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6 Results Found

  • Article
  • Open Access
1 Citations
2,046 Views
11 Pages

Evaluation of Bortezomib-BeEAM (2BeEAM) as Chemotherapy Regimen Prior to ASCT in Patients with Mantle Cell Lymphoma

  • Fabrizio Huwyler,
  • Rebekka Kunz,
  • Ulrike Bacher,
  • Michèle Hoffmann,
  • Urban Novak,
  • Michael Daskalakis,
  • Yara Banz and
  • Thomas Pabst

31 March 2023

(1) Background: First-line therapy in fit MCL patients may comprise high-dose chemotherapy (HDCT) with autologous transplantation to consolidate remission before maintenance treatment. However, optimization of HDCT is an unmet clinical need given the...

  • Article
  • Open Access
1 Citations
2,154 Views
12 Pages

BeEAM Conditioning including High-Dose Bendamustine before Autologous Stem Cell Transplantation Is Safe and Effective in Patients with Waldenstrom’s Macroglobulinemia

  • Alexander D. Heini,
  • Philipp Beck,
  • Ulrike Bacher,
  • Katja Seipel,
  • Thilo Zander,
  • Michael Daskalakis and
  • Thomas Pabst

19 March 2023

High-dose chemotherapy (HDCT) with autologous stem cell transplantation (ASCT) is an option to consolidate remission in Waldenstrom’s macroglobulinemia (WM), particularly in selected younger patients with chemosensitive disease. BEAM, consistin...

  • Article
  • Open Access
5 Citations
2,877 Views
10 Pages

BeEAM High-Dose Chemotherapy with Polatuzumab (Pola-BeEAM) before ASCT in Patients with DLBCL—A Pilot Study

  • Tanja Stoffel,
  • Ulrike Bacher,
  • Yara Banz,
  • Michael Daskalakis,
  • Urban Novak and
  • Thomas Pabst

28 June 2022

(1) Introduction: BEAM is a high-dose chemotherapy (HDCT) frequently administered before autologous stem cell transplantation (ASCT) in diffuse large B-cell lymphoma (DLBCL). Bendamustine replacing BCNU (BeEAM) is similarly effective at lower toxicit...

  • Article
  • Open Access
3 Citations
2,247 Views
12 Pages

Combining BeEAM with Brentuximab Vedotin for High-Dose Therapy in CD30 Positive Lymphomas before Autologous Transplantation—A Phase I Study

  • Christian Rausch,
  • Ulrike Bacher,
  • Manuela Rabaglio,
  • Corinne Vorburger,
  • Anke Klingenberg,
  • Yara Banz,
  • Michael Daskalakis and
  • Thomas Pabst

13 September 2022

The prognosis for patients with CD30+ lymphomas (Hodgkin lymphoma and various T-cell lymphomas) relapsing after autologous stem cell transplantation (ASCT) is critical. Brentuximab vedotin (BV), an ADC targeting CD30, is an obvious candidate for incl...

  • Article
  • Open Access
1 Citations
2,241 Views
18 Pages

Verification of a Modeling Toolkit for the Design of Building Electrical Distribution Systems

  • Anay Waghale,
  • Shat Pratoomratana,
  • Tianna-Kaye Woodstock,
  • Karthikeya Devaprasad and
  • Michael Poplawski

5 October 2023

DC electrical distribution systems offer many potential advantages over their AC counterparts. They can facilitate easier integration with distributed energy resources, improve system energy efficiency by eliminating AC/DC converters at end-use devic...

  • Article
  • Open Access
5 Citations
2,271 Views
46 Pages

A Modeling Toolkit for Comparing AC and DC Electrical Distribution Efficiency in Buildings

  • Avpreet Othee,
  • James Cale,
  • Arthur Santos,
  • Stephen Frank,
  • Daniel Zimmerle,
  • Omkar Ghatpande,
  • Gerald Duggan and
  • Daniel Gerber

25 March 2023

Recently, there has been considerable research interest in the potential for DC distribution systems in buildings instead of the traditional AC distribution systems. Due to the need for performing power conversions between DC and AC electricity, DC d...