- Article
Stereospecificity of Ginsenoside AD-1 and AD-2 Showed Anticancer Activity via Inducing Mitochondrial Dysfunction and Reactive Oxygen Species Mediate Cell Apoptosis
- Xude Wang,
- Meng Ding,
- Hong Zhao,
- Mengru Zhou,
- Xuan Lu,
- Yuanyuan Sun,
- Qinggao Zhang,
- Yuqing Zhao and
- Ruoyu Wang
In this paper, the anti-cancer activity and molecular mechanisms of the isomers of AD-1 and AD-2 (20(R)-AD-1, 20(R)-AD-2, 20(S)-AD-1 and 20(S)-AD-2) were investigated. The results indicated that all of the four compounds obviously suppressed the viab...