Special Issue "Gene Therapy Coming of Age"
Deadline for manuscript submissions: closed (31 March 2021).
Interests: viral gene therapy; viral vaccines; gene expression using viral vectors; structural biology; epigenetics; nutrigenomics
Special Issues and Collections in MDPI journals
Special Issue in Diseases: Gene Therapy
Special Issue in Viruses: RNA Interference (RNAi) for Antiviral Therapy
Special Issue in Viruses: Vaccines and Therapeutics against Coronaviruses
Special Issue in Biomedicines: Viral Vectors for Immunotherapy: Vaccines and Cancer Immunotherapy
Gene therapy was once considered as the medicine of the future, back in the late 1990s, but it then suffered some unexpected setbacks in terms of virus-based delivery approaches. Nevertheless, gene therapy is now experiencing a second coming due to its improved efficacy and safety of vector delivery. This has led to the initiation of a large number of clinical trials and even approval of the first gene therapy drugs. Furthermore, recent progress in RNA interference, RNA delivery, and gene-editing technologies has broadened the application range of gene therapy. Today, both viral and nonviral vectors have found various applications for treatment of several diseases, such as cancer, metabolic, neurodegenerative, cardiovascular, and muscular diseases. The Special Issue on Gene Therapy in Biomedicines is therefore a particularly topical addition to the field, providing up-to-date insight into delivery vector types, safety-related issues, proof-of-principle in preclinical disease models, clinical trials in healthy volunteers and patients, and approval of gene therapy-based drugs.
Dr. Kenneth Lundstrom
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- viral vectors
- nonviral vectors
- RNA interference
- gene editing
- clinical trials