Special Issue "Gene Therapy with Emphasis on RNA Interference"
A special issue of Viruses (ISSN 1999-4915).
Deadline for manuscript submissions: closed (28 February 2015) | Viewed by 31133
Interests: viral gene therapy; viral vaccines; gene expression using viral vectors; structural biology
Special Issues, Collections and Topics in MDPI journals
Special Issue in Biomedicines: Gene Therapy Coming of Age
Special Issue in Viruses: RNA Interference (RNAi) for Antiviral Therapy
Special Issue in Viruses: Vaccines and Therapeutics against Coronaviruses
Special Issue in Biomedicines: Viral Vectors for Immunotherapy: Vaccines and Cancer Immunotherapy
Special Issue in Viruses: Self-Replicating RNA Viruses
The progress in gene therapy has been hampered by delivery inefficacy and safety concerns. Recent progress has casted some promising light on future development. A number of viral vectors have been re-engineered for improved delivery and enhanced safety. In this context, adenovirus, adeno-associated virus, lentivirus, retroviruses and other virus vectors have provided therapeutic efficacy for various diseases such as severe combined immunodeficiency, hemophilia, cancer and infectious diseases. The discovery of RNA interference, particularly the use of short interfering RNA and micro-RNA for reversible gene silencing, has substantially widened the application range of gene therapy. In this Special Issue, applications of various viral vectors and their use in gene therapy are reviewed with a special emphasis on RNA interference.
Dr. Kenneth Lundstrom
Manuscript Submission Information
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- viral vectors
- severe combined immunodeficiency
- infectious diseases
- RNA interference
- gene silencing