composition, facile fabrication process, use of non-toxic elements, high electrical conductivity, and stretchability, combined with an extended duration, has the potential to be applied for multiple purposes, such as various types of flexible and wearable electronics. Full article
Show Figures

Figure 1

24 pages, 2330 KB  
Review
Analytical Determination of Heavy Metals in Water Using Carbon-Based Materials
by Zhazira Mukatayeva, Diana Konarbay, Yrysgul Bakytkarim, Nurgul Shadin and Yerbol Tileuberdi
Molecules 2026, 31(1), 5; https://doi.org/10.3390/molecules31010005 - 19 Dec 2025
Viewed by 781
Abstract
This review presents a critical and comparative analysis of carbon-based electrochemical sensing platforms for the determination of heavy metal ions in water, with emphasis on Pb2+, Cd2+, and Hg2+. The growing discharge of industrial and mining effluents [...] Read more.
This review presents a critical and comparative analysis of carbon-based electrochemical sensing platforms for the determination of heavy metal ions in water, with emphasis on Pb2+, Cd2+, and Hg2+. The growing discharge of industrial and mining effluents has led to persistent contamination of aquatic environments by toxic metals, creating an urgent need for sensitive, rapid, and field-deployable analytical technologies. Carbon-based nanomaterials, including graphene, carbon nanotubes (CNTs), and MXene, have emerged as key functional components in modern electrochemical sensors due to their high electrical conductivity, large surface area, and tunable surface chemistry. Based on reported studies, typical detection limits for Pb2+ and Cd2+ using differential pulse voltammetry (DPV) on glassy carbon and thin-film electrodes are in the range of 0.4–1.2 µg/L. For integrated thin-film sensing systems, limits of detection of 0.8–1.2 µg/L are commonly achieved. MXene-based platforms further enhance sensitivity and enable Hg2+ detection with linear response ranges typically between 1 and 5 µg/L, accompanied by clear electrochemical or optical signals. Beyond conventional electrochemical detection, this review specifically highlights self-sustaining visual sensors based on MXene integrated with enzyme-driven bioelectrochemical systems, such as glucose oxidase (GOD) and Prussian blue (PB) assembled on ITO substrates. These systems convert chemical energy into measurable colorimetric signals without external power sources, enabling direct visual identification of Hg2+ ions. Under optimized conditions (e.g., 5 mg/mL GOD and 5 mM glucose), stable and distinguishable color responses are achieved for rapid on-site monitoring. Overall, this review not only summarizes current performance benchmarks of carbon-based sensors but also identifies key challenges, including long-term stability, selectivity under multi-ion interference, and large-scale device integration, while outlining future directions toward portable multisensor water-quality monitoring systems. Full article
Show Figures

Graphical abstract

16 pages, 3254 KB  
Article
Ultra-Long Carbon Nanotubes-Based Flexible Transparent Heaters
by Nov Dubnov, Shahar Artzi, Yousef Farraj, Ronen Gottesman, Shuki Yeshurun and Shlomo Magdassi
Coatings 2025, 15(12), 1487; https://doi.org/10.3390/coatings15121487 - 16 Dec 2025
Viewed by 681
Abstract
Transparent conductive materials (TCMs) are essential for optoelectrical devices ranging from smart windows and defogging films to soft sensors, display technologies, and flexible electronics. Materials, such as indium tin oxide (ITO) and silver nanowires (AgNWs), are commonly used and offer high optical transmittance [...] Read more.
Transparent conductive materials (TCMs) are essential for optoelectrical devices ranging from smart windows and defogging films to soft sensors, display technologies, and flexible electronics. Materials, such as indium tin oxide (ITO) and silver nanowires (AgNWs), are commonly used and offer high optical transmittance and electrical conductivity, but suffer from brittleness, oxidation susceptibility, and require high-cost materials, greatly limiting their use. Carbon nanotube (CNT) networks provide a promising alternative, featuring mechanical compliance, chemical robustness, and scalable processing. This study reports an aqueous ink formulation composed of ultra-long mix-walled carbon nanotubes (UL-CNTs), compatible with the flow coating process, yielding uniform transparent conductive films (TCFs) on polyethylene terephthalate (PET), glass, and polycarbonate (PC). The resulting films exhibit tunable transmittance (85%–88% for single layers; ~57% for three layers at 550 nm) and sheet resistance of 7.5 kΩ/□ to 1.5 kΩ/□ accordingly. These TCFs maintain stable sheet resistance for over 5000 bending cycles and show excellent mechanical durability with negligible effects on heating performance. Post-deposition treatments, including nitric acid vapor doping or flash photonic heating (FPH), further reduce sheet resistance by up to 80% (7.5 kΩ/□ to 1.2 kΩ/□). X-ray photoelectron spectroscopy (XPS) results in reduced surface oxygen content after FPH. The photonic-treated heaters attain ~100 °C within 20 s at 100 V. This scalable, water-based process provides a pathway toward low-cost, flexible, and stretchable devices in a variety of fields, including printed electronics, optoelectronics, and thermal actuators. Full article
Show Figures

Figure 1

22 pages, 3823 KB  
Review
Carbon Nanotube-Based Self-Powered Sensors for Autonomous Environmental and Biomedical Monitoring
by Minwoo Kim, Younghun Noh, Hyunsoo Kim and Yongwoo Jang
Chemosensors 2025, 13(11), 388; https://doi.org/10.3390/chemosensors13110388 - 4 Nov 2025
Cited by 2 | Viewed by 1771
Abstract
Self-powered sensor technologies are receiving increasing attention owing to their ability to operate independently without the need for external batteries or power supplies. This autonomy enables continuous and real-time monitoring in various applications. Carbon nanotubes (CNTs) are particularly promising as electrode materials and [...] Read more.
Self-powered sensor technologies are receiving increasing attention owing to their ability to operate independently without the need for external batteries or power supplies. This autonomy enables continuous and real-time monitoring in various applications. Carbon nanotubes (CNTs) are particularly promising as electrode materials and energy-harvesting components, owing to their excellent electrical conductivity, mechanical robustness, and tunable surface properties. This review provides a concise overview and critical perspectives on recent progress in CNT-based self-powered sensors, focusing on their structural designs, operating mechanisms, and application areas. The sensors are classified according to their practical application environments, including environmental, wearable, and implantable applications, rather than by their energy-harvesting mechanisms or detection targets. Furthermore, current critical challenges, such as durability, scalable fabrication, and in vivo validation, which must be solved to achieve fully autonomous CNT-based sensors for healthcare and environmental monitoring, are discussed. This review underscores the pivotal role of CNT-based self-powered sensors in driving next-generation autonomous monitoring technologies and offers insights for the implementation of such sensors in practical biomedical and environmental applications. Full article
(This article belongs to the Special Issue Application of Carbon Nanotubes in Sensing)
Show Figures

Figure 1

18 pages, 3340 KB  
Article
Experimental Investigation of 3D-Printed TPU Triboelectric Composites for Biomechanical Energy Conversion in Knee Implants
by Osama Abdalla, Milad Azami, Amir Ameli, Emre Salman, Milutin Stanacevic, Ryan Willing and Shahrzad Towfighian
Sensors 2025, 25(20), 6454; https://doi.org/10.3390/s25206454 - 18 Oct 2025
Cited by 2 | Viewed by 1082
Abstract
Although total knee replacements have an insignificant impact on patients’ mobility and quality of life, real-time performance monitoring remains a challenge. Monitoring the load over time can improve surgery outcomes and early detection of mechanical imbalances. Triboelectric nanogenerators (TENGs) present a promising approach [...] Read more.
Although total knee replacements have an insignificant impact on patients’ mobility and quality of life, real-time performance monitoring remains a challenge. Monitoring the load over time can improve surgery outcomes and early detection of mechanical imbalances. Triboelectric nanogenerators (TENGs) present a promising approach as a self-powered sensor for load monitoring in TKR. A TENG was fabricated with dielectric layers consisting of Kapton tape and 3D-printed thermoplastic polyurethane (TPU) matrix incorporating CNT and BTO fillers, separated by an air gap and sandwiched between two copper electrodes. The sensor performance was optimized by varying the concentrations of BTO and CNT to study their effect on the energy-harvesting behavior. The test results demonstrate that the BTO/TPU composite that has 15% BTO achieved the maximum power output of 11.15 μW, corresponding to a power density of 7 mW/m2, under a cyclic compressive load of 2100 N at a load resistance of 1200 MΩ, which was the highest power output among all the tested samples. Under a gait load profile, the same TENG sensor generated a power density of 0.8 mW/m2 at 900 MΩ. By contrast, all tested CNT/TPU-based TENG produced lower output, where the maximum generated apparent power output was around 8 μW corresponding to a power density of 4.8 mW/m2, confirming that using BTO fillers had a more significant impact on TENG performance compared with CNT fillers. Based on our earlier work, this power is sufficient to operate the ADC circuit. Furthermore, we investigated the durability and sensitivity of the 15% BTO/TPU samples, where it was tested under a compressive force of 1000 N for 15,000 cycles, confirming the potential of long-term use inside the TKR. The sensitivity analysis showed values of 37.4 mV/N for axial forces below 800 N and 5.0 mV/N for forces above 800 N. Moreover, dielectric characterization revealed that increasing the BTO concentration improves the dielectric constant while at the same time reducing the dielectric loss, with an optimal 15% BTO concentration exhibiting the most favorable dielectric properties. SEM images for BTO/TPU showed that the 10% and 15% BTO/TPU composites showed better morphological characteristics with lower fabrication defects compared with higher filler concentrations. Our BTO/TPU-based TENG sensor showed robust performance, long-term durability, and efficient energy conversion, supporting its potential for next-generation smart total knee replacements. Full article
(This article belongs to the Special Issue Wireless Sensor Networks with Energy Harvesting)
Show Figures

Figure 1

16 pages, 2760 KB  
Article
Simple Moisture Sensing Element Using Carbon Nanotube Composite Paper
by Takahide Oya, Tadashi Saito, Yuma Morita and Koya Arai
Chemosensors 2025, 13(10), 373; https://doi.org/10.3390/chemosensors13100373 - 16 Oct 2025
Cited by 2 | Viewed by 980
Abstract
We propose a unique moisture sensing element (including humidity sensor) using carbon nanotube (CNT) composite paper. The CNT composite paper is a composite material consisting of CNTs and cellulose paper, which can be easily produced using a method based on the Japanese washi [...] Read more.
We propose a unique moisture sensing element (including humidity sensor) using carbon nanotube (CNT) composite paper. The CNT composite paper is a composite material consisting of CNTs and cellulose paper, which can be easily produced using a method based on the Japanese washi papermaking process. Since this composite paper contains CNTs, it is a conductive paper. In addition, the cellulose fibers that make up the paper are known to show a volume change of up to 35% with humidity. The proposed moisture sensing element uses this volume change and the electrical resistance derived from the CNT network contained in the composite paper. Through various experiments, it was confirmed that the electrical resistance of the CNT composite paper changes in response to moisture of various sizes, such as water droplets and vapors (humidity). It was concluded that these changes were the result of the volume change of paper fibers due to moisture, which greatly affected the structure of the CNT network contained within the composite paper. The results of this study will be useful for the practical application of simple and flexible paper-based moisture sensing elements in the near future. Full article
(This article belongs to the Special Issue Application of Carbon Nanotubes in Sensing)
Show Figures

Figure 1

36 pages, 3836 KB  
Review
Carbon Nanotube-Based Chemical Sensors: Sensing Mechanism, Functionalization and Applications
by Jie Tang, Ruirui Li, Subhan Mahmood, Jiying Li and Shun Yao
Chemosensors 2025, 13(10), 367; https://doi.org/10.3390/chemosensors13100367 - 10 Oct 2025
Cited by 6 | Viewed by 3840
Abstract
Carbon nanotubes (CNTs) have opened new routes in the field of chemical sensing due to their unparalleled electrical conductivity, high surface area, and versatile functionalization capabilities. This review systematically examined the latest advancements in CNT-based chemical sensors, with a focus on their sensing [...] Read more.
Carbon nanotubes (CNTs) have opened new routes in the field of chemical sensing due to their unparalleled electrical conductivity, high surface area, and versatile functionalization capabilities. This review systematically examined the latest advancements in CNT-based chemical sensors, with a focus on their sensing mechanism, functionalization strategies, and applications. A spotlight was cast on the wide-ranging applications of CNT-based chemical sensors, spanning environmental analysis, drug detection, healthcare, food quality control, gases detection, strain sensing, etc. Finally, through a comprehensive SWOT analysis, the strengths, weaknesses, opportunities, and existing threats, along with emerging trends of CNTs in the sensing field, were elucidated. This review systematically summarized the applications of CNTs across six major fields, highlighting more than 60 CNT-based sensing materials. We aim to provide a forward-looking perspective on how CNTs will continue to shape the future of chemical sensing. Full article
(This article belongs to the Special Issue Application of Carbon Nanotubes in Sensing)
Show Figures

Graphical abstract

36 pages, 2691 KB  
Review
Advanced Electrochemical Sensors for Rapid and Sensitive Monitoring of Tryptophan and Tryptamine in Clinical Diagnostics
by Janani Sridev, Arif R. Deen, Md Younus Ali, Wei-Ting Ting, M. Jamal Deen and Matiar M. R. Howlader
Biosensors 2025, 15(9), 626; https://doi.org/10.3390/bios15090626 - 19 Sep 2025
Viewed by 2229
Abstract
Tryptophan (Trp) and tryptamine (Tryp), critical biomarkers in mood regulation, immune function, and metabolic homeostasis, are increasingly recognized for their roles in both oral and systemic pathologies, including neurodegenerative disorders, cancers, and inflammatory conditions. Their rapid, sensitive detection in biofluids such as saliva—a [...] Read more.
Tryptophan (Trp) and tryptamine (Tryp), critical biomarkers in mood regulation, immune function, and metabolic homeostasis, are increasingly recognized for their roles in both oral and systemic pathologies, including neurodegenerative disorders, cancers, and inflammatory conditions. Their rapid, sensitive detection in biofluids such as saliva—a non-invasive, real-time diagnostic medium—offers transformative potential for early disease identification and personalized health monitoring. This review synthesizes advancements in electrochemical sensor technologies tailored for Trp and Tryp quantification, emphasizing their clinical relevance in diagnosing conditions like oral squamous cell carcinoma (OSCC), Alzheimer’s disease (AD), and breast cancer, where dysregulated Trp metabolism reflects immune dysfunction or tumor progression. Electrochemical platforms have overcome the limitations of conventional techniques (e.g., enzyme-linked immunosorbent assays (ELISA) and mass spectrometry) by integrating innovative nanomaterials and smart engineering strategies. Carbon-based architectures, such as graphene (Gr) and carbon nanotubes (CNTs) functionalized with metal nanoparticles (Ni and Co) or nitrogen dopants, amplify electron transfer kinetics and catalytic activity, achieving sub-nanomolar detection limits. Synergies between doping and advanced functionalization—via aptamers (Apt), molecularly imprinted polymers (MIPs), or metal-oxide hybrids—impart exceptional selectivity, enabling the precise discrimination of Trp and Tryp in complex matrices like saliva. Mechanistically, redox reactions at the indole ring are optimized through tailored electrode interfaces, which enhance reaction kinetics and stability over repeated cycles. Translational strides include 3D-printed microfluidics and wearable sensors for continuous intraoral health surveillance, demonstrating clinical utility in detecting elevated Trp levels in OSCC and breast cancer. These platforms align with point-of-care (POC) needs through rapid response times, minimal fouling, and compatibility with scalable fabrication. However, challenges persist in standardizing saliva collection, mitigating matrix interference, and validating biomarkers across diverse populations. Emerging solutions, such as AI-driven analytics and antifouling coatings, coupled with interdisciplinary efforts to refine device integration and manufacturing, are critical to bridging these gaps. By harmonizing material innovation with clinical insights, electrochemical sensors promise to revolutionize precision medicine, offering cost-effective, real-time diagnostics for both localized oral pathologies and systemic diseases. As the field advances, addressing stability and scalability barriers will unlock the full potential of these technologies, transforming them into indispensable tools for early intervention and tailored therapeutic monitoring in global healthcare. Full article
(This article belongs to the Special Issue Nanomaterial-Based Biosensors for Point-of-Care Testing)
Show Figures

Figure 1

25 pages, 1808 KB  
Review
Nanomaterial-Powered Biosensors: A Cutting-Edge Review of Their Versatile Applications
by Payal Patial, Manish Deshwal, Shonak Bansal, Anjana Sharma, Kamaldeep Kaur and Krishna Prakash
Micromachines 2025, 16(9), 1042; https://doi.org/10.3390/mi16091042 - 11 Sep 2025
Cited by 5 | Viewed by 4067
Abstract
Optimal sensing devices exhibit a combination of key performance attributes, including an extensive detection limit, exceptional selectivity, high sensitivity, consistent repeatability, precise measurement, and rapid response times with efficient analyte flow. In recent years, biosensing platforms incorporating nanoscale materials have garnered considerable attention [...] Read more.
Optimal sensing devices exhibit a combination of key performance attributes, including an extensive detection limit, exceptional selectivity, high sensitivity, consistent repeatability, precise measurement, and rapid response times with efficient analyte flow. In recent years, biosensing platforms incorporating nanoscale materials have garnered considerable attention due to their diverse applications across various scientific and technological domains. The integration of nanoparticles (NPs) in biosensor design primarily bridges the dimensional gap between the signal transduction element and the biological recognition component, both of which operate at nanometer scales. The synergistic combination of NPs with electrochemical techniques has facilitated the development of biosensors characterized by enhanced sensitivity and superior analyte discrimination capabilities. This comprehensive analysis examines the evolution and recent advancements in nanomaterial (NM)-based biosensors, encompassing an extensive array of nanostructures. These consists of one-dimensional nanostructures including carbon nanotubes (CNTs), nanowires (NWs), nanorods (NRs), and quantum dots (QDs), as well as noble metal and metal and metal oxide nanoparticles (NPs). The article examines how advancements in biosensing techniques across a range of applications have been fueled by the growth of nanotechnology. Researchers have significantly improved biosensor performance parameters by utilizing the distinct physiochemical properties of these NMs. The developments have increased the potential uses of nanobiosensors in a wide range of fields, from food safety and biodefense to medical diagnostics and environmental monitoring. The continuous developments in NM-based biosensors are the result of the integration of several scientific areas, such as analytical chemistry, materials science, and biotechnology. This interdisciplinary approach continues to drive innovations in sensor design, signal amplification strategies, and data analysis techniques, ultimately leading to more sophisticated and capable biosensing platforms. As the field progresses, challenges related to the scalability, reproducibility, and long-term stability of nanobiosensors are being addressed through innovative fabrication methods and surface modification techniques. These efforts aim to translate the promising results observed in laboratory settings into practical, commercially viable biosensing devices that can address real-world analytical challenges across various sectors. Full article
Show Figures

Figure 1

18 pages, 2872 KB  
Review
A Concise Review of State-of-the-Art Sensing Technologies for Bridge Structural Health Monitoring
by Xiushan Kang, Bing Zhu, Yougang Cai, Yufeng Xiao, Ningbo Liu, Zhongxu Guo, Qi-Ang Wang and Yang Luo
Sensors 2025, 25(17), 5460; https://doi.org/10.3390/s25175460 - 3 Sep 2025
Cited by 2 | Viewed by 3642
Abstract
Against the backdrop of increasing demands for the safety and longevity of the bridge infrastructure, this review synthesizes the recent advances in structural health monitoring (SHM) sensing systems. Carbon nanotube (CNT), piezoelectric, RFID, wireless, fiber optic, and computer-vision-based sensing are thoroughly explored and [...] Read more.
Against the backdrop of increasing demands for the safety and longevity of the bridge infrastructure, this review synthesizes the recent advances in structural health monitoring (SHM) sensing systems. Carbon nanotube (CNT), piezoelectric, RFID, wireless, fiber optic, and computer-vision-based sensing are thoroughly explored and elucidated in the existing literature survey that distills their working principles, documented deployments, and anticipated research directions. CNT sensors detect minute resistance variations for strain and crack surveillance; piezoelectric devices transduce mechanical stimuli into high-resolution electrical signals; RFID tags combine location tracking with modular sensing and wireless data relay; and wireless sensing technology integrates sensor nodes with microprocessors and communication modules, which can facilitate efficient data processing and autonomous management. Fiber optic sensing technology, known for precision and interference resistance, is ideal for high-precision monitoring under strong electromagnetic interference conditions, and vision-based systems emulate human perception to extract geometric descriptors via image analytics. The comparative analysis reveals complementary strengths that guide practitioners in selecting optimal sensor suites for specific bridge conditions. The findings underscore the transformative role of these technologies in enhancing SHM reliability and suggest that synergistic integration with robotics and emerging materials will further advance future resilient monitoring frameworks. Full article
(This article belongs to the Section Physical Sensors)
Show Figures

Figure 1

Back to TopTop